Does the traditional snakebite severity score correctly classify envenomated patients? [PDF]
Clinical and Experimental Emergency Medicine, 2016 Objective This study aims to help set domestic guidelines for administration of antivenom to envenomated patients after snakebites. Methods This retrospective observational case series comprised 128 patients with snake envenomation.
Seungho Kang +2 more
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Harnessing the Power of Venomous Animal-Derived Toxins against COVID-19
Toxins, 2023 Animal-derived venoms are complex mixtures of toxins triggering important biological effects during envenomings. Although venom-derived toxins are known for their potential of causing harm to victims, toxins can also act as pharmacological agents. During
Isadora Oliveira +8 more
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Purification of a fragment obtained by autolysis of a PIIIb-SVMP from Bothrops alternatus venom [PDF]
, 2018 Snake Venom Metalloproteinases (SVMPs) represent 43.1% of the components in Bothrops alternatus venom and play an important role in envenomation. Disintegrins and disintegrin-like domains are released by proteolytic processing of PII and PIII classes of ...
Acosta, Ofelia Cristina +9 more
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Tissue Localization and Extracellular Matrix Degradation by PI, PII and PIII Snake Venom Metalloproteinases: Clues on the Mechanisms of Venom-Induced Hemorrhage [PDF]
, 2015 20 páginas, 4 figuras, 3 tablas y 7 tablas en material suplementario.Snake venom hemorrhagic metalloproteinases (SVMPs) of the PI, PII and PIII classes were compared in terms of tissue localization and their ability to hydrolyze basement membrane ...
A Osaka +52 more
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Expression of the First Recombinant Anti-Tumoral Snake Venom Kunitz-Type Serine Protease Inhibitor
Toxins, 2022 PIVL is a Kunitz-type serine protease inhibitor that was previously characterized from Tunisian snake venom, Macrovipera lebetina transmediterranea. It reduced glioblastoma cells’ development and significantly blocked angiogenesis in in-vitro and ex-vivo
Maram Morjen +6 more
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Concanavalin A-Binding Enzymes of Crotalus scutulatus scutulatus Venom [PDF]
, 1985 Crotalus scutulatus scutulatus crude venom was separated into two fractions by Concanavalin A Sepharose 4B affinity chromatography. The proteins binding to Con A exhibited phosphomonoesterase (orthophosphoric monoester phosphohydrolase EC 3.1.3.2 ...
Childs, C. K. +3 more
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Are ticks venomous animals? [PDF]
Frontiers in Zoology, 2014 As an ecological adaptation venoms have evolved independently in several species of Metazoa. As haematophagous arthropods ticks are mainly considered as ectoparasites due to directly feeding on the skin of animal hosts. Ticks are of major importance since they serve as vectors for several diseases affecting humans and livestock animals.
Cabezas Cruz, Alejandro +1 more
openaire +5 more sources
Dramatic expansion of the black widow toxin arsenal uncovered by multi-tissue transcriptomics and venom proteomics. [PDF]
, 2014 BackgroundAnimal venoms attract enormous interest given their potential for pharmacological discovery and understanding the evolution of natural chemistries.
Ayoub, Nadia A +4 more
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Curcumin Attenuated Neurotoxicity in Sporadic Animal Model of Alzheimer’s Disease
Molecules, 2021 Alzheimer’s disease (AD) is one of the most common neurodegenerative diseases leading to dementia. Despite research efforts, currently there are no effective pharmacotherapeutic options for the prevention and treatment of AD.
Ines ELBini-Dhouib +5 more
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