Research progress on the pathogenesis and treatment of ventilator-induced diaphragm dysfunction [PDF]
Heliyon, 2023 Prolonged controlled mechanical ventilation (CMV) can cause diaphragm fiber atrophy and inspiratory muscle weakness, resulting in diaphragmatic contractile dysfunction, called ventilator-induced diaphragm dysfunction (VIDD).
Jumei Zhang +5 more
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Increased SOD2 in the diaphragm contributes to exercise-induced protection against ventilator-induced diaphragm dysfunction [PDF]
Redox Biology, 2019 Mechanical ventilation (MV) is a life-saving intervention for many critically ill patients. Unfortunately, prolonged MV results in rapid diaphragmatic atrophy and contractile dysfunction, collectively termed ventilator-induced diaphragm dysfunction (VIDD)
Aaron B. Morton +11 more
doaj +4 more sources
Altered expression of microRNAs in the rat diaphragm in a model of ventilator-induced diaphragm dysfunction after controlled mechanical ventilation [PDF]
BMC Genomics, 2021 Background Ventilator-induced diaphragm dysfunction (VIDD) is a common complication of life support by mechanical ventilation observed in critical patients in clinical practice and may predispose patients to severe complications such as ventilator ...
Pengcheng Wang +5 more
doaj +2 more sources
Angiotensin 1‐7 protects against ventilator‐induced diaphragm dysfunction [PDF]
Clinical and Translational Science, 2021 Mechanical ventilation (MV) is a life‐saving instrument used to provide ventilatory support for critically ill patients and patients undergoing surgery.
Toshinori Yoshihara +5 more
doaj +2 more sources
Combatting ventilator induced diaphragm dysfunction with human bone marrow mesenchymal stromal cell-derived extracellular vesicles [PDF]
Skeletal MuscleBackground Prolonged mechanical ventilation is closely associated with ventilator-induced lung injury (VILI) and ventilator-induced diaphragm dysfunction (VIDD).
Ya Wen +9 more
doaj +2 more sources
Ventilator-induced diaphragm dysfunction: translational mechanisms lead to therapeutical alternatives in the critically ill [PDF]
Intensive Care Medicine Experimental, 2019 Mechanical ventilation [MV] is a life-saving technique delivered to critically ill patients incapable of adequately ventilating and/or oxygenating due to respiratory or other disease processes.
Oscar Peñuelas +6 more
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Applying lessons from limb muscle disuse and ageing to better understand ventilator-induced diaphragm dysfunction. [PDF]
Exp PhysiolAbstract Mechanical ventilation (MV) is a life‐saving intervention applied to critically ill patients. A common consequence of MV is ventilator‐induced diaphragm dysfunction (VIDD), which is characterized by significant diaphragm atrophy and reduced contractile function. Older patients who receive MV are more likely to develop VIDD, have worse recovery,
Mesquita PHC +3 more
europepmc +2 more sources
Comparative Efficacy of Angiotensin II Type 1 Receptor Blockers Against Ventilator‐Induced Diaphragm Dysfunction in Rats [PDF]
Clinical and Translational Science, 2021 Mechanical ventilation (MV) is a life‐saving intervention for many critically ill patients. Unfortunately, prolonged MV results in the rapid development of inspiratory muscle weakness due to diaphragmatic atrophy and contractile dysfunction (termed ...
Stephanie E. Hall +8 more
doaj +2 more sources
Frontiers in Physiology, 2016 Intensive care unit (ICU) patients are often overtly subjected to mechanical ventilation and immobilization, which leads to impaired limb and respiratory muscle function.
Hannah Ogilvie +5 more
doaj +3 more sources
Non‐invasive phrenic nerve stimulation to avoid ventilator‐induced diaphragm dysfunction in critical care [PDF]
Artificial Organs, 2022 Conor Keogh, Britam Gomez
exaly +2 more sources