Results 1 to 10 of about 53,540 (244)

Neglected Venomous Animals and Toxins: Underrated Biotechnological Tools in Drug Development

open access: yesToxins, 2021
Among the vast repertoire of animal toxins and venoms selected by nature and evolution, mankind opted to devote its scientific attention—during the last century—to a restricted group of animals, leaving a myriad of toxic creatures aside.
Guilherme Rabelo Coelho   +6 more
doaj   +1 more source

Green Nanoemulsion Stabilized by In Situ Self-Assembled Natural Oil/Native Cyclodextrin Complexes: An Eco-Friendly Approach for Enhancing Anticancer Activity of Costunolide against Lung Cancer Cells

open access: yesPharmaceutics, 2022
Lung cancer is the second-most deadly malignancy worldwide, of which smoking is considered a major risk factor and causes 75–80% of lung cancer-related deaths.
Nabil A. Alhakamy   +9 more
doaj   +1 more source

Landscape of research, production, and regulation in venoms and antivenoms: a bibliometric analysis

open access: yesRevista Panamericana de Salud Pública, 2021
Objectives. To assess the productivity and visibility in research, clinical studies, treatment, use and production of antivenoms against poisonous snakes, scorpions and spiders. Methods. Bibliometric analysis of research and other activities. Articles on
José Luis Di Fabio   +2 more
doaj   +1 more source

Never, Ever Make an Enemy… Out of an Anemone: Transcriptomic Comparison of Clownfish Hosting Sea Anemone Venoms

open access: yesMarine Drugs, 2022
Sea anemones are predatory marine invertebrates and have diverse venom arsenals. Venom is integral to their biology, and is used in competition, defense, and feeding.
Alonso Delgado   +3 more
doaj   +1 more source

Therapeutic Potential of Bee and Scorpion Venom Phospholipase A2 (PLA2): A Narrative Review [PDF]

open access: yesIranian Journal of Medical Sciences, 2022
Venomous arthropods such as scorpions and bees form one of the important groups with an essential role in medical entomology. Their venom possesses a mixture of diverse compounds, such as peptides, some of which have toxic effects, and enzymatic peptide ...
Parisa Soltan-Alinejad   +3 more
doaj   +1 more source

Triple IgE-positivity to hornet, wasp and bee venom in the patient with anaphylaxis: Diagnostic and therapeutic approach [PDF]

open access: yesVojnosanitetski Pregled, 2019
Introduction. Triple-positivity (TP) or double-positivity (DP) for serum-specific immunoglobulin E (sIgE) antibodies against hornet venom (HV), wasp venom (WV) and/or honeybee venom (BV) causes significant problem in a selection of appropriate venom ...
Jovanović Dragana   +4 more
doaj   +1 more source

Discovering Venom-Derived Drug Candidates Using Differential Gene Expression

open access: yesToxins, 2023
Venoms are a diverse and complex group of natural toxins that have been adapted to treat many types of human disease, but rigorous computational approaches for discovering new therapeutic activities are scarce.
Joseph D. Romano   +6 more
doaj   +1 more source

Quo Vadis Venomics? A Roadmap to Neglected Venomous Invertebrates

open access: yesToxins, 2014
Venomics research is being revolutionized by the increased use of sensitive -omics techniques to identify venom toxins and their transcripts in both well studied and neglected venomous taxa.
Bjoern Marcus von Reumont   +2 more
doaj   +1 more source

Mass spectrometry‐based top‐down and bottom‐up approaches for proteomic analysis of the Moroccan Buthus occitanus scorpion venom

open access: yesFEBS Open Bio, 2021
Buthus occitanus (B. occitanus) is one of the most dangerous scorpions in the world. Despite the involvement of B. occitanus scorpion in severe cases of envenomation in Morocco, no study has focused yet on the proteomic composition of the Moroccan B ...
Khadija Daoudi   +8 more
doaj   +1 more source

Characterization of a Lab-Scale Process to Produce Whole IgG Antivenom Covering Scorpion Stings by Genus Tityus and Centruroides of Colombia

open access: yesPharmaceuticals, 2022
Scorpion stings are a public health event in Colombia lacking official epidemiological data, and are considered a medical emergency. Despite the two local producers of antivenoms, neither of them is currently manufacturing scorpion antivenoms. We present
Sebastian Estrada-Gomez   +4 more
doaj   +1 more source

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