Results 171 to 180 of about 119,167 (203)
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Proteome and phosphoproteome of Africanized and European honeybee venoms

PROTEOMICS, 2013
Honey bee venom toxins trigger immunological, physiological, and neurological responses within victims. The high occurrence of bee attacks involving potentially fatal toxic and allergic reactions in humans and the prospect of developing novel pharmaceuticals make honey bee venom an attractive target for proteomic studies.
Resende, Virgínia Maria Ferreira   +4 more
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Proteome and peptidome profiling of spider venoms

Expert Review of Proteomics, 2008
Spider venoms are an important source of novel molecules with different pharmacological properties. Recent technological developments of proteomics, especially mass spectrometry, have greatly promoted the systematic analysis of spider venom. The enormous diversity of venom components between spider species and the lack of complete genome sequence, and ...
openaire   +2 more sources

Activation of Bothrops jararaca snake venom gland and venom production: A proteomic approach

Journal of Proteomics, 2013
Viperidae venom glands have a basal-central lumen where the venom produced by secretory cells is stored. We have shown that the protein composition of venom gland changes during the venom production cycle. Here, we analyzed the venom gland proteins during the venom production cycle by proteomic approach. We identified specific proteins in each stage of
Milene Schmidt Luna   +4 more
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A Protein Decomplexation Strategy in Snake Venom Proteomics

2018
Snake venoms are complex mixtures of proteins and peptides that play vital roles in the survival of venomous snakes. As with their diverse pharmacological activities, snake venoms can be highly variable, hence the importance of understanding the compositional details of different snake venoms.
Choo Hock, Tan   +2 more
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Venom Genomics and Proteomics

2016
This volume provides the reader with recent advances in the fields of molecular toxinology, the biotechnological applications of venom toxins, and antivenom production. The content of the twenty chapters of Venom Genomics and Proteomics illustrates not only the enormous progress made since the implementation of omics technologies in the field of ...
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Studies on the venom proteome of Bothrops asper: Perspectives and applications

Toxicon, 2009
Bothrops asper is responsible for the vast majority of snakebite accidents in Central America and several studies have demonstrated that specific toxic and enzymatic activities of its venom vary with the geographic origin and age of the specimens. Variability in venom proteins and enzymes between specimens from the Caribbean and the Pacific versants of
Alberto, Alape-Girón   +6 more
openaire   +2 more sources

Integration of proteomic and transcriptomic data of the venom and venom gland from Tityus jaimei

Journal of Proteomics
This work presents a comprehensive transcriptomic and proteomic analysis of the venom gland and venom of Tityus jaimei, a recently described scorpion species of medical relevance in Panama and Costa Rica. High-throughput RNA sequencing (RNA-seq) and tandem mass spectrometry (MS/MS) enabled the identification of a diverse repertoire of venom proteins ...
Ana, Escobar   +7 more
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Proteomic analysis of the venom from the scorpion Mesobuthus martensii

Journal of Proteomics, 2014
The scorpion Mesobuthus martensii is the most populous species in eastern Asian countries, and several toxic components have been identified from their venoms. Nevertheless, a complete proteomic profile of the venom of M. martensii is still not available. In this study, the venom of M. martensii was analyzed by comprehensive proteomic approaches.
Xiaobo, Xu   +11 more
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Proteome and immunome of the venom of the Thai cobra, Naja kaouthia

Toxicon, 2007
The proteome of the Thai cobra, Naja kaouthia, venom, revealed by two-dimensional liquid chromatography/tandem mass spectrometry, was found to consist of peptides which could be matched with 61 proteins in the database. These proteins were classified into 12 groups according to the differences in their biological activities: cardiotoxins, cobra venom ...
Kasem, Kulkeaw   +4 more
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The protein composition of honeybee venom reconsidered by a proteomic approach

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2005
Pure honeybee venom samples were submitted to two-dimensional gel electrophoresis. A total of 49 excised spots were analyzed by mass spectrometry; 39 of them resulted in the identification of 6 different known bee venom proteins and of 3 proteins that have not been described in such samples before. The first new venom protein has a platelet-derived and
Nico, Peiren   +5 more
openaire   +2 more sources

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