Lv-vegfr-10-Ig expression during BC transfating.
, 2019 (A) Control gastrula. Lv-vegfr-10-Ig is expressed at high levels by PMCs (arrow), as previously reported [9]. (B) PMC(−) embryo, 2 hpd. Expression of Lv-vegfr-10-Ig is evident in the invaginating vegetal plate (arrow), a region that includes presumptive ...
Ashrifia Adomako-Ankomah (7401002) +1 more
core +1 more source
Gene expression of VEGFR–1 and VEGFR–2 in HD1 and HD2.
, 2022 Median and standard error of gene expression of VEGFR–1 and VEGFR–2 at all points of investigation in native ECs of HD1 and HD2 are shown.
Christina Herre (12475755) +4 more
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Direct sensing of endothelial oxidants by vascular endothelial growth factor receptor-2 and c-Src. [PDF]
PLoS ONE, 2011 BACKGROUND: ADPH oxidase-derived reactive oxygen species (ROS) play important roles in redox homeostasis and signal transduction in endothelial cells (ECs).
Monica Lee, Wing C Choy, Md Ruhul Abid
doaj +1 more source
Lv-VEGFR-10-Ig is required for BC transfating.
, 2019 (A) MO knockdown strategy. Following the approach of Duloquin and coworkers [9], an MO was directed at the exon 2/intron 2 splice junction of the Lv-vegfr-10-Ig primary transcript. (B) RT-PCR analysis of morphant embryos. The Lv-vegfr-10-Ig MO produced a
Ashrifia Adomako-Ankomah (7401002) +1 more
core +1 more source
The structural and functional characterization of the extracellular domain of vascular endothelial growth factor receptors : their role in receptor activation and use as therapeutic targets [PDF]
, 2012 : The vascular endothelial growth factor (VEGF) family plays key roles in the development of the blood and lymphatic vasculature. Five members, VEGF A, B, -C, -D, and PlGF can be found in the human body.
Stuttfeld, Edward
core +1 more source
AI–Guided 4D Printing of Carnivorous Plants–Inspired Microneedles for Accelerated Wound Healing
Advanced Materials, EarlyView.This work presents an artificial intelligence (AI)‐guided 4D‐printed microneedle platform inspired by carnivorous plants for wound healing. A thermo‐responsive shape memory polymer enables body temperature–triggered self‐coiling for autonomous wound closure.
Hyun Lee +21 more
wiley +1 more source
Combating VEGFA‐siRNA‐Induced Metabolic Reprogramming via Glucose Utilization Deprivation
Advanced Science, EarlyView.An ionizable lipid nanoparticle co‐delivers VEGFA siRNA and glucose oxidase to tumors to counteract VEGFA knockdown‐induced, glutamine‐driven metabolic compensation. Enzymatic glucose consumption reverses the adaptive pathways and restores metabolism toward baseline, thereby sensitizing tumors to therapy.
Lulu Zheng +10 more
wiley +1 more source
Maternal Circulating CD34+VEGFR-2+ and CD133+VEGFR-2+ Progenitor Cells Increase During Normal Pregnancy but Are Reduced in Women With Preeclampsia [PDF]
Reproductive Sciences, 2010 Circulating endothelial progenitor cells (EPCs) may contribute to vascular endothelial cell homeostasis, and low levels of these cells are predictive of cardiovascular disease. We hypothesized that circulating EPCs increase in number during uncomplicated pregnancy but are reduced in women with preeclampsia.
Patrizia, Luppi +5 more
openaire +2 more sources
Advanced Science, EarlyView.This study reported renal‐clearable bio‐orthogonal near‐infrared fluorogenic probes (BGRs) that specifically imaging and urinalysis of granzyme B for dynamic evaluation of RCC immunotherapy. BGRs not only differentiate immunotherapeutic responses in orthotopic RCC mice, but also enable sensitive optical urinalysis of granzyme B in clinical specimens ...
Xingyue Yang +9 more
wiley +1 more source
Discovery of Dual VEGFR-2 and Tubulin Inhibitors with in Vivo Efficacy [PDF]
ACS Medicinal Chemistry Letters, 2010 In an effort to develop potent, orally bioavailable compounds for the treatment of neoplastic diseases, we developed a class of dual VEGFR-2 kinase and tubulin inhibitors. Targeting the VEGFR receptor kinase and tubulin structure allows for inhibition of both tumor cells and tumor vasculature. Previously, a combination of two compounds, a VEGF receptor
Eugene L Piatnitski, Chekler +7 more
openaire +2 more sources