Colloidal Polyelectrolyte Complexes from Hyaluronic Acid: Preparation and Biomedical Applications
Hyaluronic acid (HA) is a very promising polysaccharide for biomedical applications. This review provides a comprehensive overview of the development of nanoparticulate systems by HA‐based polyelectrolyte complexation. The main achievements and applications for the delivery of active substances or the construction of multifunctional platforms are ...
Huu Van Le, Didier Le Cerf
wiley +1 more source
Comprehensive translational assessment of human-induced pluripotent stem cell derived cardiomyocytes for evaluating drug-induced arrhythmias [PDF]
Induced pluripotent stem cell-derived cardiomyocytes (iPSC-CM) hold promise for assessment of drug-induced arrhythmias and are being considered for use under the comprehensive in vitro proarrhythmia assay (CiPA).
Blinova, Ksenia+17 more
core +1 more source
Comparison of Fractional CO2 Laser, Verapamil, and Triamcinolone for the Treatment of Keloid.
Objective: Scar biology is a territory less understood. The search for ideal treatment of keloid continues. The aim of this study was to compare the role of CO2 laser, triamcinolone (TAC), and verapamil in the treatment of keloid.
S. Srivastava+2 more
semanticscholar +1 more source
Light sheet microscopy with acoustic sample confinement [PDF]
Contactless sample confinement would enable a whole host of new studies in developmental biology and neuroscience, in particular, when combined with long-term, wide-field optical imaging.
Cochran, Sandy+9 more
core +7 more sources
This study used a rat model to investigate the protective effect of tadalafil and verapamil on testicular function and oxidative stress after torsion/detorsion.
M. Ameli+3 more
semanticscholar +1 more source
Models of the cardiac L‐type calcium current: A quantitative review
We discuss 73 published models of mammalian ICaL and find differences in gating kinetics, electrochemical driving force, and sensitivity to internal calcium concentrations, leading to considerable variability in their predictions. Abstract The L‐type calcium current (ICaL) plays a critical role in cardiac electrophysiology, and models of ICaL are vital
Aditi Agrawal+7 more
wiley +1 more source
Reasoning by analogy in the generation of domain acceptable ontology refinements [PDF]
Refinements generated for a knowledge base often involve the learning of new knowledge to be added to or replace existing parts of a knowledge base. However, the justifiability of the refinement in the context of the domain (domain acceptability) is ...
L. Moss+5 more
core +1 more source
Verapamil in arrhythmia. [PDF]
The antiarrhythmic effects of verapamil were observed before it was appreciated that it was a calcium ion‐antagonist. Intravenous verapamil is highly effective in the termination of paroxysmal reciprocating atrioventricular tachycardia, whether associated with preexcitation or involving the atrioventricular node alone.
openaire +3 more sources
Peyronie's disease development and management in diabetic men
Abstract Background Peyronie's disease (PD) is a fibrosing disorder of the penis resulting in plaque formation and penile deformity that negatively affect sexual and psychosocial function of patients. A multifactorial etiology of PD is assumed with diabetes mellitus (DM) being a potential risk factor.
Simone Gianazza+11 more
wiley +1 more source
A study of the role of nitric oxide in the mechanism of action of hydroalcoholic extract of saffron (Crocus sativus) on the electrophysiological properties of the rabbit atrioventricular node [PDF]
Biologically active substances of plant origin represent an essential branch of modern cardiovascular pharmacotherapy. Furthermore, drugs of plant origin have the advantage of weaker adverse effects and lower prices than synthetic drugs.
Khori, V.+3 more
core +1 more source