Results 11 to 20 of about 10,752 (224)

TRIM69 Inhibits Vesicular Stomatitis Indiana Virus. [PDF]

J Virol, 2019
Vesicular stomatitis Indiana virus (VSIV), formerly known as vesicular stomatitis virus (VSV) Indiana (VSVIND), is a model virus that is exceptionally sensitive to the inhibitory action of interferons (IFNs).
Rihn SJ, Aziz MA, Stewart DG, Hughes J, Turnbull ML, Varela M, Sugrue E, Herd CS, Stanifer M, Sinkins SP, Palmarini M, Wilson SJ.   +11 more
europepmc   +10 more sources

Nanopore Assay Reveals Cell-Type-Dependent Gene Expression of Vesicular Stomatitis Indiana Virus and Differential Host Cell Response. [PDF]

Pathogens, 2021
Vesicular stomatitis Indiana virus (VSIV) of genus Vesiculovirus, species IndianaVesiculovirus (formerly as Vesicular stomatitis virus, VSV) causes a disease in livestock that is very similar to the foot and mouth disease, thereby an outbreak may lead to significant economic loss.
Kakuk B, Kiss AA, Torma G, Csabai Z, Prazsák I, Mizik M, Megyeri K, Tombácz D, Boldogkői Z.   +8 more
europepmc   +7 more sources

Detection of Vesicular Stomatitis Virus Indiana from Insects Collected during the 2020 Outbreak in Kansas, USA [PDF]

Pathogens, 2021
Vesicular stomatitis (VS) is a reportable viral disease which affects horses, cattle, and pigs in the Americas. Outbreaks of vesicular stomatitis virus New Jersey serotype (VSV-NJ) in the United States typically occur on a 5–10-year cycle, usually affecting western and southwestern states.
Bethany L. McGregor, Paula Rozo-Lopez, Travis M. Davis, Barbara S. Drolet   +3 more
openaire   +4 more sources

Phylogenomic Signatures of a Lineage of Vesicular Stomatitis Indiana Virus Circulating During the 2019-2020 Epidemic in the United States. [PDF]

Viruses
For the first time, we describe phylogenomic signatures of an epidemic lineage of vesicular stomatitis Indiana virus (VSIV). We applied multiple evolutionary analyses to a dataset of 87 full-length genome sequences representing the circulation of an epidemic VSIV lineage in the US between 2019 and 2020.
Zarate S, Bertram M, Rodgers C, Reed K, Pelzel-McCluskey A, Gomez-Romero N, Rodriguez LL, Mayo C, Mire C, Pond SLK, Velazquez-Salinas L.   +10 more
europepmc   +4 more sources

Antigen presentation of post-translationally modified peptides in major histocompatibility complexes. [PDF]

Immunol Cell Biol
T cells recognize pathogens and malignantly transformed cells through antigen presentation on major histocompatibility complex molecules. Post‐translational modifications (PTMs) of proteins can alter the peptides presented, influencing immune recognition and disease.
de Wit AS, Bianchi F, van den Bogaart G.
europepmc   +2 more sources

Assessment of Single-Cycle M-Protein Mutated Vesicular Stomatitis Virus as a Safe and Immunogenic Mucosal Vaccine Platform for SARS-CoV-2 Immunogen Delivery. [PDF]

Adv Sci (Weinh)
The VSVMT‐S2P vaccine candidate, featuring a SARS‐CoV‐2 pre‐fusion state spike protein mutant, is safe in healthy and immunocompromised animals. With only single inoculation via various routes of administration, VSVMT‐S2P can stimulate effective and comprehensive immune responses in vivo, especially via the intramuscular route.
Zhang E, Ke Y, Ran W, Zhang Y, Li R, Fang X, Wang L, Zhang B, Sun T.   +8 more
europepmc   +2 more sources

Using Vesicular Stomatitis Virus as a Platform for Directed Protease Evolution. [PDF]

Curr Protoc
Abstract Antiviral drugs are essential medications to save the lives of infected people. However, they are under constant threat to become ineffective as viruses evolve quickly. Studying the development of resistance is therefore paramount to understand the impact of mutations on pharmacological treatment and to make informed decisions.
Costacurta F, Rauch S, von Laer D, Heilmann E.   +3 more
europepmc   +2 more sources

Comparative analysis of oncolytic potential of vesicular stomatitis virus serotypes Indiana and New Jersey in cancer cell lines

Sechenov Medical Journal, 2023
Aim. Compare the lytic efficiency and the kinetics of accumulation of vesicular stomatitis virus serotypes Indiana (VSV-IND) and New Jersey (VSV-NJ) on cell lines of mouse melanoma B16F10, human hepatocellular carcinoma HepG2 and human mammary adenocarcinoma MCF7.Materials and methods.
A. S. Isaeva, N. O. Porozova, E. Idota, S. I. Volodina, A. N. Lukashev, A. S. Malogolovkin   +5 more
openaire   +3 more sources

Vesicular stomatitis Indiana virus near-full-length genome sequences reveal low genetic diversity during the 2019 outbreak in Colorado, USA. [PDF]

Front Vet Sci, 2023
Bertram MR, Rodgers C, Reed K, Velazquez-Salinas L, Pelzel-McCluskey A, Mayo C, Rodriguez L.   +6 more
europepmc   +2 more sources

Vesicular Stomatitis Virus as a Platform for Protease Activity Measurements. [PDF]

Curr Protoc
Abstract Protease inhibitors are among the most powerful antiviral drugs. They have been used successfully against viruses, such as the human immunodeficiency virus (HIV), hepatitis C virus (HCV) and severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2).
Rauch S, Costacurta F, von Laer D, Heilmann E.   +3 more
europepmc   +2 more sources