Results 101 to 110 of about 29,745,998 (266)

VEGFR-3 directly interacts with PI3K to regulate lymphangiogenesis

open access: yes, 2012
VEGFR-3 directly interacts with PI3K to regulate ...
Elizabeth D Williams (19147639)   +3 more
core  

The FGF/FGFR System in the Biology and Therapeutic Landscape of Pediatric CNS Tumors

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Central nervous system (CNS) tumors are the most common solid malignancies in children, comprising a highly heterogeneous group of neoplasms defined by distinct molecular alterations and clinical behaviors. Advances in molecular genetics have underscored the relevance of specific signaling pathways in driving pediatric tumorigenesis, among ...
Serena Filiberti   +6 more
wiley   +1 more source

Notch, IL-1 and leptin crosstalk outcome (NILCO) is critical for leptin-induced proliferation, migration and VEGF/VEGFR-2 expression in breast cancer.

open access: yesPLoS ONE, 2011
High levels of pro-angiogenic factors, leptin, IL-1, Notch and VEGF (ligands and receptors), are found in breast cancer, which is commonly correlated with metastasis and lower survival of patients.
Shanchun Guo, Ruben R Gonzalez-Perez
doaj   +1 more source

VEGFR-1, Bcl-2, and HO-1 Ratios in Pregnant Women With Hypertension

open access: yesClinical and Applied Thrombosis/Hemostasis, 2013
Backgound/Aim: Preeclampsia (PE) is a multisystem disease resulting in high maternal–fetal morbidity and mortality. The aim of the study was to investigate antiangiogenesis-associated alterations in antiapoptotic and antioxidative proteins in PE. Method:
Varol, Fusun   +4 more
openaire   +2 more sources

Precisely Engineering Biomimetic Nanoparticles via Controlled Cell Membrane Coating

open access: yesSmall, EarlyView.
Precise engineering of cell membrane‐coated nanoparticles (CMNPs) requires coordinated control over particle size, coating integrity, and membrane leaflet orientation. This review integrates key synthesis parameters, assembly strategies, and analytical methods that govern these features, revealing how structural control underpins biomimetic function ...
Jie Lay Lim   +4 more
wiley   +1 more source

Analysis of results determination of level of vascular endothelial growth factor, receptor for vascular endothelial growth factor and big endotelin-1 in structure of arteriovenous malformations

open access: yesУкраїнська Інтервенційна Нейрорадіологія та Хірургія, 2022
Objective ‒ to assess the diagnostic significance of angiogenesis factors based on the study of the level of angiogenesis factors (vascular endothelial growth factor (VEGF-A), specific receptor for vascular endothelial growth factor (VEGFR-1 ...
I.V. Altman
doaj  

Rapamycin Inhibits Lymphatic Endothelial Cell Tube Formation by Downregulating Vascular Endothelial Growth Factor Receptor 3 Protein Expression

open access: yesNeoplasia: An International Journal for Oncology Research, 2012
Mammalian target of rapamycin (mTOR) controls lymphangiogenesis. However, the underlying mechanism is not clear. Here we show that rapamycin suppressed insulin-like growth factor 1 (IGF-1)- or fetal bovine serum (FBS)-stimulated lymphatic endothelial ...
Yan Luo   +9 more
doaj   +1 more source

Biomarkers to predict outcomes in diabetic foot ulcers

open access: yesVIEW, EarlyView.
Studies attempting to predict the healing outcome of diabetic foot ulcers (DFUs) have investigated various biological materials and recovered molecules that may aid in discriminating wounds that will heal and those that will not heal. This graphical abstract captures the commonly studied classes of biomarkers in the context of DFUs.
Julie Okiro   +6 more
wiley   +1 more source

Investigation of Site-Specific Differences in Glycan Microheterogeneity by N-Glycopeptide Mapping of VEGFR-IgG Fusion Protein

open access: yesMolecules, 2019
A biosimilar fusion protein VEGFR-IgG consisting of vascular endothelial growth factor receptors 1 and 2 (VEGFR-1, VEGFR-2) and the Fc portion of human IgG1 was prepared for this study.
Young Hye Hahm   +2 more
doaj   +1 more source

Mesenchymal Stem Cells From a Klinefelter Syndrome Patient: Functional Characterization and Therapeutic Implications

open access: yesAndrology, EarlyView.
ABSTRACT Background Cell therapy, particularly those utilizing mesenchymal stem/stromal cells (MSCs), is gaining traction as a therapeutic option for regenerative treatment in patients with limited therapeutic options. Although the safety of MSC‐based interventions is well established, uncertainties remain regarding how genetic abnormalities and ...
Marzena Zychowicz   +12 more
wiley   +1 more source

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