Results 91 to 100 of about 80,362 (282)

Functional Characterization of the Cat and Dog Wild‐Type and Mutant MDR1 Carrier Proteins and Frequency of the MDR1 Gene Mutation in 800 Cats From Germany

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT The ATP‐binding cassette transporter MDR1 P‐glycoprotein (syn. ABCB1) is an efflux carrier at the cell membrane that regulates drug absorption, distribution, and elimination. At the blood–brain barrier, MDR1 restricts brain entry of potentially neurotoxic drugs, such as ivermectin. In dogs and cats, MDR1 (syn.
Lisa Siegl, Mies Bethäuser, Daniela Nürnberger, Stefan Oswald, Andreas Moritz, Melanie Hamann, Joachim Geyer   +6 more
wiley   +1 more source

Verapamil

, 2006
europepmc   +2 more sources

Characterization of a monoclonal antibody that induces the acrosome reaction of sea urchin sperm. [PDF]

, 1987
A monoclonal antibody, J18/29, induces the acrosome reaction (AR) in spermatozoa of the sea urchin Strongylocentrotus purpuratus. J18/29 induces increases in both intracellular Ca2+ and intracellular pH similar to those occurring upon induction of the AR
Ebina, Y, Meinhof, CG, Schackmann, RW, Trimmer, JS, Vacquier, VD   +4 more
core  

Diversity of Listeria monocytogenes strains of clinical and food chain origins in Belgium between 1985 and 2014 [PDF]

, 2016
Listeriosis is a rare but severe disease, mainly caused by Listeria monocytogenes. This study shows the results of the laboratory-based surveillance of Listeriosis in Belgium over the period 1985-2014.
Bertrand, S, Boyen, Filip, Ceyssens, PJ, Dierick, K, Mattheus, W, Vanderpas, J, Vanhoof, R, Yde, M   +7 more
core   +5 more sources

How copy number variations shape brain developmental disorders: Unraveling the synaptic puzzle

Psychiatry and Clinical Neurosciences, EarlyView.
Neurodevelopmental disorders (NDDs), such as schizophrenia (SCZ), Attention‐deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD), learning disabilities, and intellectual disabilities (ID), are highly prevalent. One significant genetic factor associated with NDDs is copy number variations (CNVs), which are structural changes in the ...
Tianqi Wang, Kubra Trabzonlu, Emily Fullard Jones, Yasir Ahmed Syed   +3 more
wiley   +1 more source

Comparison between Acute and Long-Term Effects of Verapamil on Naloxane Induced Morphine Withdrawal in Mice

Journal of Research in Medical Sciences, 2004
Background: There is growing evidence indicating that neuronal calcium channels play an important role in the mechanism of Morphine dependence. Objective: To investigate the acute and long-term effects of Verapamil in Morphine dependent mice.
M Rabbani, A Jafarian, M Sobhanian
doaj  

Study on the performance and mechanism of verapamil degradation by zero-valent iron activated persulfate oxidation

Desalination and Water Treatment
Pharmaceuticals and personal care products (PPCPs) are a kind of refractory organic pollutants with large amount and wide range of pollution in environmental water, which can contaminate drinking water sources.
Xingya Wei, Weimin Geng, Bangjun Han, Renzheng Gu, Nana Li, Naiyun Gao   +5 more
doaj   +1 more source

Influence of Water Temperature on the MXR Activity and P-glycoprotein Expression in the Freshwater Snail, Physa acuta (Draparnaud, 1805) [PDF]

, 2017
P-glycoprotein (P-gp) mediated multixenobioticresistance (MXR) is a mechanism analogous to multidrug resistance, which has been extensivelycharacterized in mammalian tumours.
Assef, Yanina Andrea, Horak, Cristina Natalia   +1 more
core   +1 more source

Combination of low-dose quinidine and verapamil for multifocal ectopic Purkinje-related premature contractions in a patient with SCN5A mutation

, 2023
Kei Enokizono, Satoshi Nagase, Kohei Ishibashi, Koji Miyamoto, Takeshi Aiba, Kengo Kusano   +5 more
openalex   +1 more source

Frequency responses of human magnetophosphene perception thresholds during dark adaptation point to rod modulation

Experimental Physiology, EarlyView.
Abstract Magnetophosphenes are flickering lights perceived when an extremely low frequency magnetic field generates a sufficiently strong electric field in the head. Understanding how phosphenes are produced is crucial, as they form the basis for international safety standards and guidelines for both workers and the general population.
Nicolas Bouisset, Andres Carvallo, Sebastien Villard, Ilkka Laakso, Alexandre Legros   +4 more
wiley   +1 more source