Identification of key genes affecting ventilator-induced diaphragmatic dysfunction in diabetic mice [PDF]
BackgroundMechanical ventilation (MV) is often required in critically ill patients. However, prolonged mechanical ventilation can lead to Ventilator-induced diaphragmatic dysfunction (VIDD), resulting in difficulty in extubation after tracheal intubation,
Rongchun Xing +11 more
doaj +6 more sources
Treatment with levosimendan in an experimental model of early ventilator-induced diaphragmatic dysfunction [PDF]
Introduction: Mechanical ventilation (MV) is a life-saving approach in critically ill patients. However, it may affect the diaphragmatic structure and function, beyond the lungs.
Vanessa Zambelli +6 more
doaj +6 more sources
Hypercapnia and ventilator-induced diaphragmatic dysfunction. [PDF]
In the previous issue of Critical Care, Jung and colleagues report on the preventive effects of hypercapnia on ventilator-induced diaphragmatic dysfunction (VIDD) under controlled ventilation. Possibly, a combination of controlled hypercapnia and allowed spontaneous breathing efforts may provide complementary protection for diaphragm and respiratory ...
Akca O, Bautista A.
europepmc +3 more sources
Transcriptome profiling of the diaphragm in a controlled mechanical ventilation model reveals key genes involved in ventilator-induced diaphragmatic dysfunction [PDF]
Background Ventilator-induced diaphragmatic dysfunction (VIDD) is associated with weaning difficulties, intensive care unit hospitalization (ICU), infant mortality, and poor long-term clinical outcomes.
Ruining Liu +5 more
doaj +2 more sources
Outcomes in critically ill patients after diaphragmatic stimulation on ventilator-induced diaphragmatic dysfunction: a systematic review. [PDF]
Mechanical ventilation (MV) is a lifesaving procedure for critically ill patients. Diaphragm activation and stimulation may counteract side effects, such as ventilator-induced diaphragm dysfunction (VIDD). The effects of stimulation on diaphragm atrophy and patient outcomes are reported in this systematic review.Studies investigating diaphragmatic ...
Panelli A +5 more
europepmc +3 more sources
Background and Aims Mechanical ventilation is associated with several risks, including barotrauma, ventilator‐associated pneumonia, and ventilator‐induced diaphragmatic dysfunction.
Naonori Tashiro +6 more
doaj +2 more sources
Angiotensin-(1–7) exerts a protective action in a rat model of ventilator-induced diaphragmatic dysfunction [PDF]
Background Ventilator-induced diaphragmatic dysfunction (VIDD) is a common event during mechanical ventilation (MV) leading to rapid muscular atrophy and contractile dysfunction. Recent data show that renin-angiotensin system is involved in diaphragmatic
Vanessa Zambelli +7 more
doaj +2 more sources
Ventilator-Induced Diaphragmatic Dysfunction: Diagnosis and Role of Pharmacological Agents [PDF]
The use of controlled mechanical ventilation results in a major reduction of diaphragmatic contractile force together with atrophy of diaphragm muscle fibers, which is a condition known as ventilator-induced diaphragmatic dysfunction. Ventilator-induced diaphragmatic dysfunction is one of the major contributors to weaning difficulties and even ...
Chae-Man Lim, Won-Young Kim
exaly +3 more sources
Phrenic nerve stimulation to prevent diaphragmatic dysfunction and ventilator-induced lung injury
Side effects of mechanical ventilation, such as ventilator-induced diaphragmatic dysfunction (VIDD) and ventilator-induced lung injury (VILI), occur frequently in critically ill patients.
Alessandro Panelli +4 more
doaj +3 more sources
Objectives: This study aimed to investigate the effect of noise control care on emotional state and sleep quality in patients with ventilator-induced diaphragmatic dysfunction (VIDD).
ZhiYun Qiu, Wei Zhang, ZhuLin Yan
doaj +2 more sources

