Results 21 to 30 of about 80,362 (282)

Genetic variants related to successful migraine prophylaxis with verapamil

open access: yesMolecular Genetics & Genomic Medicine, 2021
Background Currently, there is no biologically based rationale for drug selection in migraine prophylactic treatment. Methods To investigate the genetic variation underlying treatment response to verapamil prophylaxis, we selected 225 patients from a ...
Fred Michael Cutrer   +10 more
doaj   +1 more source

The protective effect of bee venom against verapamil embryotoxicity during prenatal liver and kidney development of mice Mus musculus

open access: yesJournal of Basic and Applied Zoology, 2016
Verapamil is a calcium channel blocker that has been widely used in the treatment of cardiovascular abnormalities, hypertension and angina pectoris. The present study investigates the effect of bee venom against verapamil embryotoxicity, bee venom (BV ...
Amin A. Seleem
doaj   +1 more source

Administration of Vitamin D Metabolites Affects RNA Expression of Xenobiotic Metabolising Enzymes and Function of ABC Transporters in Rats [PDF]

open access: yes, 2019
From studies on different species and in cell culture systems, it has been suggested that vitamin D metabolites might affect themetabolism and elimination of xenobiotics.
Hansen, Kathrin   +7 more
core   +1 more source

Comparative Effects of Verapamil, Nicardipine, and Nitroglycerin on Myocardial Ischemia/Reperfusion Injury

open access: yesAnesthesiology Research and Practice, 2011
The aim of this experiment was to establish whether verapamil, nicardipine, and nitroglycerin have (1) infarct size-limiting effects and (2) antiarrhythmic effects in in vivo rabbit hearts during ischemia/reperfusion.
Hitoshi Yui   +6 more
doaj   +1 more source

Cluster headache management and beyond [PDF]

open access: yes, 2015
The therapeutic management of cluster headache is based on a very stable triad of drugs. Acute treatment has, in subcutaneous sumatriptan, its gold standard if compared to pure oxygen or indomethacin.
Martelletti, Paolo
core   +1 more source

Efficacy of Multi-Modal Migraine Prophylaxis Therapy on Hyperacusis Patients. [PDF]

open access: yes, 2020
ObjectivesTo evaluate the efficacy of a multi-modal migraine prophylaxis therapy for patients with hyperacusis.MethodsIn a prospective cohort, patients with hyperacusis were treated with a multi-modal step-wise migraine prophylactic regimen ...
Abouzari, Mehdi   +7 more
core  

The Trypanosoma cruzi enzyme TcGPXI is a glycosomal peroxidase and can be linked to trypanothione reduction by glutathione or tryparedoxin. [PDF]

open access: yes, 2002
Trypanosoma cruzi glutathione-dependent peroxidase I (TcGPXI) can reduce fatty acid, phospholipid, and short chain organic hydroperoxides utilizing a novel redox cycle in which enzyme activity is linked to the reduction of trypanothione, a parasite ...
Bromley, Elizabeth V   +5 more
core   +4 more sources

Verapamil Alleviates Myocardial Ischemia/Reperfusion Injury by Attenuating Oxidative Stress via Activation of SIRT1

open access: yesFrontiers in Pharmacology, 2022
Myocardial ischemia/reperfusion (I/R) injury is a potential complication of ischemic heart disease after recanalization. One of the primary reasons for I/R injury is the excessive accumulation of reactive oxygen species (ROS) in cardiomyocytes. Verapamil,
Mi Bao   +15 more
doaj   +1 more source

Identification of side population cells in mouse primordial germ cells and prenatal testis [PDF]

open access: yes, 2011
In mammals, the stem cells of spermatogenesis are derived from an embryonic cell population called primordial germ cells (PGCs). Spermatogonial stem cells displaying the "side population" (SP) phenotype have been identified in the immature and adult ...
De Felici, Massimo   +6 more
core   +2 more sources

Verapamil Blocks Scopolamine Enhancement Effect on Memory Consolidation in Passive Avoidance Task in Rats

open access: yesFrontiers in Pharmacology, 2017
Our recent data have indicated that scopolamine, a non-selective muscarinic receptor antagonist, improves memory consolidation, in a passive avoidance task, tested in rats.
Verónica Giménez De Béjar   +7 more
doaj   +1 more source

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