Results 111 to 120 of about 80,362 (282)

Strategy for Identifying Rational Sensitivity Analysis Using PBPK Modeling for Precipitant Drug–Drug Interaction Predictions

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 2, Page 314-317, February 2026.
Physiology Based Pharmacokinetic (PBPK) modeling is an established essential tool for predicting and/or analyzing drug–drug interactions (DDI). Uncertainty and variability associated with in vitro determined DDI‐related parameters have often been considered a limitation for predicting PBPK‐DDIs.
Kunal S. Taskar   +2 more
wiley   +1 more source

EMERGENCY TREATMENT OF SVT: ADENOSINE VERSUS VERAPAMIL

open access: yesJournal of University Medical & Dental College, 2017
: Introduction: Supraventricular tachycardia (SVT) is a common arrhythmia seen in critical care settings. After vagal maneuvers, adenosine 6 to 12 mg intravenous bolus is the initial drug of choice.
Naeem Asghar   +2 more
doaj  

Suppression of Gelatinase Activity in Human Peripheral Blood Mononuclear Cells by Verapamil [PDF]

open access: yesCell Journal, 2014
Objective: Gelatinases are a large group of proteolytic enzymes that belong to the matrix metalloproteinases (MMPs). MMPs are a broad family of peptidases, which proteolyse the extracellular matrix and have an important role in inflammation. Verapamil is
Fatemeh Hajighasemi, Neda Kakadezfuli
doaj  

A comparative study of embedded and anesthetized zebrafish in vivo on myocardiac calcium oscillation and heart muscle contraction

open access: yesFrontiers in Pharmacology, 2010
The zebrafish (Danio rerio) has been used as a model for studying vertebrate development in the cardiovascular system. In order to monitor heart contraction and cytosolic calcium oscillations, fish were either embedded in methylcellulose or anesthetized
Brian eMuntean   +6 more
doaj   +1 more source

Rate-Control or Rhythm-Contol: Where do we stand? [PDF]

open access: yes, 2005
Atrial fibrillation is the most common sustained rhythm disturbance and its prevalence is increasing worldwide due to the progressive aging of the population.
A, Dello Russo   +6 more
core   +1 more source

Cluster headache in Greece: an observational clinical and demographic study of 302 patients. [PDF]

open access: yes, 2016
BackgroundCluster headache (CH) is considered the most excruciating primary headache syndrome; although much less prevalent than migraine, it is not rare as it affects more than 1/1000 people.
Rapoport, Alan M, Vikelis, Michail
core   +1 more source

Duplicate Prescription Patterns in Patients With Substance Use Disorders

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 1, February 2026.
ABSTRACT This study sought to investigate the frequency and characteristics of duplicate prescriptions (DPs) in psychiatric inpatients with substance use disorders using a DP classification that differentiates between appropriate DPs (ADPs) and potentially inappropriate DPs (PIDPs). The study was conducted as a monocentric retrospective cross‐sectional
Johannes Heck   +8 more
wiley   +1 more source

Sodium glucose co‐transporter 2 inhibitors versus dipeptidyl peptidase‐4 inhibitors and the risk of ventricular arrhythmia among patients with type 2 diabetes: A population‐based cohort study

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 935-945, February 2026.
Abstract Aims To determine whether sodium glucose co‐transporter 2 inhibitors (SGLT2i) use, compared with dipeptidyl peptidase‐4 inhibitors (DPP4i) use, is associated with the risk of ventricular arrhythmias (VA) among patients with type 2 diabetes. Materials and Methods We conducted a population‐based cohort study using a prevalent new‐user design and
Wang‐Choi Tang   +5 more
wiley   +1 more source

Preincisional and Postincisional Epidural Bupivacaine, Ketamin and Verapamil Effects on Postoperative Analgesic Consumption in Knee Replacement Surgery

open access: yesAnkara Üniversitesi Tıp Fakültesi Mecmuası, 2011
Patients and method: 164 patients undergoing total knee arthroplasty were randomly divided into 8 groups. The study groups are, group 1 (preB), preincisional bupivacaine, postincisional saline; group 2 (postB), preincisional saline, postincisional ...
Enver Özgencil   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy