Results 31 to 40 of about 985 (235)

Stingray Venom Proteins: Mechanisms of Action Revealed Using a Novel Network Pharmacology Approach

Marine Drugs, 2021
Animal venoms offer a valuable source of potent new drug leads, but their mechanisms of action are largely unknown. We therefore developed a novel network pharmacology approach based on multi-omics functional data integration to predict how stingray ...
Kim N. Kirchhoff, André Billion, Christian R. Voolstra, Stephan Kremb, Thomas Wilke, Andreas Vilcinskas   +5 more
doaj   +1 more source

Proteo-Trancriptomic Analyses Reveal a Large Expansion of Metalloprotease-Like Proteins in Atypical Venom Vesicles of the Wasp Meteorus pulchricornis (Braconidae)

Toxins, 2021
Meteorus pulchricornis (Ichneumonoidea, Braconidae) is an endoparasitoid wasp of lepidopteran caterpillars. Its parasitic success relies on vesicles (named M.
Jean-Luc Gatti, Maya Belghazi, Fabrice Legeai, Marc Ravallec, Marie Frayssinet, Stéphanie Robin, Djibril Aboubakar-Souna, Ramasamy Srinivasan, Manuele Tamò, Marylène Poirié, Anne-Nathalie Volkoff   +10 more
doaj   +1 more source

Pore-Forming Proteins from Cnidarians and Arachnids as Potential Biotechnological Tools

Toxins, 2019
Animal venoms are complex mixtures of highly specialized toxic molecules. Cnidarians and arachnids produce pore-forming proteins (PFPs) directed against the plasma membrane of their target cells.
Esperanza Rivera-de-Torre, Juan Palacios-Ortega, José G. Gavilanes, Álvaro Martínez-del-Pozo, Sara García-Linares   +4 more
doaj   +1 more source

Intersexual Differences in the Gene Expression of Phoneutria depilata (Araneae, Ctenidae) Toxins Revealed by Venom Gland Transcriptome Analyses

Toxins, 2023
The wandering spider, Phoneutria depilata, is one of Colombia’s most active nocturnal arthropod predators of vertebrates and invertebrates. Its venom has been a relevant subject of study in the last two decades.
Diego Sierra Ramírez, Juan F. Alzate, Yuri Simone, Arie van der Meijden, Giovany Guevara, Lida Marcela Franco Pérez, Julio César González-Gómez, Carlos F. Prada Quiroga   +7 more
doaj   +1 more source

Qualitative Analysis of Proteins in Two Snake Venoms, Gloydius Blomhoffii and Agkistrodon Acutus

Journal of Pharmacopuncture, 2022
Objectives: Snake venom is a complex mixture of various pharmacologically active substances, such as small proteins, peptides, and organic and mineral components.
Su-Jeong Ha, Yeo-Ok Choi, Eun-Bin Kwag, Soo-Dam Kim, Hwa-seung Yoo, In-Cheol Kang, So-Jung Park   +6 more
doaj   +1 more source

Next-Generation Sequencing for Venomics: Application of Multi-Enzymatic Limited Digestion for Inventorying the Snake Venom Arsenal

Toxins, 2023
To improve the characterization of snake venom protein profiles, we report the application of a new generation of proteomic methodology to deeply characterize complex protein mixtures.
Fernanda Gobbi Amorim, Damien Redureau, Thomas Crasset, Lou Freuville, Dominique Baiwir, Gabriel Mazzucchelli, Stefanie K. Menzies, Nicholas R. Casewell, Loïc Quinton   +8 more
doaj   +1 more source

From birth to bite: the evolutionary ecology of India's medically most important snake venoms

BMC Biology
Background Snake venoms can exhibit remarkable inter- and intraspecific variation. While diverse ecological and environmental factors are theorised to explain this variation, only a handful of studies have attempted to unravel their precise roles.
R. R. Senji Laxme, Suyog Khochare, Siddharth Bhatia, Gerard Martin, Kartik Sunagar   +4 more
doaj   +1 more source

Biological Activities and Proteomic Profile of the Venom of Vipera ursinii ssp., a very Rare Karst Viper from Croatia

Toxins, 2020
The karst viper (Vipera ursinii ssp.) favours high-mountain dry grasslands in southern and south-eastern Croatia. It is medically less important than other Vipera species, because of its remote habitat and the very small amount of venom that it injects ...
Maja Lang Balija, Adrijana Leonardi, Marija Brgles, Dora Sviben, Tihana Kurtović, Beata Halassy, Igor Križaj   +6 more
doaj   +1 more source

Venomous Snakebites

Medicina, 2011
More than 5 million people are bitten by venomous snakes annually and more than 100 000 of them die. In Europe, one person dies due to envenomation every 3 years. There is only one venomous snake species in Lithuania – the common adder (Vipera berus) – which belongs to the Viperidae family; however, there are some exotic poisonous snakes in the zoos ...
Adukauskienė, Dalia, Varanauskienė, Eglė, Adukauskaitė, Agnė   +2 more
openaire   +2 more sources

Much more than their fangs: Macroscopic anatomy of the brain of Bothrops moojeni Hoge 1966 (Squamata, Serpentes, Viperidae)

The Anatomical Record, EarlyView.
Abstract Neuroanatomical research has progressed considerably in several vertebrate lineages, yet studies of reptilian brain morphology remain markedly underdeveloped. Here we provide the first description of macroscopic brain anatomy and its ontogeny in the viperid Bothrops moojeni, based on a sample of seven individuals.
Paula Araújo, Júlio César Costa de Souza, Angele Martins   +2 more
wiley   +1 more source