Results 61 to 70 of about 101,449 (340)
Acta Dermato-Venereologica, 2016 A double-blind randomized controlled trial with a paired split-scar design compared verapamil, an L-type Ca2+ channel antagonist, and triamcinolone for prevention of keloid recurrence after excision.
P. Danielsen +10 more
semanticscholar +1 more source
Direct Monitoring of Verapamil Level in Exhaled Breath Condensate Samples [PDF]
Pharmaceutical Sciences, 2019 Background: In this research, an enhanced fluorimetric assay was developed for the direct monitoring of verapamil in exhaled breath condensate (EBC). The method is based on a binding–induced rigidity inside the sodium dodecyl sulfate (SDS) micelle which ...
Fariba Pourkarim +4 more
doaj +1 more source
Nimodipine-refractory reversible cerebral vasoconstriction syndrome treated effectively with verapamil [PDF]
Precision and Future Medicine, 2020 Reversible cerebral vasoconstriction syndrome (RCVS) is characterized by recurrent thunderclap headache and reversible multifocal vasoconstrictions of the cerebral arteries. There are no treatment guidelines despite its potential for precarious outcomes.
So Young Park +4 more
doaj +1 more source
, 2011 In this work we monitor the catalytic mechanism of P-glycoprotein (Pgp) using single-molecule fluorescence resonance energy transfer (FRET). Pgp, a member of the ATP binding cassette family of transport proteins, is found in the plasma membrane of animal
Boersch, Michael +4 more
core +1 more source
Journal of Cerebral Blood Flow and Metabolism, 2016 While clinical trials have now solidified the role of thrombectomy in emergent large vessel occlusive stroke, additional therapies are needed to optimize patient outcome.
Michael E. Maniskas +4 more
semanticscholar +1 more source
Novel 5-oxo-hexahydroquinoline derivatives: design, synthesis, in vitro P-glycoprotein-mediated multidrug resistance reversal profile and molecular dynamics simulation study [PDF]
, 2017 Overexpression of the efflux pump P-glycoprotein (P-gp) is one of the important mechanisms of multidrug resistance (MDR) in many tumor cells. In this study, 26 novel 5-oxo-hexahydroquinoline derivatives containing different nitrophenyl moieties at C-4 ...
Edraki, N. +7 more
core +1 more source
Methylglyoxal induces cardiac dysfunction through mechanisms involving altered intracellular calcium handling in the rat heart [PDF]
Chemico-Biological Interactions, 2024, 394, pp.110949Methylglyoxal (MGO) is an endogenous, highly reactive dicarbonyl metabolite generated under hyperglycaemic conditions. MGO plays a role in developing pathophysiological conditions, including diabetic cardiomyopathy. However, the mechanisms involved and the molecular targets of MGO in the heart have not been elucidated.
arxiv +1 more source
BMB Reports, 2017 Nuclear factor erythroid 2-related factor 2 (Nrf2) provides a cellular defense against oxidative stress by inducing the expression of antioxidant and detoxification enzymes.
D. Lee +5 more
semanticscholar +1 more source
Advanced Science, EarlyView.The therapeutic potential of ApoVs derived from stem cells from human exfoliated deciduous teeth (SHED‐ApoVs) in the treatment of CD8+ T cell‐mediated hypersensitivity reactions is noteworthy. SHED‐ApoVs are capable of fusing with the plasma membrane of CD8+ T cells, which subsequently triggers a series of events characterized by calcium overload ...
Anqi Liu +13 more
wiley +1 more source
Idiopathic Fascicular Ventricular Tachycardia [PDF]
, 2004 Idiopathic fascicular ventricular tachycardia is an important cardiac arrhythmia with specific electrocardiographic features and therapeutic options. It is characterized by relatively narrow QRS complex and right bundle branch block pattern. The QRS axis
Francis, Johnson +4 more
core +2 more sources