Results 101 to 110 of about 10,151 (207)
Association of Versican with Dermal Matrices and its Potential Role in Hair Follicle Development and Cycling [PDF]
, 1995 Versican is a member of the group of aggregating proteoglycans involved in matrix assembly and structure and in cell adhesion. We examined changes in the distribution of versican in mammalian skin, with emphasis on hair follicle development and cycling ...
LeBaron, Richard G. +5 more
core +1 more source
Immunoregulatory roles of versican proteolysis in the myeloma microenvironment
Blood, 2016 Key Points Interplay between myeloma niche stromal cells and myeloid cells generates versikine, a novel damage-associated molecular pattern. Versikine may promote antigen-presenting cell maturation and CD8+ T-cell activation/recruitment to the tumor bed.
Chelsea, Hope +12 more
openaire +3 more sources
International Journal of COPD, 2017 Lian Wu,1,2 Jing Zhang,3 Jie Ming Qu,4 Chun-xue Bai,3 Mervyn J Merrilees5 1Department of Community and Health Services, Unitec, 2Department of Pharmacology & Clinical Pharmacology, University of Auckland, Auckland, New Zealand; 3Department of ...
Wu L +4 more
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PLoS ONE, 2014 BackgroundWe hypothesized that cleavage of the extracellular matrix (ECM) proteoglycans versican and aggrecan by ADAMTS (a disintegrin and metalloprotease with thrombospondin motifs) proteases, which contributes to stress-induced ECM-reorganization in ...
Maria Vistnes +5 more
doaj +1 more source
Versican increases TGF-β signaling in cultured fibroblasts.
, 2015 (A) Confocal imaging of contracted gels demonstrated the versican-transfected fibroblasts to have increased expression and incorporation of smooth muscle α-actin into their stress fibres (arrows, yellow in overlay).
Bruce M. McManus (351410) +6 more
core +1 more source
Versican increases fibroblast-mediated contraction of a collagen lattice.
, 2015 (A) Representative images of contracted collagen gels are shown along with the quantified surface areas of contracted gels. Versican significantly increased the fibroblast-mediated contraction of collagen gels (14.9 ± 0.7% vs 24.8 ± 1.8% of initial gel ...
Bruce M. McManus (351410) +6 more
core +1 more source
Interleukin-11 Promotes the Progress of Gastric Carcinoma via Abnormally Expressed Versican
International Journal of Biological Sciences, 2012 Versican, a ubiquitous component of the extracellular matrix (ECM), accumulates both in tumor stroma and cancer cells and is highly regulated by various cytokines.
Zhenwei Zhang, Jianpeng Zhang, Lei Miao, Ke Liu, Shengsheng Yang, Chuanyong Pan, Binghua Jiao
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Frontiers in Genetics, 2019 Only a few genes involved in teeth development and morphology are known to be responsible for tooth abnormalities in Mendelian-inherited diseases. We studied an inbred family of Pakistani origin in which two first-cousin born brothers are affected by ...
Stefania Bigoni +24 more
doaj +1 more source
Immunomodulation of Influenza A Virus Infection by Fibroblast-Derived Versican
, 2023 Thesis (Ph.D.)--University of Washington, 2023Viral and bacterial lung infections place a significant burden on public health. Versican, an extracellular matrix (ECM) chondroitin sulfate proteoglycan, is a critical coordinator of the innate immune ...
Brune, Jourdan E.
core
Versican、CTGF、TGFβ1在子宫内膜样腺癌及子宫内膜上皮内瘤变中的表达和意义
Zhongguo shiyan zhenduanxue, 2016 目的探讨多功能蛋白聚糖（Versican）、结缔组织生长因子（CTGF）、转化生长因子β1（TGFβ1）在子宫内膜样腺癌（EA）及子宫内膜上皮内瘤变（EIN）中的表达及三者相关性。方法采用免疫组织化学方法对76例EA和35例EIN中Versican、CTGF、TGFβ1的表达情况进行了分析,阐述其在EA及EIN中的表达特征及相互关系。结果在76例EA中Versican、CTGF、TGFβ1阳性表达率分别为75%,65.8%,69.7%,在35例EIN中阳性表达率分别为42.9%,37.1%,37.1 ...
汪锋 +6 more
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