Results 21 to 30 of about 3,855 (162)

Late Ventilator-Induced Diaphragmatic Dysfunction After Extubation [PDF]

Critical Care Medicine, 2020
Objectives: Mechanical ventilation is associated with primary diaphragmatic dysfunction, also termed ventilator-induced diaphragmatic dysfunction. Studies evaluating diaphragmatic function recovery after extubation are lacking.
Dridi, Haikel, Jung, Boris, Yehya, Mohamad, Daurat, Aurelien, Reiken, Steven, Moreau, Johan, Marks, Andrew, Matecki, Stefan, Lacampagne, Alain, Jaber, Samir   +9 more
openaire   +2 more sources

Hydrogen sulfide donor protects against mechanical ventilation‐induced atrophy and contractile dysfunction in the rat diaphragm

Clinical and Translational Science, 2021
Mechanical ventilation (MV) is a clinical tool providing adequate alveolar ventilation in patients that require respiratory support. Although a life‐saving intervention for critically ill patients, prolonged MV results in the rapid development of ...
Noriko Ichinoseki‐Sekine, Ashley J. Smuder, Aaron B. Morton, James M. Hinkley, Andres Mor Huertas, Scott K. Powers   +5 more
doaj   +1 more source

PINK1/Parkin-mediated mitophagy in mechanical ventilation-induced diaphragmatic dysfunction [PDF]

Therapeutic Advances in Respiratory Disease, 2021
Background: Mechanical ventilation (MV) often leads to ventilation-induced diaphragm dysfunction (VIDD). Although the development of this disorder had been linked to oxidative stress, mitochondrial energy deficiency, autophagy activation, and apoptosis in the diaphragm, it remains unclear whether the activation of mitophagy can induce VIDD.
Hui Yong, Yun Zhou, Wanlin Ye, Tianmei Li, Gangming Wu, Jingyuan Chen, Li Liu, Jicheng Wei   +7 more
openaire   +3 more sources

Temporary diaphragm pacing for patients at risk of prolonged mechanical ventilation after extensive aortic repair

Journal of Vascular Surgery Cases and Innovative Techniques, 2023
Objective: Prolonged mechanical ventilation (MV) after extensive aortic reconstructive surgery is common. Studies have demonstrated that diaphragm pacing (DP) improves lung function in patients with unilateral diaphragm paralysis.
Jane M. Chung, MD, Aric A. Wogsland, MD, Saideep Bose, MD, Robert Schilz, DO, Raymond P. Onders, MD, Jae S. Cho, MD   +5 more
doaj   +1 more source

Ventilator‐induced diaphragmatic dysfunction in MDX mice [PDF]

Muscle & Nerve, 2017
ABSTRACTIntroductionPatients with Duchenne muscular dystrophy (DMD) frequently undergo mechanical ventilation (MV) for treatment of hypoventilation, but the susceptibility of the dystrophic diaphragm to ventilator‐induced diaphragmatic dysfunction (VIDD) has not been examined.MethodsDystrophic mice (mdx—genetic homolog of DMD) were assigned to non ...
Liang, Feng, Li, Tong, Azuelos, Ilan, Giordano, Christian, Liang, Han, Hussain, Sabah, Matecki, Stefan, Petrof, Basil   +7 more
openaire   +3 more sources

Disturbances in Calcium Homeostasis Promotes Skeletal Muscle Atrophy: Lessons From Ventilator-Induced Diaphragm Wasting

Frontiers in Physiology, 2020
Mechanical ventilation (MV) is often a life-saving intervention for patients in respiratory failure. Unfortunately, a common and undesired consequence of prolonged MV is the development of diaphragmatic atrophy and contractile dysfunction.
Hayden W. Hyatt, Scott K. Powers
doaj   +1 more source

Recovery of diaphragm function following mechanical ventilation in a rodent model. [PDF]

PLoS ONE, 2014
BACKGROUND: Mechanical ventilation (MV) induces diaphragmatic muscle fiber atrophy and contractile dysfunction (ventilator induced diaphragmatic dysfunction, VIDD).
Christian S Bruells, Ingmar Bergs, Rolf Rossaint, Jun Du, Christian Bleilevens, Andreas Goetzenich, Joachim Weis, Michael P Wiggs, Scott K Powers, Marc Hein   +9 more
doaj   +1 more source

Patient-Ventilator Dyssynchrony [PDF]

Korean Journal of Critical Care Medicine, 2017
In mechanically ventilated patients, assisted mechanical ventilation (MV) is employed early, following the acute phase of critical illness, in order to eliminate the detrimental effects of controlled MV, most notably the development of ventilator-induced
Elvira-Markela Antonogiannaki, Dimitris Georgopoulos, Evangelia Akoumianaki   +2 more
doaj   +1 more source

First non-invasive magnetic phrenic nerve and diaphragm stimulation in anaesthetized patients: a proof-of-concept study

Intensive Care Medicine Experimental, 2023
Background Mechanical ventilation has side effects such as ventilator-induced diaphragm dysfunction, resulting in prolonged intensive care unit length of stays.
Alessandro Panelli, Hermann Georges Bartels, Sven Krause, Michael André Verfuß, Aline Michèle Grimm, Niklas Martin Carbon, Julius J. Grunow, Diego Stutzer, Thomas Niederhauser, Laurent Brochard, Steffen Weber-Carstens, Stefan J. Schaller   +11 more
doaj   +1 more source

Increased SOD2 in the diaphragm contributes to exercise-induced protection against ventilator-induced diaphragm dysfunction

Redox Biology, 2019
Mechanical ventilation (MV) is a life-saving intervention for many critically ill patients. Unfortunately, prolonged MV results in rapid diaphragmatic atrophy and contractile dysfunction, collectively termed ventilator-induced diaphragm dysfunction (VIDD)
Aaron B. Morton, Ashley J. Smuder, Michael P. Wiggs, Stephanie E. Hall, Bumsoo Ahn, J. Matthew Hinkley, Noriko Ichinoseki-Sekine, Andres Mor Huertas, Mustafa Ozdemir, Toshinori Yoshihara, Nicholas R. Wawrzyniak, Scott K. Powers   +11 more
doaj   +1 more source