Results 41 to 50 of about 91,600 (240)

The assassin bug Pristhesancus plagipennis produces two distinct venoms in separate gland lumens

open access: yesNature Communications, 2018
The assassin bug venom system plays diverse roles in prey capture, defence and extra-oral digestion, but it is poorly characterised, partly due to its anatomical complexity.
A. Walker   +8 more
semanticscholar   +1 more source

Secreted Phospholipases A2 of Snake Venoms: Effects on the Peripheral Neuromuscular System with Comments on the Role of Phospholipases A2 in Disorders of the CNS and Their Uses in Industry

open access: yesToxins, 2013
Neuro- and myotoxicological signs and symptoms are significant clinical features of envenoming snakebites in many parts of the world. The toxins primarily responsible for the neuro and myotoxicity fall into one of two categories—those that bind to and ...
John B. Harris, Tracey Scott-Davey
doaj   +1 more source

Snake Venoms in Cancer Therapy: Past, Present and Future

open access: yesToxins, 2018
Cancer is one of the leading causes of morbidity and mortality worldwide, and the discovery of new drugs for cancer therapy is one of the most important objectives for the pharmaceutical industry.
Li Li, Jianzhong Huang, Yao Lin
semanticscholar   +1 more source

Two related thrombin-like enzymes present in Bothrops atrox venom

open access: yesBrazilian Journal of Medical and Biological Research, 2000
This article describes the presence of two new forms of a thrombin-like enzyme, both with apparent molecular masses of 38 kDa, in Bothrops atrox venom. Both share the ability to cleave fibrinogen into fibrin and to digest casein.
J.H. Petretski   +4 more
doaj   +1 more source

Expression of the First Recombinant Anti-Tumoral Snake Venom Kunitz-Type Serine Protease Inhibitor

open access: yesToxins, 2022
PIVL is a Kunitz-type serine protease inhibitor that was previously characterized from Tunisian snake venom, Macrovipera lebetina transmediterranea. It reduced glioblastoma cells’ development and significantly blocked angiogenesis in in-vitro and ex-vivo
Maram Morjen   +6 more
doaj   +1 more source

PROTEINS OF PAROTOID GLAND SECRETIONS FROM TOADS OF THE GENUS BUFO [PDF]

open access: yes, 2000
Freeze-dried parotoid gland secretions from toads of the genus Bufo contained large proportions of protein (25-35% by weight). SDS-PAGE suggested that secretions from several species of Bufo contained mixtures of proteins in the relative molecular mass ...
Perry, David
core   +2 more sources

A C-type lectin from Bothrops jararacussu venom can adhere to extracellular matrix proteins and induce the rolling of leukocytes

open access: yesJournal of Venomous Animals and Toxins including Tropical Diseases, 2007
Purification of a lectin from Bothrops jararacussu venom (BjcuL) was carried out using agarose-D-galactose affinity gel. MALDI-TOF gave a major signal at m/z 32028, suggesting the presence of a dimmer composed of two identical subunits.
S. L. Elífio-Esposito   +8 more
doaj   +1 more source

The envenomation of general physiology throughout the last century. [PDF]

open access: yes, 2017
Toxins are the poisonous products of organisms. Toxins serve vital defensive and offensive functions for those that harbor them: stinging scorpions, pesticidal plants, sanguinary snakes, fearless frogs, sliming snails, noxious newts, and smarting spiders.
Sack, Jon T
core   +1 more source

Spider venom administration impairs glioblastoma growth and modulates immune response in a non-clinical model. [PDF]

open access: yes, 2020
Molecules from animal venoms are promising candidates for the development of new drugs. Previous in vitro studies have shown that the venom of the spider Phoneutria nigriventer (PnV) is a potential source of antineoplastic components with activity in ...
Barreto, Natália   +12 more
core   +1 more source

Histopathological analysis and in situ localisation of Australian tiger snake venom in two clinically envenomed domestic animals [PDF]

open access: yes, 2011
Objective: To assess histopathological changes in clinically envenomed tiger snake patients and identify tissue specific localisation of venom toxins using immunohistochemistry.
Balmer, L.   +5 more
core   +2 more sources

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