Results 181 to 190 of about 152,465 (288)

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

RAB5C Increases Endothelial Release of VWF by Regulating Vesicle Trafficking. [PDF]

Arterioscler Thromb Vasc Biol
Reventun P, Toledano-Sanz P, Delgado-Marin M, Viskadourou M, Foster DB, de Vries PS, Sabater-Lleal M, Alcharani N, Gonzalez-Cucharero C, Osburn WO, Morrison AC, Wolberg AS, Smith NL, Arvanitis M, Cohorts for Heart and Aging in Genomic Epidemiology Hemostasis Working Group, Lowenstein CJ.   +15 more
europepmc   +1 more source

Changes in neuropeptide large dense core vesicle trafficking dynamics contribute to adaptive responses to a systemic homeostatic challenge. [PDF]

iScience, 2023
Kirchner MK, Althammer F, Donaldson KJ, Cox DN, Stern JE.   +4 more
europepmc   +1 more source

A Correlative SICM‐OPM Platform for Surface and Volumetric Imaging in Live Cells

Advanced Science, EarlyView.
A multifunctional correlative imaging platform integrating Scanning Ion Conductance Microscopy (SICM) with Oblique Plane Microscopy (OPM) enables simultaneous surface topography, mechanical mapping, and 3D volumetric fluorescence imaging in live cells.
Wenzhi Hong, Ziwei Zhang, Ao Li, Ting Sun, Yunzhao Wu, Devkee M. Vadukul, Dylan Jones, Bing Li, Fengjie Liu, Francesco A. Aprile, Yuri Korchev, Julia Gorelik, David Klenerman, Andrew Shevchuk   +13 more
wiley   +1 more source

Hsc70 rescues the synaptic vesicle trafficking defects caused by α-synuclein dimers. [PDF]

MicroPubl Biol, 2023
Brady EB, McQuillan M, Medeiros AT, Bubacco L, Sousa R, Lafer EM, Morgan JR.   +6 more
europepmc   +1 more source

Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus

Advanced Science, EarlyView.
This study uncovers a conserved PIP2‐dependent secretory pathway of orbivirus NS3 that induces vascular leakage. Pharmacological disruption of PIP2‐NS3 interaction significantly reduces viral pathogenicity and provides protective efficacy in murine models, establishing PIP2‐mediated NS3 secretion as both a key virulence determinant and a promising ...
Junyong Guan, Dong Zhou, Ran Shao, Xing Liu, Jin Peng, Yingran Huang, Shuhui Qi, Cankun Xi, Menghang Wang, Bin Sun, Yinglin Qi, Xin Yin   +11 more
wiley   +1 more source

Ionic Mechanisms of Two-Pore Channel Regulation of Vesicle Trafficking. [PDF]

Cells
Zhang H, Zhu MX.
europepmc   +1 more source

ANXA2‐mediated Phagocytosis Generates AR+ Macrophages to Confer Enzalutamide Resistance in Prostate Cancer

Advanced Science, EarlyView.
A novel resistance mechanism is mediated through phagocytosis of cancer cells by AR+ TAMs. This process, dependent on ANXA2, enables macrophages to acquire AR protein from engulfed tumor cells. The internalized AR translocates into the macrophage nucleus, where it binds directly to the IL‐6 promoter, augmenting IL‐6 transcription and secretion ...
Yong Luo, Tianlong Luo, Lingfeng Li, Qi Sun, Dongquan Li, Shanhe Huang, Zonglin Li, Weilong Lin, Yuan Ou, Tao Du, Shengmeng Peng, Kewei Xu, Bisheng Cheng, Hai Huang   +13 more
wiley   +1 more source

Defender or accomplice? Dual roles of plant vesicle trafficking in restricting and enabling geminiviral systemic infection. [PDF]

New Phytol
Cana-Quijada P, Morales-Martínez P, Rosas-Díaz T, Pérez-Sancho J, Jiménez-Góngora T, Navarro JA, Lozano-Durán R, Castillo AG, Pallás V, Bejarano ER.   +9 more
europepmc   +1 more source

Integrated analysis based on vesicle trafficking-related genes identifying CNIH4 as a novel therapeutic target for glioma. [PDF]

Cancer Med, 2023
Fang Z, Kong F, Zeng J, Zhang Z, Wang Y, Wang Y, Duan J, Chen L, Wang J, Liu F.   +9 more
europepmc   +1 more source