Results 31 to 40 of about 94,145 (264)

Robust Adaptive Heterogeneous Vehicle Platoon Control Based on Disturbances Estimation and Compensation

IEEE Access
This paper presents an investigation into the problem of controlling a heterogeneous vehicle platoon, focusing on two aspects: the impact of noise in sensor measurements and the effect of road slope, wind, and rolling resistance on the longitudinal ...
Fernando Viadero-Monasterio, Miguel Melendez-Useros, Manuel Jimenez-Salas, Beatriz L. Boada   +3 more
doaj   +1 more source

Tires and Vehicle Lateral Dynamic Performance: A Corrective Algorithm for the Influence of Temperature

Machines, 2023
The automotive industry is experiencing increasing competition, and vehicle development is becoming increasingly complex. Manufacturers must therefore be able to rapidly compare the outcomes of experimental tests carried out under different conditions ...
Simone Savant, Henrique De Carvalho Pinheiro, Matteo Eugenio Sacchi, Cinzia Conti, Massimiliana Carello   +4 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Computationally Efficient Observer-Based Robust MPC for High-Speed Vehicle Centralized Trajectory Tracking With H_∞ Disturbance Attenuation

IEEE Open Journal of Intelligent Transportation Systems
This paper proposes a novel centralized trajectory tracking LPV controller for automated vehicles based on Observer-Based Robust Model Predictive Control (OB-RMPC), combining longitudinal and lateral control of the vehicle through a coupled dynamics ...
Manuel Jimenez-Salas, Fernando Viadero-Monasterio, Miguel Melendez-Useros, Beatriz L. Boada   +3 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Research on Reliability Evaluation Method of Aerospace Pyrotechnic Devices Based on Energy Measurement

Applied Sciences, 2020
High reliability is the basic requirement of aerospace pyrotechnic devices. Traditional reliability evaluation methods require a lot of tests, which become too expensive; therefore, the small-sample evaluation method is needed to reduce the cost.
Yubo Zhu, Jili Rong, Qianqiang Song, Zhipei Wu   +3 more
doaj   +1 more source

Drive: Dynamic Routing of Independent Vehicles [PDF]

Operations Research, 1998
We present DRIVE (Dynamic Routing of Independent VEhicles), a planning module to be incorporated in a decision support system for the direct transportation at Van Gend and Loos BV. Van Gend and Loos BV is the largest company providing road transportation in the Benelux, with about 1400 vehicles transporting 160,000 packages from thousands of senders ...
Martin W. P. Savelsbergh, Marc Sol
openaire   +2 more sources

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Fault‐Tolerant Robust Output‐Feedback Control of a Vehicle Platoon Considering Measurement Noise and Road Disturbances

IET Intelligent Transport Systems
As electric vehicle (EV) technology advances, platooning has emerged as a promising strategy to enhance energy efficiency and traffic flow. However, the effective deployment of EV platoons is challenged by the heterogeneous nature of vehicles ...
Fernando Viadero‐Monasterio, Miguel Meléndez‐Useros, Manuel Jiménez‐Salas, María Jesús López Boada   +3 more
doaj   +1 more source