Results 141 to 150 of about 29,745,998 (266)
The role of the VEGF-C/VEGFR-3 axis in cancer progression [PDF]
, 2009 [[abstract]]Vascular endothelial growth factor (VEGF) receptor 3 (VEGFR-3) (also called VEGFR-3) is activated by its specific ligand, VEGF-C, which promotes cancer progression.
Jen-Liang Su;C-J Yen;P-S Chen;S-E Chung;C-C Hong;I-H Kuo;H-Y Chen;Mien-Chie Hung;M-L Kuo +1 more
core
, 2011 Supplementary Figure 1 from Assessing the Activity of Cediranib, a VEGFR-2/3 Tyrosine Kinase Inhibitor, against VEGFR-1 and Members of the Structurally Related PDGFR ...
Kirsty Ratcliffe (14981885) +19 more
core +1 more source
Cytoskeletal Dynamics in Cancer: From Pathogenesis to Treatment
MedComm, Volume 7, Issue 10, October 2026.This review systematically addresses the fundamental roles of the cytoskeleton (actin filaments, microtubules, and intermediate filaments) in cancer progression. We focus on how cytoskeletal dynamics regulate tumor proliferation, metastasis, and programmed cell death, while also modulating the immune microenvironment. Understanding these mechanisms may
Jie Chen +9 more
wiley +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban, 2015 摘 要： 【目的】 为了分析Ｄｌｌ４、 ＶＥＧＦＲ－１、 ＶＥＧＦＲ－２在视网膜新生血管中的表达，探讨Ｎｏｔｃｈ１－Ｄｌｌ４信号通路在氧诱导视网膜病小鼠新生血管形成中的作用。【方法】 选用鼠龄７ ｄ的 Ｃ５７ＢＬ／６Ｊ 新生鼠３０只，分成实验组和对照组。实验组１５只，在氧浓度为（７５±２）％的密闭容器中生长５ ｄ，回到室内正常空气中；对照组１５只，在室内正常空气中生长。两组各取产后７ ｄ（７ ｄ ｐｏｓｔ－ｐａｒｔｕｍ，ｐ７）、ｐ１２、ｐ１７新生鼠 ５只，摘除眼球，取视网膜提取ＲＮＡ，以ＲＴ－ＰＣＲ ...
doaj
Coordinated activation of VEGFR-1 and VEGFR-2 is a potent arteriogenic stimulus leading to enhancement of regional perfusion [PDF]
, 2017 Objective: The process of arteriogenesis is driven by various growth factors including vascular endothelial growth factor (VEGF)-A, which mediates its activity through VEGFR-2 (Flk-1/KDR) on endothelial cells and through VEGFR-1 (Flt-1) on endothelial ...
Wangler, Christoph +9 more
core
Machine Learning‐Based Development of Gadolinium Binding Peptides
NMR in Biomedicine, Volume 39, Issue 10, October 2026.In this study, Dayan et al. employed a machine‐learning‐driven peptide‐evolution platform, the Protein Optimization Engineering Tool (POET), to design and optimize short Gd‐binding motifs to enhance longitudinal relaxivity (r1). ABSTRACT Gadolinium‐based contrast agents (GBCAs) are indispensable tools in magnetic resonance imaging (MRI), yet their ...
Nir A. Dayan +7 more
wiley +1 more source
VEGFR-1/Flt-1 inhibition increases angiogenesis and improves muscle function in a mouse model of Duchenne muscular dystrophy. [PDF]
Mol Ther Methods Clin Dev, 2021 Bosco J +19 more
europepmc +1 more source
VEGFR-2 and VEGFR-3 Expression as a Function of Jagged-1 Over-Expression in HUVEC Cells [PDF]
, 2014 Angiogenesis is the sprouting of new blood vessels from pre-existing vessels initiated from vascular endothelial cells in response to exogenous chemical signals.
Stubbs, Caleb
core
, 2011 Supplementary Tables 1-3 from Assessing the Activity of Cediranib, a VEGFR-2/3 Tyrosine Kinase Inhibitor, against VEGFR-1 and Members of the Structurally Related PDGFR ...
Kirsty Ratcliffe (14981885) +19 more
core +1 more source
International Endodontic Journal, Volume 59, Issue 10, Page 2143-2163, October 2026.ABSTRACT Background Dental pulp inflammation triggers immune responses involving macrophages and dental pulp stem cells (DPSCs), which interact to regulate angiogenesis essential for tissue repair. M1 pro‐inflammatory macrophages predominate early in pulpitis, and clarifying their angiogenic role is vital in identifying inflammatory regenerative ...
Dineshi Sewvandi Thalakiriyawa +5 more
wiley +1 more source