Results 41 to 50 of about 88,031 (261)

Intrinsic Optimal Control for Mechanical Systems on Lie Group

Advances in Mathematical Physics, 2017
The intrinsic infinite horizon optimal control problem of mechanical systems on Lie group is investigated. The geometric optimal control problem is built on the intrinsic coordinate-free model, which is provided with Levi-Civita connection.
Chao Liu, Shengjing Tang, Jie Guo
doaj   +1 more source

Analysis for vehicle dynamics and steering system parameters effect on steering characteristics of steering feel (Fundamental study for performance design of objective target on steering feel)

Nihon Kikai Gakkai ronbunshu, 2017
The purpose of this paper is to clarify the effect of vehicle dynamics and steering system parameter on steering feel. The objective evaluation method for on-center and off-center evaluates steering effort, steering torque gradient, torque hysteresis and
Ikuo KUSHIRO, Keisuke SUZUKI
doaj   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Parametrisation of a Maxwell model for transient tyre forces by means of an extended firefly algorithm

Advances in Mechanical Engineering, 2016
Developing functions for advanced driver assistance systems requires very accurate tyre models, especially for the simulation of transient conditions. In the past, parametrisation of a given tyre model based on measurement data showed shortcomings, and ...
Andreas Hackl, Wolfgang Hirschberg, Cornelia Lex, Christian Magele   +3 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Experimental study on interaction between a positive mass and a negative effective mass through a mass–spring system

Theoretical and Applied Mechanics Letters, 2015
We investigate the interaction between a positive mass and a negative effective mass through a three-mass chain connected with elastic springs, a pair of masses is designed to have an effective negative mass, and it interacts with the third positive one ...
Jiao Zhou, Yong Cheng, Hongkuan Zhang, Guoliang Huang, Gengkai Hu   +4 more
doaj   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Robust Static Output Feedback Control of a Semi-Active Vehicle Suspension Based on Magnetorheological Dampers

Applied Sciences
This paper proposes a novel design method for a magnetorheological (MR) damper-based semi-active suspension system. An improved MR damper model that accurately describes the hysteretic nature and effect of the applied current is presented.
Fernando Viadero-Monasterio, Miguel Meléndez-Useros, Manuel Jiménez-Salas, Beatriz López Boada   +3 more
doaj   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Avoiding Lyapunov-Krasovskii Functionals: Simple Nonlinear Sampled–Data Control of a Semi-Active Suspension with Magnetorheological Dampers

Machines
This paper presents a novel control design methodology for a magnetorheological (MR) damper-based semi-active suspension system operating under communication-induced time delays, which introduce nonlinear sampled-data dynamics.
Fernando Viadero-Monasterio, Miguel Meléndez-Useros, Manuel Jiménez-Salas, María Jesús López Boada   +3 more
doaj   +1 more source