Results 91 to 100 of about 78,658 (276)

Cluster headache in Greece: an observational clinical and demographic study of 302 patients. [PDF]

, 2016
BackgroundCluster headache (CH) is considered the most excruciating primary headache syndrome; although much less prevalent than migraine, it is not rare as it affects more than 1/1000 people.
Rapoport, Alan M, Vikelis, Michail
core   +1 more source

Can atogepant be a preventive treatment for cluster headache?—Insights from a case series

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Cluster headache (CH) is a disabling primary headache disorder with limited therapeutic options. Calcitonin gene‐related peptide (CGRP) is known to be involved in CH pathophysiology; however, except for galcanezumab (300 mg) in episodic CH, anti‐CGRP monoclonal antibodies did not reduce CH attacks in randomized clinical trials. Atogepant is an
Catarina Serrão, Filipa Dourado Sotero, Linda Azevedo Kauppila, Isabel Pavão Martins   +3 more
wiley   +1 more source

A comparative study of embedded and anesthetized zebrafish in vivo on myocardiac calcium oscillation and heart muscle contraction

Frontiers in Pharmacology, 2010
The zebrafish (Danio rerio) has been used as a model for studying vertebrate development in the cardiovascular system. In order to monitor heart contraction and cytosolic calcium oscillations, fish were either embedded in methylcellulose or anesthetized
Brian eMuntean, Christine Horvat, James Behler, Wissam AbouAlaiwi, Andromeda Nauli, Frederick Williams, Surya Nauli   +6 more
doaj   +1 more source

Plasmodium falciparum ligand binding to erythrocytes induce alterations in deformability essential for invasion [PDF]

, 2017
The most lethal form of malaria in humans is caused by Plasmodium falciparum. These parasites invade erythrocytes, a complex process involving multiple ligand-receptor interactions.
Cowman, Alan, Fleig, Andrea, Horgen, F. David, Malpede, Brian M, Nebl, Thomas, O\u27Neill, Joseph, Rogers, Kelly, Salinas, Nichole D, Sisquella, Xavier, Tham, Wai-Hong, Thompson, Jennifer K, Tolia, Niraj H, Whitehead, Lachlan   +12 more
core   +2 more sources

Etripamil Nasal Spray for Recurrent Paroxysmal Supraventricular Tachycardia Conversion: Results From the NODE‐303 Open‐Label Study

Journal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Introduction Etripamil is a fast‐acting intranasally self‐administered calcium‐channel blocker developed for termination of paroxysmal supraventricular tachycardia (PSVT). Prior studies have demonstrated safety and efficacy of etripamil for PSVT termination following an initial medically supervised test dose during sinus rhythm. NODE‐303 is an
James E. Ip, Benoit Coutu, John H. Ip, Peter A. Noseworthy, Maria L. Parody, Farhad Rafii, Samuel F. Sears, Narendra Singh, Bruce S. Stambler, Naeem K. Tahirkheli, Juan Agudelo‐Uribe, Derek Hu, Silvia Shardonofsky, Muhammad B. Sheikh, Anita Holz, David B. Bharucha, A. John Camm   +16 more
wiley   +1 more source

STAT3 and Nrf2 pathways modulate the protective effect of verapamil on lung injury of diabetic rats

Endocrine Regulations, 2018
Objective. We aimed to assess the protective role of verapamil, L-type calcium channel blockers, against early lung damage in diabetic rats. Lung injury has recently been recognized as a consequent complication of diabetes mellitus. Hyperglycemia induces
Mohamed Mervat Z., Hafez Heba M., Mohamed Hanaa H., Zenhom Nagwa M.   +3 more
doaj   +1 more source

Diversity of Listeria monocytogenes strains of clinical and food chain origins in Belgium between 1985 and 2014 [PDF]

, 2016
Listeriosis is a rare but severe disease, mainly caused by Listeria monocytogenes. This study shows the results of the laboratory-based surveillance of Listeriosis in Belgium over the period 1985-2014.
Bertrand, S, Boyen, Filip, Ceyssens, PJ, Dierick, K, Mattheus, W, Vanderpas, J, Vanhoof, R, Yde, M   +7 more
core   +5 more sources

Prognostic Impact of Spontaneous Conversion to Sinus Rhythm in Patients With Symptomatic Paroxysmal Atrial Fibrillation: A Propensity‐Matched Follow‐Up Study

Journal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Background Paroxysmal atrial fibrillation (PAF) patients do not invariably progress to persistent AF, with a consistent group of patients showing AF regression during follow‐up. The prognostic implications of spontaneous conversion (SCV) to sinus rhythm (SR) in those patients has never been evaluated yet.
Marco Valerio Mariani, Tommaso Recchioni, Nicola Pierucci, Sara Trivigno, Pietro Cipollone, Raffaele Maria Bruti, Domenico Laviola, Marta Palombi, Andrea Matteucci, Agostino Piro, Cristina Chimenti, Gioacchino Galardo, Francesco Pugliese, Carmine Dario Vizza, Carlo Lavalle   +14 more
wiley   +1 more source

Pharmacokinetics of Ilunocitinib, a New Janus Kinase Inhibitor, in Dogs

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Ilunocitinib, a novel Janus kinase inhibitor, is indicated for managing pruritus and skin lesions associated with canine allergic and atopic dermatitis. Pharmacokinetics of ilunocitinib were investigated following single intravenous and oral administrations, both in fed and fasted states.
Kirsten Boerngen, Yogini Patel, Melissa Pittorino, Céline E. Toutain   +3 more
wiley   +1 more source

Effects of verapamil combinations with enalapril or indapamide on plasma, vascular and platelet hemostasis and biochemical markers of endothelial dysfunction in patients with arterial hypertension and metabolic syndrome

Российский кардиологический журнал, 2008
The combination of verapamil retard and enalapril, or verapamil retard and indapamide SR similarly and significantly increased high-density lipoprotein cholesterol and stable NO2 metabolite levels, reducing platelet aggregation in patients with metabolic
N. M. Krasnova, T. P. Kalashnikova, A. I. Vengerovsky, E. M. Idrisova, I. V. Kulagina, T. E. Suslova, O. V. Gruzdeva, S. V. Kremeno, N. M. Zheltonogova, A. A. Shishkina, R. S. Karpov   +10 more
doaj