Results 151 to 160 of about 8,199 (176)

Versican localizes to the nucleus in proliferating mesenchymal cells

Cardiovascular Pathology, 2015
Versican is a versatile and highly interactive chondroitin sulfate proteoglycan that is found in the extracellular matrix (ECM) of many tissues and is a major component of developing and developed lesions in atherosclerotic vascular disease. In this paper, we present data to indicate that versican may have important intracellular functions in addition ...
Jon M, Carthy, Thomas, Abraham, Anna J, Meredith, Seti, Boroomand, Bruce M, McManus   +4 more
openaire   +2 more sources

Glycosaminoglycan and versican deposits in taxane-induced sclerosis

British Journal of Dermatology, 2015
Docetaxel and paclitaxel are widely used in the treatment of various malignant neoplasms. Taxane-induced sclerosis is dose-dependent and usually not generalized. Little information on the pathogenesis of scleroderma is currently available. Here, we report a case of generalized scleroderma and a case of early-stage oedematous sclerosis, both of which ...
K. Okada, Y. Endo, Y. Miyachi, Y. Koike, Y. Kuwatsuka, A. Utani   +5 more
openaire   +2 more sources

Hyaluronan, CD44 and versican in epidermal keratinocyte tumours

British Journal of Dermatology, 2003
The high molecular weight polysaccharide hyaluronan is a major component of the extracellular matrix between the vital cells of human skin epidermis. The levels of hyaluronan, and those of the hyaluronan receptor CD44 and the hyaluronan binding proteoglycan versican, correlate with the aggressiveness of different human carcinomas of epithelial origin ...
S, Karvinen, V-M, Kosma, M I, Tammi, R, Tammi   +3 more
openaire   +2 more sources

Versican: Role in Cancer Tumorigenesis

2017
Versican is an extracellular matrix proteoglycan that is expressed in a wide variety of cancers. Several cellular sources for versican have been identified in a multitude of cancers including tumor cells, stromal cells, myeloid cells, and lymphoid cells.
Paul A. Keire, Inkyung Kang, Thomas N. Wight   +2 more
openaire   +1 more source

Versican Promotes Cardiomyocyte Proliferation and Cardiac Repair

Circulation
BACKGROUND: The adult mammalian heart is incapable of regeneration, whereas a transient regenerative capacity is maintained in the neonatal heart, primarily through the proliferation of preexisting cardiomyocytes. Neonatal heart regeneration after myocardial injury is accompanied by an expansion of cardiac fibroblasts and ...
Jie Feng, Yandong Li, Yan Li, Qianqian Yin, Haotong Li, Jun Li, Bin Zhou, Jian Meng, Hong Lian, Mengge Wu, Yahuan Li, Kefei Dou, Weihua Song, Bin Lu, Lihui Liu, Shengshou Hu, Yu Nie   +16 more
openaire   +2 more sources

Versican

1998
Shirley Ayad, Ray Boot-Handford, Martin J. Humphries, Karl E. Kadler, Adrian Shuttleworth   +4 more
openaire   +2 more sources

Prognostic significance of stromal versican expression in human endometrial cancer

Annals of Oncology, 2007
J Kodama, A Hongo, Yuji Hiramatsu
exaly  

The biological role and regulation of versican levels in cancer

Cancer and Metastasis Reviews, 2009
Carmela Ricciardelli, Miranda P Ween, Darryl L Russell   +2 more
exaly  

Inhibition of Versican Synthesis by Antisense Alters Smooth Muscle Cell Phenotype and Induces Elastic Fiber Formation In Vitro and in Neointima After Vessel Injury

Circulation Research, 2006
Mervyn J Merrilees, Alexander W Clowes, Aleksander Hinek   +2 more
exaly  

Versican: a versatile extracellular matrix proteoglycan in cell biology

Current Opinion in Cell Biology, 2002
Thomas N Wight
exaly