Results 81 to 90 of about 159,674 (308)

Introducing Borsantrazole: A Trifunctional Boron‐Based Pyrazole That Extends the Lifespan of Amyotrophic Lateral Sclerosis Mice

Advanced Science, EarlyView.
Herein we report a boron‐based pyrazole, (Borsantrazole ‐ a small molecule that selectively targets oxidative stress) that significantly increases survival, reduces weight loss, delays disease onset, and affects global protein changes in the SOD1‐G37R mouse model of ALS.
Nitesh Sanghai, Rhonda Kelley, Ying Lao, M. Immanuel Reyes Madlangsakay, Prasanta Paul, M. Alejandra Llanes‐Cuesta, Jun‐Feng Wang, René P. Zahedi, Jiming Kong, Geoffrey K. Tranmer   +9 more
wiley   +1 more source

Survey of Synanthropic Spiders in Ireland Reveals Expansion and Dominance of the Invasive Noble False Widow Steatoda nobilis in Urban Habitats (Araneae: Theridiidae)

Ecology and Evolution
Rapid urbanisation has led several spider species to adapt to synanthropic microhabitats and establish large populations outside of their native ranges.
Brandon L. Collier, Dayle Leonard, Keith Lyons, John P. Dunbar, Colin Lawton, Michel M. Dugon   +5 more
doaj   +1 more source

Varanid Lizard Venoms Disrupt the Clotting Ability of Human Fibrinogen through Destructive Cleavage

Toxins, 2019
The functional activities of Anguimorpha lizard venoms have received less attention compared to serpent lineages. Bite victims of varanid lizards often report persistent bleeding exceeding that expected for the mechanical damage of the bite.
James S. Dobson, Christina N. Zdenek, Chris Hay, Aude Violette, Rudy Fourmy, Chip Cochran, Bryan G. Fry   +6 more
doaj   +1 more source

Immune and clinical response to honeybee venom in beekeepers [PDF]

, 2016
OBJECTIVE The aim of the study was to assess immune response to honeybee venom in relation to the degree of exposure, time after a sting and clinical symptoms.
Kokot, Z.J., Zdzisława Kycler, Jan Matysiak, Joanna Matysiak, Zenon J Kokot, Paweł Dereziński, Kycler, Z., Matysiak, J., Derezinski, P., Breborowicz, A., Anna Bręborowicz   +10 more
core   +1 more source

B Cells are Activated via a Nanoporous Interface that Stabilizes Microvilli and Engages Mechanosensitive Ion Channels

Advanced Science, EarlyView.
B cells can be activated independently of antigen recognition via mechanical stimulation through nanoporous substrates. Exposure to such substrates induced B cell microvilli extension into the pores, intracellular Ca2+ signaling, phosphorylation of signaling proteins, and CD69 expression.
Nozie D. Aghaizu, Willi Weber, Nadine Strempel, Asya Polat, Enrico Klotzsch   +4 more
wiley   +1 more source

Bothrops jararacussu venom-induced neuromuscular blockade inhibited by Casearia gossypiosperma Briquet hydroalcoholic extract [PDF]

, 2015
CNPQ - CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICOFAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOThe hydroalcoholic extract of Casearia gossypiosperma Briquet (Flacourtiaceae) was standardized for the first time through ...
Camargo, T. M., Groppo, F. C., Nazato, V. S., Oshima-Franco, Y., Cogo, J. C., Silva, M. G.   +5 more
core   +1 more source

Neuromorphic Optical Tracking and Imaging of Randomly Moving Targets Through Dynamic Dense Scattering Media

Advanced Science, EarlyView.
Vision begins not with images but with change: the retina fires only when something moves, handing the brain a stream of spikes. A neuromorphic imaging system adopts the same strategy—an event sensor that sees like the retina, a spiking network that thinks like the brain—to track and reconstruct fully randomly moving targets through tissue (phantom ...
Ning Zhang, Arto Nurmikko
wiley   +1 more source

Isolation and Pharmacological Characterisation of Pre-Synaptic Neurotoxins from Thai and Javanese Russell’s Viper (Daboia siamensis) Venoms

Toxins
The widespread geographical distribution of Russell’s vipers (Daboia spp.) is associated with marked variations in the clinical outcomes of envenoming by species from different countries.
Mimi Lay, Wayne C. Hodgson
doaj   +1 more source

An Appetite for Destruction: Detecting Prey-Selective Binding of α-Neurotoxins in the Venom of Afro-Asian Elapids

Toxins, 2020
Prey-selective venoms and toxins have been documented across only a few species of snakes. The lack of research in this area has been due to the absence of suitably flexible testing platforms.
Richard J. Harris, Christina N. Zdenek, David Harrich, Nathaniel Frank, Bryan G. Fry   +4 more
doaj   +1 more source

Position of the Anaphylaxis, Insect Venom Allergy and Mastocytosis Section of the Polish Society of Allergology regarding the principles of diagnosing hypersensitivity to Hymenoptera insects venom [PDF]

Insect venom allergy is one of the most common causes of anaphylactic reactions. Proper disease diagnosis, patient qualification for treatment, education, and providing patients with a life-saving kit in case of anaphylaxis are the foundation of ...
Marta Chełmińska, Gawlik, Radosław, Nittner-Marszalska, Marita, Chełmińska, Marta, Cichocka-Jarosz, Ewa, Marek Niedoszytko, Niedoszytko, Marek, Marita Nittner-Marszalska, Andrzej Bożek, Ewa Cichocka-Jarosz, Iwona Poziomkowska-Gęsicka, Bożek, Andrzej, Poziomkowska-Gęsicka, Iwona, Radoslaw Gawlik   +13 more
core   +1 more source