Snake Venoms in Drug Discovery: Valuable Therapeutic Tools for Life Saving
Toxins, 2019 Animal venoms are used as defense mechanisms or to immobilize and digest prey. In fact, venoms are complex mixtures of enzymatic and non-enzymatic components with specific pathophysiological functions.
Tarek Mohamed Abd El-Aziz +2 more
doaj +2 more sources
Evaluation of the Lethal Potency of Scorpion and Snake Venoms and Comparison between Intraperitoneal and Intravenous Injection Routes [PDF]
Toxins, 2014 Scorpion stings and snake bites are major health hazards that lead to suffering of victims and high mortality. Thousands of injuries associated with such stings and bites of venomous animals occur every year worldwide.
Naoual Oukkache +6 more
doaj +4 more sources
Centipede venoms as a source of drug leads [PDF]
Expert Opinion on Drug Discovery, 2016 peerreview_statement: The publishing and review policy for this title is described in its Aims & Scope. aims_and_scope_url: http://www.tandfonline.com/action/journalInformation?show=aimsScope&journalCode=iedc20© 2016 Taylor and Francis.
de la Vega RC +6 more
core +2 more sources
Comparative Analysis of the Enzymatic, Coagulant, and Neuromuscular Activities of Two Variants of Crotalus durissus ruruima Venom and Antivenom Efficacy [PDF]
PharmaceuticalsBackground: We compared the enzymatic, coagulant, and neuromuscular activities of two variants (yellow—CDRy and white—CDRw) of Crotalus durissus ruruima venom with a sample of C. d.
Poliana J. Demico +17 more
doaj +2 more sources
A polygeneric immunogen composed of 22 venoms from sub-Saharan African snakes to expand the neutralization scope of the EchiTAb-plus-ICP antivenom [PDF]
Toxicon: XRecent research suggests that a polygeneric immunogen made from the venoms of the most medically important viperid and elapid snakes in sub-Saharan Africa could elicit a broader antibody response in horses compared to the current EchiTAb-plus-ICP ...
Andrés Sánchez +16 more
doaj +2 more sources
What Are the Neurotoxins in Hemotoxic Snake Venoms?
International Journal of Molecular Sciences, 2023 Snake venoms as tools for hunting are primarily aimed at the most vital systems of the prey, especially the nervous and circulatory systems. In general, snakes of the Elapidae family produce neurotoxic venoms comprising of toxins targeting the nervous ...
A. Osipov, Y. Utkin
semanticscholar +1 more source
Neglected Venomous Animals and Toxins: Underrated Biotechnological Tools in Drug Development
Toxins, 2021 Among the vast repertoire of animal toxins and venoms selected by nature and evolution, mankind opted to devote its scientific attention—during the last century—to a restricted group of animals, leaving a myriad of toxic creatures aside.
Guilherme Rabelo Coelho +6 more
doaj +1 more source
Bioactive Peptides and Proteins from Wasp Venoms
Biomolecules, 2022 Wasps, members of the order Hymenoptera, use their venom for predation and defense. Accordingly, their venoms contain various constituents acting on the circulatory, immune and nervous systems.
Lei Luo, P. Kamau, R. Lai
semanticscholar +1 more source
The biology and evolution of spider venoms
Biological Reviews of The Cambridge Philosophical Society, 2021 Spiders are diverse, predatory arthropods that have inhabited Earth for around 400 million years. They are well known for their complex venom systems that are used to overpower their prey.
Tim Lüddecke +3 more
semanticscholar +1 more source
Phylogenetically diverse diets favor more complex venoms in North American pitvipers
Proceedings of the National Academy of Sciences of the United States of America, 2021 Significance Why biological complexity evolves is a major question in the life sciences, but the specific selection pressures favoring simple or complex traits remain unclear.
M. Holding +22 more
semanticscholar +1 more source