Results 11 to 20 of about 3,855 (162)

Mechanosensitive Piezo1 Channels Mediate Diaphragm Fibrosis Induced by Prolonged Mechanical Ventilation [PDF]

Journal of Cachexia, Sarcopenia and Muscle
Background Ventilator‐induced diaphragmatic dysfunction (VIDD) is a major complication in critically ill patients. Prolonged mechanical ventilation (MV) triggers diaphragmatic fibrotic remodelling, but the underlying mechanisms remain unclear. This study
Dan Xie, Yuru Xiao, Xuexin Li, Bowen Sun, Jianguo Feng, Jing Jia, Jie Li, Yun Wang, Fei He, Li Liu   +9 more
doaj   +2 more sources

Adaptive Support Ventilation Prevents Ventilator-induced Diaphragmatic Dysfunction in Piglet [PDF]

Anesthesiology, 2010
Background Contrary to adaptive support ventilation (ASV), prolonged totally controlled mechanical ventilation (CMV) results in the absence of diaphragm activity and causes ventilator-induced diaphragmatic dysfunction.
Gerald Chanques, Samir Jaber, Basil Petrof   +2 more
exaly   +4 more sources

MRI Assessment of Global and Regional Diaphragmatic Motion in Critically Ill Patients Following Prolonged Ventilator Weaning

Medical Sciences, 2019
Introduction: diaphragmatic dysfunction is a common cause of slow weaning in mechanically ventilated patients. Diaphragmatic dysfunction in ventilated patients can be global or regional.
Khurram Saleem Khan, James Meaney, Ignacio Martin-Loeches, Daniel V. Collins   +3 more
doaj   +3 more sources

Ventilator-induced diaphragmatic dysfunction: pathophysiology, monitoring and advances in potential treatment and prevention

European Respiratory Review
Mechanical ventilation is a life-saving method for those critically ill patients with acute or chronic respiratory failure without assistance. However, even short-term mechanical ventilation can lead to alterations in the fibrous structure and reduced ...
Wei Fu, Lili Guan, Qi Liu, Zhefan Xie, Junting You, Rongchang Chen   +5 more
doaj   +3 more sources

Ventilator-induced Diaphragmatic Dysfunction in Patients with Traumatic Brain Injury

Journal of Neuroanaesthesiology and Critical Care, 2023
Parmod K. Bithal, Girija P. Rath
doaj   +2 more sources

Identification of competing endogenous RNA networks involved in phrenic nerve stimulation preventing mechanical ventilation induced diaphragm dysfunction [PDF]

Scientific Reports
Ventilator-induced diaphragmatic dysfunction (VIDD) is characterized by diaphragmatic atrophy and contractile failure, leading to prolonged intensive care unit (ICU) stays and increases mortality.
Mingming Zhang, Fangyuan Li, Min Wang, Lei Li, Wenyan Hao, Xuejiao Duan, Dong Zhang   +6 more
doaj   +2 more sources

Commentary on 'Irisin Attenuates Ventilator-Induced Diaphragmatic Dysfunction by Inhibiting Endoplasmic Reticulum Stress Through Activation of AMPK'. [PDF]

J Cell Mol Med
Journal of Cellular and Molecular Medicine, Volume 30, Issue 11, June 2026.
Li W, Yang H, Li J, Xu X.
europepmc   +2 more sources

Inspiratory Muscle Training Prevents Diaphragmatic Atrophy in Mechanically Ventilated COVID-19 Patients [PDF]

International Journal of Medical Arts, 2021
Background: Unloading the diaphragm by mechanical ventilation results in diaphragmatic dysfunction and atrophy, a condition recognized in critical care settings as ventilator-induced diaphragmatic dysfunction (VIDD).
Toqa El Naggar, Hany Obaya, Azza Ismail, Rashida Azzam, Abdulrahman El Naggar   +4 more
doaj   +1 more source

Irisin attenuates ventilator-induced diaphragmatic dysfunction by inhibiting endoplasmic reticulum stress through activation of AMPK. [PDF]

J Cell Mol Med
Zhang J, Tu R, Guan F, Feng J, Jia J, Zhou J, Wang X, Liu L.   +7 more
europepmc   +2 more sources

Research progress on the pathogenesis and treatment of ventilator-induced diaphragm dysfunction

Heliyon, 2023
Prolonged controlled mechanical ventilation (CMV) can cause diaphragm fiber atrophy and inspiratory muscle weakness, resulting in diaphragmatic contractile dysfunction, called ventilator-induced diaphragm dysfunction (VIDD).
Jumei Zhang, Jianguo Feng, Jing Jia, Xiaobin Wang, Jun Zhou, Li Liu   +5 more
doaj   +1 more source