Results 101 to 110 of about 15,922 (221)

Pushing Frontiers for Proteoglycans

Proteoglycan Research, Volume 4, Issue 2, April 2026.
ABSTRACT Almost half of proteins have one or more post‐translational glycosylation modifications involving the addition of glycan structures. Proteoglycans are a class of glycosylated proteins with one or more glycosaminoglycan (GAG) chains covalently attached to the core protein.
Marissa L. Maciej‐Hulme
wiley   +1 more source

Targeting the tumor microenvironment in colorectal peritoneal metastases

, 2020
Peritoneal metastasis (PM) occurs in approximately one in four colorectal cancer (CRC) patients. The pathophysiology of colorectal PM remains poorly characterized. Also, the efficacy of current treatment modalities, including surgery and intraperitoneal (
Ceelen, Wim, De Wever, Olivier, Heriot, Alexander G., Narasimhan, Vignesh, Ramsay, Robert G.   +4 more
core   +1 more source

Associations of Adipocyte-derived Versican and Macrophage-derived Biglycan with Body Adipose Tissue and Hepatosteatosis in Obese Children

JCRPE
INTRODUCTION: In animal models of obesity, adipocyte-derived versican, and macrophage-derived biglycan play a crucial role in mediating adipose tissue inflammation.
Reyhan Deveci Sevim, Mustafa Gök, Özge Çevik, Ömer Erdoğan, Sebla Güneş, Tolga Ünüvar, Ahmet Anık   +6 more
doaj   +1 more source

Pentosan polysulfate decreases myocardial expression of the extracellular matrix enzyme ADAMTS4 and improves cardiac function in vivo in rats subjected to pressure overload by aortic banding.

PLoS ONE, 2014
BackgroundWe hypothesized that cleavage of the extracellular matrix (ECM) proteoglycans versican and aggrecan by ADAMTS (a disintegrin and metalloprotease with thrombospondin motifs) proteases, which contributes to stress-induced ECM-reorganization in ...
Maria Vistnes, Jan Magnus Aronsen, Ida G Lunde, Ivar Sjaastad, Cathrine R Carlson, Geir Christensen   +5 more
doaj   +1 more source

Profound Re-Organization of Cell Surface Proteome in Equine Retinal Pigment Epithelial Cells in Response to In Vitro Culturing [PDF]

, 2012
The purpose of this study was to characterize the cell surface proteome of native compared to cultured equine retinal pigment epithelium (RPE) cells. The RPE plays an essential role in visual function and represents the outer blood-retinal barrier.
Aisenbrey, Alcazar, Alge, Bhutto, Bodaghi, Burke, Campochiaro, Christoph Szober, Chu, Claudia Alge-Priglinger, Clegg, Cornelia Deeg, Deeg, Deeg, Deeg, Deeg, Deeg, Degroote, Doherty, Dunn, Eberhardt, Ehrenhofer, Greer, Gullapalli, Gundersen, Ham, Hamel, Hauck, Hauck, Hauck, Hauck, Ho, Huang, Karl, Kerstin Euler, Kristina Fröhlich, Li, Limb, Machemer, Marius Ueffing, McBee, Milyushina, Mochizuki, Muramatsu, Nagai, Parker, Philp, Rizzolo, Rotilio, Singer, Stefanie Hauck, Strauss, Vacanti, Wolf, Wu   +54 more
core   +3 more sources

Effects of Versican V0/V1 gene silencing on biological behaviors of mouse dental papilla cells [PDF]

Kouqiang yixue
Objective To investigate the effect of Versican V0/V1 on biological behaviors of mouse dental papilla cells (mDPCs). Methods mDPCs were isolated from C57BL/6J mice at embryonic day 16.5 (E16.5).
WU Jiayan, HUANG Haiyan, SONG Chenyu, JIANG Beizhan
doaj   +1 more source

Age-related differences in human skin proteoglycans [PDF]

, 2017
Previous work has shown that versican, decorin and a catabolic fragment of decorin, termed decorunt, are the most abundant proteoglycans in human skin. Further analysis of versican indicates that four major core protein species are present in human skin ...
Calabro, Anthony, Caplan, Arnold I., Carrino, David A., Darr, Aniq B., Dours-Zimmermann, Maria T., Hascall, Vincent C., Sandy, John D., Sorrell, J Michael, Zimmermann, Dieter R.   +8 more
core  

Expression of biomarkers modulating prostate cancer angiogenesis: Differential expression of annexin II in prostate carcinomas from India and USA [PDF]

, 2003
Background Prostate cancer (PCa) incidences vary with genetic, geographical and ethnic dietary background of patients while angiogenesis is modulated through exquisite interplay of tumor-stromal interactions of biological macromolecules.
Dinda Amit K, Johansson Sonny L, Gopalakrishnan Velliyur K, Yuan Yawei, Liu Jie, Banerjee Abhijit G, Gupta Narmada P, Trevino Lindsey, Vishwanatha Jamboor K   +8 more
core   +2 more sources

Consequences of loss of progesterone receptor expression in development of invasive endometrial cancer [PDF]

, 2003
PURPOSE: In endometrial cancer, loss of progesterone receptors (PR) is associated with more advanced disease. This study aimed to investigate the mechanism of action of progesterone and the loss of its receptors (PRA and PRB) in ...
Blok, L.J. (Leen), Brinkmann, A.O. (Albert), Burger, C.W. (Curt), Chadha-Ajwani, S. (Savi), Gielen, S.C.J.P. (Susanne), Grootegoed, J.A. (Anton), Hanekamp, E.E. (Eline), Huikeshoven, F.J. (Frans), Kühne, L.C. (Liesbeth), Ruiter, P.E. (Petra) de, Smid-Koopman, E. (Ellen)   +10 more
core  

The role of proteases in pathologies of the synovial joint [PDF]

, 2008
Synovial (diarthrodial) joints are employed within the body to provide skeletal mobility and have a characteristic structure adapted to provide a smooth almost frictionless surface for articulation.
Buttle, D, Jones, GC, Riley, GP
core   +1 more source