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Perspectives on developmental neurobiology, 1997
Proteoglycans have long been recognized as participating in a number of biological activities ranging from structural roles to regulation of transcription. Versican is a large chondroitin sulfate proteoglycan expressed in several tissues, including the nervous system.
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Proteoglycans have long been recognized as participating in a number of biological activities ranging from structural roles to regulation of transcription. Versican is a large chondroitin sulfate proteoglycan expressed in several tissues, including the nervous system.
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T-cell responses to versican in ankylosing spondylitis
Rheumatology International, 2009The objective of our study was to undertake a systematic analysis of the T-cell response to the proteoglycan versican G1-globular domain (VG1) in ankylosing spondylitis (AS) as immunity to VG1 in mice can induce a pathology closely resembling AS. Peripheral blood lymphocytes from 36 AS patients and 33 healthy controls were incubated with recombinant ...
Tae-Jong, Kim +5 more
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Versican modulates gap junction intercellular communication
Journal of Cellular Physiology, 2007AbstractVersican is a large chondroitin sulfate proteoglycan and belongs to the family of lecticans. Versican possesses two globular domains, G1 and G3 domain, separated by a CS‐attachment region. The CS‐attachment region present in the middle region is divided into two spliced domains named CSα and β.
Wang, Sheng +4 more
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Versican: Role in Cancer Tumorigenesis
2017Versican is an extracellular matrix proteoglycan that is expressed in a wide variety of cancers. Several cellular sources for versican have been identified in a multitude of cancers including tumor cells, stromal cells, myeloid cells, and lymphoid cells.
Paul A. Keire +2 more
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Versican Promotes Cardiomyocyte Proliferation and Cardiac Repair
CirculationBACKGROUND: The adult mammalian heart is incapable of regeneration, whereas a transient regenerative capacity is maintained in the neonatal heart, primarily through the proliferation of preexisting cardiomyocytes. Neonatal heart regeneration after myocardial injury is accompanied by an expansion of cardiac fibroblasts and ...
Jie Feng +16 more
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Aggrecan and versican: two brothers close or apart
American Journal of Physiology - Cell Physiology, 2022Hideto Watanabe
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Defining the versican interactome in lung health and disease
American Journal of Physiology - Cell Physiology, 2022Jourdan E Brune +2 more
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Prognostic significance of stromal versican expression in human endometrial cancer
Annals of Oncology, 2007J Kodama, A Hongo, Y Hiramatsu
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Versican: a versatile extracellular matrix proteoglycan in cell biology
Current Opinion in Cell Biology, 2002Thomas N Wight
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