Results 111 to 120 of about 78,658 (276)

The cardiac work-loop technique:An in vitro model for identifying and profiling drug-induced changes in inotropy using rat papillary muscles [PDF]

open access: yes, 2020
AJ Taberner   +56 more
core   +1 more source

Idiopathic Fascicular Ventricular Tachycardia [PDF]

open access: yes, 2004
Idiopathic fascicular ventricular tachycardia is an important cardiac arrhythmia with specific electrocardiographic features and therapeutic options. It is characterized by relatively narrow QRS complex and right bundle branch block pattern. The QRS axis
Francis, Johnson   +4 more
core   +2 more sources

Mechanisms of Pilocarpine‐Induced Nitric Oxide and Prostaglandin Production in Porcine Ciliary Muscle

open access: yesFASEB BioAdvances, Volume 7, Issue 11, November 2025.
Pilocarpine activates M1 and M3 muscarinic receptors in porcine ciliary muscle, engaging calcium‐dependent phospholipase C (PLC), nitric oxide synthase (NOS), and cyclooxygenase (COX) pathways that increase prostaglandin E2 (PGE2) synthesis. Beyond nitric oxide (NO) modulation, PGE2 emerges as a key mediator linking muscarinic signaling to ciliary ...
Giovanna Benozzi   +3 more
wiley   +1 more source

Characterization of a monoclonal antibody that induces the acrosome reaction of sea urchin sperm. [PDF]

open access: yes, 1987
A monoclonal antibody, J18/29, induces the acrosome reaction (AR) in spermatozoa of the sea urchin Strongylocentrotus purpuratus. J18/29 induces increases in both intracellular Ca2+ and intracellular pH similar to those occurring upon induction of the AR
Ebina, Y   +4 more
core  

Novel 5-oxo-hexahydroquinoline derivatives: design, synthesis, in vitro P-glycoprotein-mediated multidrug resistance reversal profile and molecular dynamics simulation study [PDF]

open access: yes, 2017
Overexpression of the efflux pump P-glycoprotein (P-gp) is one of the important mechanisms of multidrug resistance (MDR) in many tumor cells. In this study, 26 novel 5-oxo-hexahydroquinoline derivatives containing different nitrophenyl moieties at C-4 ...
Edraki, N.   +7 more
core   +1 more source

Peyronie's disease in the United States: A real‐world, 13‐year nationwide analysis of demographics, clinical characteristics, and treatment trends

open access: yesAndrology, Volume 13, Issue 8, Page 2265-2272, November 2025.
Abstract Background Real‐world data on Peyronie's disease remains limited. Objectives Describe the demographics, clinical characteristics, and therapeutic management of Peyronie's disease patients in the United States. Materials and methods A retrospective analysis was conducted using the PearlDiver Mariner database (2010–2022).
Angelo Orsini   +15 more
wiley   +1 more source

EMERGENCY TREATMENT OF SVT: ADENOSINE VERSUS VERAPAMIL

open access: yesJournal of University Medical & Dental College, 2017
: Introduction: Supraventricular tachycardia (SVT) is a common arrhythmia seen in critical care settings. After vagal maneuvers, adenosine 6 to 12 mg intravenous bolus is the initial drug of choice.
Naeem Asghar   +2 more
doaj  

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