Results 111 to 120 of about 10,151 (207)

Association of versican turnover with all-cause mortality in patients on haemodialysis.

open access: yesPLoS ONE, 2014
ObjectiveCardiovascular diseases are among the most common causes of mortality in renal failure patients undergoing haemodialysis. A high turnover rate of the proteoglycan versican, represented by the increased presence of its fragmentation products in ...
Federica Genovese   +4 more
doaj   +1 more source

Roles of versican in cancer biology - tumorigenesis, progression and metastasis [PDF]

open access: yes, 2013
Versican, a large extracellular matrix proteoglycan accumulates in tumor stroma and plays a key role in both malignant transformation and tumor progression. Increased versican expression has been observed in a wide range of malignant tumors, and has
Yee, Albert J.   +2 more
core  

ADAMTS5 Orchestrates Cell Lineage Specific Patterning and Extracellular Matrix Organization During Semilunar Valve Development

open access: yesJournal of Cardiovascular Development and Disease
Aortic valve (AV) disease affects about 5% of the aging population, with AV replacement as the only treatment option. Histopathology indicates that accumulation of extracellular matrix (ECM) proteoglycans correlates with dysfunctional AVs.
Loren E. Dupuis   +4 more
doaj   +1 more source

Versican V0/V1 Is Essential For The Proliferation Of Mdpcs

open access: yesInternational Dental Journal
Aim or purpose: To evaluate the effect of Versican V0/V1 isoforms on the proliferation of mouse dental papilla cells (mDPCs). Materials and methods: Immunofluorescence staining was performed to observe the expression of GAG-β, GAG-α and EdU.
Jiayan Wu, Beizhan Jiang
doaj   +1 more source

Versican Expression during Synovial Joint Morphogenesis

open access: yes, 2011
The extracellular matrix (ECM) plays a critical role in governing cell behavior and phenotype during limb skeletogenesis. Chondroitin sulfate proteoglycans (Cspgs) are highly expressed in the ECM of precartilage mesenchymal condensations and are ...
Capehart, Anthony A.   +5 more
core  

Versican in the wound healing matrix : cellular interactions and degradation by matrix metalloproteinases

open access: yes, 2009
In wound healing, versican is a component of the provisional matrix laid down at the site of injury by proliferating myofibroblasts. Versican interacts with a variety of matrix molecules and is believed to interact with the cell surface.
Pourmalek, Saloumeh
core   +1 more source

Studies on regulation of versican gene expression by hypoxia in primary human macrophages

open access: yes, 2011
Hypoxia is a hallmark of many pathological tissues. Macrophages accumulate in hypoxic sites and up-regulate a number of hypoxia-inducible genes. The extracellular matrix glycoprotein versican has recently been identified as one such gene, but the ...
Fattah Sotoodehnejadnematalahi (752003)
core   +2 more sources

Influencia de componentes de la matriz extracelular en la agresividad y potencial invasor del cáncer cérvicouterino: ¿Qué hay de nuevo?

open access: yesRevista Chilena de Obstetricia y Ginecología, 2011
El cáncer cérvico uterino (CCU) es una patología de alta incidencia y mortalidad. La investigación hasta ahora se ha enfocado en estudiar su asociación con virus papiloma.
Paula Segura H, Leonor Moyano S
doaj  

Versican Expression During Embryonic Development in the Mouse

open access: yes, 2014
Thesis (Master's)--University of Washington, 2014Versican is a chondroitin sulfate proteoglycan and a component of the extracellular matrix that has previously been shown to have an important role during the embryonic development of many organs. In this
Snyder, Jessica M.
core  

ISGF3 regulates versican expression in macrophages

open access: yes
Supplemental Figure 1Growing evidence supports a role for versican as an important component of the inflammatory response, with both pro- and anti-inflammatory roles depending on the specific context of the system or disease under investigation. Our goal
Brune, Jourdan   +6 more
core  

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