Results 11 to 20 of about 13,176,453 (293)
Membrane Disruption by Very Long Chain Fatty Acids during Necroptosis. [PDF]
ACS Chem Biol, 2019 Necroptosis is a form of regulated cell death which results in loss of plasma membrane integrity, release of intracellular contents, and an associated inflammatory response. We previously found that saturated very long chain fatty acids (VLCFAs), which contain ≥20 carbons, accumulate during necroptosis.
Parisi LR +8 more
europepmc +6 more sources
Algae: Critical Sources of Very Long-Chain Polyunsaturated Fatty Acids [PDF]
Biomolecules, 2019 Polyunsaturated fatty acids (PUFAs), which are divided into n-3 and n-6 classes, are essential for good health in humans and many animals. They are metabolised to lipid mediators, such as eicosanoids, resolvins and protectins.
John L. Harwood
doaj +3 more sources
Interactions of very long-chain saturated fatty acids with serum albumin [PDF]
Journal of Lipid Research, 2002 The remarkable binding properties of serum albumin have been investigated extensively, but little is known about an important class of fatty acids, the very long-chain saturated fatty acids (VLCFA; >18 carbons). Although VLCFA are metabolized efficiently
Ji-Kyung Choi +5 more
doaj +3 more sources
Very Long-Chain Fatty Acids in Yeast [PDF]
Journal of Bacteriology, 1973 Novel fatty acids ranging from 20 to 30 carbons have been found in Saccharomyces cerevisiae . These comprise 1 to 2% of the total fatty acid fraction.
J W, Welch, A L, Burlingame
openaire +2 more sources
Omega 3: Should we indicate it in our patients?
Revista de la Sociedad Argentina de Diabetes, 2022 Lipids are identified as a fundamental component of the diet because they perform very important functions. They influence the modulation of immune functions and inflammatory processes; attributable to long-chain polyunsaturated fatty acids (long chain ...
Marta Milikowski
doaj +1 more source
Emerging roles of polyunsaturated fatty acid synthesis pathway in colorectal cancer
Animal Cells and Systems, 2023 The development of colorectal cancer typically involves the accumulated influences of genetic alterations, medical issues, lifestyle, and diet. Dietary fatty acids appear to affect the tumorigenesis and progression of colorectal cancer.
Young-Ah Moon
doaj +1 more source
The Overlooked Transformation Mechanisms of VLCFAs: Peroxisomal β-Oxidation
Agriculture, 2022 Beta-oxidation(β-oxidation) is an important metabolic process involving multiple steps by which fatty acid molecules are broken down to produce energy.
Qinyue Lu +4 more
doaj +1 more source
Peroxisomes attenuate cytotoxicity of very long-chain fatty acids
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2023 One of the major functions of peroxisomes in mammals is oxidation of very long-chain fatty acids (VLCFAs). Genetic defects in peroxisomal β-oxidation result in the accumulation of VLCFAs and lead to a variety of health problems, such as demyelination of nervous tissues.
Ali, Hanif +9 more
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Metabolism of Very Long-Chain Fatty Acids: Genes and Pathophysiology [PDF]
Biomolecules & Therapeutics, 2014 Fatty acids (FAs) are highly diverse in terms of carbon (C) chain-length and number of double bonds. FAs with C>20 are called very long-chain fatty acids (VLCFAs). VLCFAs are found not only as constituents of cellular lipids such as sphingolipids and glycerophospholipids but also as precursors of lipid mediators.
Sassa, Takayuki, Kihara, Akio
openaire +2 more sources
Placental transfer of long-chain polyunsaturated fatty acids (LC-PUFA) [PDF]
, 2007 Considerable evidence exists for marked beneficial effects of omega-3 long-chain polyunsaturated fatty acids (LC-PUFA) during pregnancy. The omega-3 LCPUFA docosahexaenoic acid (DHA) is incorporated in large amounts in fetal brain and other tissues ...
Hans Demmelmair +5 more
core +2 more sources