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Neglected Venomous Animals and Toxins: Underrated Biotechnological Tools in Drug Development
Among the vast repertoire of animal toxins and venoms selected by nature and evolution, mankind opted to devote its scientific attention—during the last century—to a restricted group of animals, leaving a myriad of toxic creatures aside.
Guilherme Rabelo Coelho +6 more
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Lung cancer is the second-most deadly malignancy worldwide, of which smoking is considered a major risk factor and causes 75–80% of lung cancer-related deaths.
Nabil A. Alhakamy +9 more
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Landscape of research, production, and regulation in venoms and antivenoms: a bibliometric analysis
Objectives. To assess the productivity and visibility in research, clinical studies, treatment, use and production of antivenoms against poisonous snakes, scorpions and spiders. Methods. Bibliometric analysis of research and other activities. Articles on
José Luis Di Fabio +2 more
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Sea anemones are predatory marine invertebrates and have diverse venom arsenals. Venom is integral to their biology, and is used in competition, defense, and feeding.
Alonso Delgado +3 more
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Therapeutic Potential of Bee and Scorpion Venom Phospholipase A2 (PLA2): A Narrative Review [PDF]
Venomous arthropods such as scorpions and bees form one of the important groups with an essential role in medical entomology. Their venom possesses a mixture of diverse compounds, such as peptides, some of which have toxic effects, and enzymatic peptide ...
Parisa Soltan-Alinejad +3 more
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Triple IgE-positivity to hornet, wasp and bee venom in the patient with anaphylaxis: Diagnostic and therapeutic approach [PDF]
Introduction. Triple-positivity (TP) or double-positivity (DP) for serum-specific immunoglobulin E (sIgE) antibodies against hornet venom (HV), wasp venom (WV) and/or honeybee venom (BV) causes significant problem in a selection of appropriate venom ...
Jovanović Dragana +4 more
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Discovering Venom-Derived Drug Candidates Using Differential Gene Expression
Venoms are a diverse and complex group of natural toxins that have been adapted to treat many types of human disease, but rigorous computational approaches for discovering new therapeutic activities are scarce.
Joseph D. Romano +6 more
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Quo Vadis Venomics? A Roadmap to Neglected Venomous Invertebrates
Venomics research is being revolutionized by the increased use of sensitive -omics techniques to identify venom toxins and their transcripts in both well studied and neglected venomous taxa.
Bjoern Marcus von Reumont +2 more
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Buthus occitanus (B. occitanus) is one of the most dangerous scorpions in the world. Despite the involvement of B. occitanus scorpion in severe cases of envenomation in Morocco, no study has focused yet on the proteomic composition of the Moroccan B ...
Khadija Daoudi +8 more
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Scorpion stings are a public health event in Colombia lacking official epidemiological data, and are considered a medical emergency. Despite the two local producers of antivenoms, neither of them is currently manufacturing scorpion antivenoms. We present
Sebastian Estrada-Gomez +4 more
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