What Are the Neurotoxins in Hemotoxic Snake Venoms?
International Journal of Molecular Sciences, 2023 Snake venoms as tools for hunting are primarily aimed at the most vital systems of the prey, especially the nervous and circulatory systems. In general, snakes of the Elapidae family produce neurotoxic venoms comprising of toxins targeting the nervous ...
A. Osipov, Y. Utkin
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The biology and evolution of spider venoms
Biological Reviews of The Cambridge Philosophical Society, 2021 Spiders are diverse, predatory arthropods that have inhabited Earth for around 400 million years. They are well known for their complex venom systems that are used to overpower their prey.
Tim Lüddecke +3 more
semanticscholar +1 more source
Phylogenetically diverse diets favor more complex venoms in North American pitvipers
Proceedings of the National Academy of Sciences of the United States of America, 2021 Significance Why biological complexity evolves is a major question in the life sciences, but the specific selection pressures favoring simple or complex traits remain unclear.
M. Holding +22 more
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Frontiers in Pharmacology, 2020 Animal poisons and venoms are comprised of different classes of molecules displaying wide-ranging pharmacological activities. This review aims to provide an in-depth view of toxin-based compounds from terrestrial and marine organisms used as diagnostic ...
Karla C F Bordon +15 more
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Therapeutic Potential of Bee and Scorpion Venom Phospholipase A2 (PLA2): A Narrative Review [PDF]
Iranian Journal of Medical Sciences, 2022 Venomous arthropods such as scorpions and bees form one of the important groups with an essential role in medical entomology. Their venom possesses a mixture of diverse compounds, such as peptides, some of which have toxic effects, and enzymatic peptide ...
Parisa Soltan-Alinejad +3 more
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Snake Venomics and Antivenomics of Bothrops diporus, a Medically Important Pitviper in Northeastern Argentina [PDF]
, 2015 Snake species within genus Bothrops are responsible for more than 80% of the snakebites occurring in South America. The species that cause most envenomings in Argentina, B.
Calvete, Juan J. +3 more
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Repurposing cancer drugs, batimastat and marimastat, to inhibit the activity of a group I metalloprotease from the venom of the Western Diamondback rattlesnake, Crotalus atrox [PDF]
, 2020 Snakebite envenomation causes over 140,000 deaths every year predominantly in developing countries. As a result, it is one of the most lethal neglected tropical diseases.
Bicknell, Andrew B. +12 more
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Triple IgE-positivity to hornet, wasp and bee venom in the patient with anaphylaxis: Diagnostic and therapeutic approach [PDF]
Vojnosanitetski Pregled, 2019 Introduction. Triple-positivity (TP) or double-positivity (DP) for serum-specific immunoglobulin E (sIgE) antibodies against hornet venom (HV), wasp venom (WV) and/or honeybee venom (BV) causes significant problem in a selection of appropriate venom ...
Jovanović Dragana +4 more
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Toxins, 2020 The phospholipase A2 (PLA2) inhibitor Varespladib (LY315920) and its orally bioavailable prodrug, methyl-Varespladib (LY333013) inhibit PLA2 activity of a wide variety of snake venoms.
J. Gutiérrez +3 more
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Discovering Venom-Derived Drug Candidates Using Differential Gene Expression
Toxins, 2023 Venoms are a diverse and complex group of natural toxins that have been adapted to treat many types of human disease, but rigorous computational approaches for discovering new therapeutic activities are scarce.
Joseph D. Romano +6 more
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