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Qualitative Profiling of Venom Toxins in the Venoms of Several Bothrops Species Using High-Throughput Venomics and Coagulation Bioassaying [PDF]

open access: yesToxins
Envenoming resulting from snakebites is recognized as a priority neglected tropical disease by The World Health Organization. The Bothrops genus, consisting of different pitviper species, is considered the most medically significant taxa in Central and ...
Dimoetsha J. C. Weekers   +4 more
doaj   +3 more sources

Venomics Reveals the Venom Complexity of Sea Anemone Heteractis magnifica [PDF]

open access: yesMarine Drugs
The venoms of various sea anemones are rich in diverse toxins, which usually play a dual role in capturing prey and deterring predators. However, the complex components of such venoms have not been well known yet.
Ming Li   +7 more
doaj   +3 more sources

Next-Generation Sequencing for Venomics: Application of Multi-Enzymatic Limited Digestion for Inventorying the Snake Venom Arsenal [PDF]

open access: yesToxins, 2023
To improve the characterization of snake venom protein profiles, we report the application of a new generation of proteomic methodology to deeply characterize complex protein mixtures.
Fernanda Gobbi Amorim   +8 more
doaj   +3 more sources

Proteomic analyses of venom from a Spider Hawk, Pepsis decorata [PDF]

open access: goldJournal of Venomous Animals and Toxins including Tropical Diseases, 2023
Background: The composition of the venom from solitary wasps is poorly known, although these animals are considered sources of bioactive substances.
Matheus Nolasco   +4 more
doaj   +2 more sources

High-Throughput Venomics. [PDF]

open access: yesJ Proteome Res, 2023
In this study, we present high-throughput (HT) venomics, a novel analytical strategy capable of performing a full proteomic analysis of a snake venom within 3 days.
Slagboom J   +6 more
europepmc   +2 more sources

The Middle Eastern Cousin: Comparative Venomics of Daboia palaestinae and Daboia russelii

open access: yesToxins, 2022
Among the medically most important snakes in the world, the species belonging to the genus Daboia have been attributed to the highest number of human envenomings, deaths and disabilities.
R. R. Senji Laxme   +10 more
doaj   +2 more sources

Toxinology in the proteomics era: a review on arachnid venom proteomics [PDF]

open access: yesJournal of Venomous Animals and Toxins including Tropical Diseases, 2022
The word venomics was coined to acknowledge the studies that use omics to investigate venom proteins and peptides. Venomics has evolved considerably over the last 20 years. The first works on scorpion or spider venomics were published in the early 2000’s.
Filipi Calbaizer Marchi   +4 more
doaj   +2 more sources

Snake Venomics: Fundamentals, Recent Updates, and a Look to the Next Decade. [PDF]

open access: yesToxins (Basel), 2022
Venomic research, powered by techniques adapted from proteomics, transcriptomics, and genomics, seeks to unravel the diversity and complexity of venom through which knowledge can be applied in the treatment of envenoming, biodiscovery, and conservation ...
Tan CH.
europepmc   +2 more sources

Enlightening the toxinological dark matter of spider venom enzymes [PDF]

open access: yesnpj Biodiversity
Spiders produce highly adapted venoms featuring a complex mixture of biomolecules used mainly for hunting and defense. The most prominent components are peptidic neurotoxins, a major focus of research and drug development, whereas venom enzymes have been
Josephine Dresler   +3 more
doaj   +2 more sources

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