Research progress on the pathogenesis and treatment of ventilator-induced diaphragm dysfunction [PDF]
Heliyon, 2023 Prolonged controlled mechanical ventilation (CMV) can cause diaphragm fiber atrophy and inspiratory muscle weakness, resulting in diaphragmatic contractile dysfunction, called ventilator-induced diaphragm dysfunction (VIDD).
Jumei Zhang +5 more
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Increased SOD2 in the diaphragm contributes to exercise-induced protection against ventilator-induced diaphragm dysfunction [PDF]
Redox Biology, 2019 Mechanical ventilation (MV) is a life-saving intervention for many critically ill patients. Unfortunately, prolonged MV results in rapid diaphragmatic atrophy and contractile dysfunction, collectively termed ventilator-induced diaphragm dysfunction (VIDD)
Aaron B. Morton +11 more
doaj +7 more sources
Angiotensin 1‐7 protects against ventilator‐induced diaphragm dysfunction [PDF]
Clinical and Translational Science, 2021 Mechanical ventilation (MV) is a life‐saving instrument used to provide ventilatory support for critically ill patients and patients undergoing surgery.
Toshinori Yoshihara +5 more
doaj +5 more sources
Altered expression of microRNAs in the rat diaphragm in a model of ventilator-induced diaphragm dysfunction after controlled mechanical ventilation [PDF]
BMC Genomics, 2021 Background Ventilator-induced diaphragm dysfunction (VIDD) is a common complication of life support by mechanical ventilation observed in critical patients in clinical practice and may predispose patients to severe complications such as ventilator ...
Pengcheng Wang +5 more
doaj +5 more sources
Ventilator-induced diaphragm dysfunction: translational mechanisms lead to therapeutical alternatives in the critically ill [PDF]
Intensive Care Medicine Experimental, 2019 Mechanical ventilation [MV] is a life-saving technique delivered to critically ill patients incapable of adequately ventilating and/or oxygenating due to respiratory or other disease processes.
Oscar Peñuelas +6 more
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Comparative Efficacy of Angiotensin II Type 1 Receptor Blockers Against Ventilator‐Induced Diaphragm Dysfunction in Rats [PDF]
Clinical and Translational Science, 2021 Mechanical ventilation (MV) is a life‐saving intervention for many critically ill patients. Unfortunately, prolonged MV results in the rapid development of inspiratory muscle weakness due to diaphragmatic atrophy and contractile dysfunction (termed ...
Stephanie E. Hall +8 more
doaj +2 more sources
Rehabilitating the diaphragm: an integrated approach to intensive care unit-acquired dysfunction in critical illness—a narrative review [PDF]
Acute and Critical CareImproved survival in critical illness has increased recognition of intensive care unit (ICU) complications, particularly ICU-acquired weakness, which affects up to 25% of patients. Diaphragm involvement is common and contributes to prolonged ventilation,
Ricardo Arriagada +7 more
doaj +2 more sources
Mechanosensitive Piezo1 Channels Mediate Diaphragm Fibrosis Induced by Prolonged Mechanical Ventilation [PDF]
Journal of Cachexia, Sarcopenia and MuscleBackground Ventilator‐induced diaphragmatic dysfunction (VIDD) is a major complication in critically ill patients. Prolonged mechanical ventilation (MV) triggers diaphragmatic fibrotic remodelling, but the underlying mechanisms remain unclear. This study
Dan Xie +9 more
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Non‐invasive phrenic nerve stimulation to avoid ventilator‐induced diaphragm dysfunction in critical care [PDF]
Artificial Organs, 2022 , Conor Keogh, Britam Gomez
exaly +2 more sources
Frontiers in Physiology, 2016 Intensive care unit (ICU) patients are often overtly subjected to mechanical ventilation and immobilization, which leads to impaired limb and respiratory muscle function.
Hannah Ogilvie +5 more
doaj +3 more sources