Results 41 to 50 of about 127,844 (312)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

2022 Vehicle Dynamics seminar [Elektronisk resurs]

open access: yes, 2022
The seminar is held annually. The full title of this year's seminar was "2021 Vehicle Dynamics seminar -- Connected and Electric"
Drugge, Lars,   +2 more
core  

Broadband dual-anisotropic solid metamaterials

open access: yesScientific Reports, 2017
We have proposed solid elastic metamaterials with anisotropic stiffness and inertial mass simultaneously, denoted as the dual anisotropy, for the potential use of elastic wave controlling.
Yong Cheng, Xiaoming Zhou, Gengkai Hu
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Modern techniques for condition monitoring of railway vehicle dynamics

open access: yes, 2012
A modern railway system relies on sophisticated monitoring systems for maintenance and renewal activities. Some of the existing conditions monitoring techniques perform fault detection using advanced filtering, system identification and signal analysis ...
Gu, Fengshou   +6 more
core   +1 more source

Eigenvalue sensitivity analysis based on the transfer matrix method

open access: yesInternational Journal of Mechanical System Dynamics, 2021
For linear mechanical systems, the transfer matrix method is one of the most efficient modeling and analysis methods. However, in contrast to classical modeling strategies, the final eigenvalue problem is based on a matrix which is a highly nonlinear ...
Dieter Bestle
doaj   +1 more source

Tires and Vehicle Lateral Dynamic Performance: A Corrective Algorithm for the Influence of Temperature

open access: yesMachines, 2023
The automotive industry is experiencing increasing competition, and vehicle development is becoming increasingly complex. Manufacturers must therefore be able to rapidly compare the outcomes of experimental tests carried out under different conditions ...
Simone Savant   +4 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Heavy vehicle pitch dynamics and suspension tuning [PDF]

open access: yes, 2008
The influence of suspension tuning of passenger cars on bounce and pitch ride performance has been explored in a number of studies, while only minimal efforts have been made for establishing similar rules for heavy vehicles.
Cao, Dongpu   +2 more
core  

2021 Vehicle Dynamics seminar [Elektronisk resurs]

open access: yes, 2021
The seminar is held annually. The full title of this year's seminar was "2021 Vehicle Dynamics seminar -- for Future Mobility ...and not only Lateral"
Drugge, Lars,   +2 more
core  

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