Results 1 to 10 of about 13,176,453 (293)

Enhancing very long chain fatty acids production in Yarrowia lipolytica. [PDF]

Microb Cell Fact, 2022
Background Very long chain fatty acids (VLCFA) and their derivatives are industrially attractive compounds. The most important are behenic acid (C22:0) and erucic acid (C22:1Δ13), which are used as lubricants, and moisturizers.
Gajdoš P, Urbaníková V, Vicenová M, Čertík M.   +3 more
europepmc   +4 more sources

Very long-chain fatty acids drive 1-deoxySphingolipid toxicity. [PDF]

Nat Commun
1-Deoxysphingolipids (1-deoxySLs) are atypical sphingolipids formed when serine palmitoyltransferase incorporates L-alanine instead of L-serine. Elevated 1-deoxySLs are associated with hereditary sensory neuropathy type 1 and diabetic neuropathy, but the
Majcher A, Karsai G, Yusifov E, Schaettin M, Malagola E, Horvath P, Li J, Rodriguez-Gallardo S, Shimizu K, Zhibo G, Dubey R, Peterson T, Harayama T, Hornemann T.   +13 more
europepmc   +5 more sources

Genotoxicity evaluation of a fish oil concentrate containing Very Long Chain Fatty Acids. [PDF]

Toxicol Rep, 2023
Very long chain fatty acids (VLCFAs) are lipids found in fish with a chain length longer than C22. They represent a minor lipid fraction composing of less than 1% of the total lipid.
Tobin D, Svensen H, Stoknes I, Dornish M.   +3 more
europepmc   +2 more sources

Saturated very long-chain fatty acids regulate macrophage plasticity and invasiveness. [PDF]

J Neuroinflammation, 2022
Saturated very long-chain fatty acids (VLCFA, ≥ C22), enriched in brain myelin and innate immune cells, accumulate in X-linked adrenoleukodystrophy (X-ALD) due to inherited dysfunction of the peroxisomal VLCFA transporter ABCD1.
Zierfuss B, Buda A, Villoria-González A, Logist M, Fabjan J, Parzer P, Battin C, Vandersteene S, Dijkstra IME, Waidhofer-Söllner P, Grabmeier-Pfistershammer K, Steinberger P, Kemp S, Forss-Petter S, Berger J, Weinhofer I.   +15 more
europepmc   +2 more sources

Reassessing very long chain fatty acids elevations: Sitosterolemia as a non-peroxisomal cause. [PDF]

Mol Genet Metab Rep
Very-long-chain fatty acids (VLCFAs) are commonly used to diagnose peroxisomal disorders, but elevated levels may also result from other non-peroxisomal causes, leading to diagnostic challenges.
Yoldaş Çelik M, Köşeci B, Burgaç E, Yararbaş K.   +3 more
europepmc   +2 more sources

Practical preparation of unsaturated very-long-chain fatty acids (VLCFAs) and very-long-chain alkene pollinator attractants. [PDF]

Sci Rep
To prepare very-long-chain fatty acids and alkenes (VLCFAs and VLC alkenes) that are known pollinator attractants for sexually deceptive orchids, and biosynthetic precursors thereof, we applied a methodology allowing us to prepare monounsaturated VLCFAs ...
Bohman B, Bersch AJ, Flematti GR, Schlüter PM.   +3 more
europepmc   +2 more sources

Very long-chain fatty acids accumulate in breast cancer tissue and serum. [PDF]

Cancer Cell Int
Background Breast cancer (BC) remains one of the most common cancers with relatively high mortality and is associated with alterations in fatty acid (FA) metabolism.
Pakiet A, Ciosek M, Lange O, Duzowska K, Janczy A, Kapusta M, Razghonova Y, Ekman M, Abacajew-Chmyłko A, Kabata P, Mika A.   +10 more
europepmc   +2 more sources

Novel Cellular Functions of Very Long Chain-Fatty Acids: Insight From ELOVL4 Mutations. [PDF]

Front Cell Neurosci, 2019
Elongation of Very Long chain fatty acids-4 (ELOVL4) protein is a member of the ELOVL family of fatty acid elongases that is collectively responsible for catalyzing formation of long chain fatty acids.
Deák F, Anderson RE, Fessler JL, Sherry DM.   +3 more
europepmc   +2 more sources

Biosynthesis and Functions of Very-Long-Chain Fatty Acids in the Responses of Plants to Abiotic and Biotic Stresses. [PDF]

Cells, 2021
Batsale M, Bahammou D, Fouillen L, Mongrand S, Joubès J, Domergue F.   +5 more
europepmc   +2 more sources

Emerging insights into the function of very long chain fatty acids at cerebellar synapses. [PDF]

Neural Regen Res
Agbaga MP, Agbaga MP, Ahmad M.
europepmc   +2 more sources