Results 51 to 60 of about 24,925 (205)

Nipah shell disorder, modes of infection, and virulence [PDF]

, 2020
The Nipah Virus (NiV) was first isolated during a 1998–9 outbreak in Malaysia. The outbreak initially infected farm pigs and then moved to humans from pigs with a case-fatality rate (CFR) of about 40%.
Dunker, A. Keith, Foster, James A., Goh, Gerard Kian-Meng, Uversky, Vladimir N.   +3 more
core   +1 more source

A real-time reverse transcriptase polymerase chain reaction for detection and quantification of Vesiculovirus

Memorias do Instituto Oswaldo Cruz, 2016
Vesiculoviruses (VSV) are zoonotic viruses that cause vesicular stomatitis disease in cattle, horses and pigs, as well as sporadic human cases of acute febrile illness. Therefore, diagnosis of VSV infections by reliable laboratory techniques is important
Aline Lavado Tolardo, William Marciel de Souza, Marilia Farignoli Romeiro, Luiz Carlos Vieira, Luciano Kleber de Souza Luna, Dyana Alves Henriques, Jansen de Araujo, Carlos Eduardo Hassegawa Siqueira, Tatiana Elias Colombo, Victor Hugo Aquino, Benedito Antonio Lopes da Fonseca, Roberta Vieira de Morais Bronzoni, Maurício Lacerda Nogueira, Edison Luiz Durigon, Luiz Tadeu Moraes Figueiredo   +14 more
doaj   +1 more source

Dose-dependent T-cell Dynamics and Cytokine Cascade Following rVSV-ZEBOV Immunization. [PDF]

, 2017
BACKGROUND: The recent West African Ebola epidemic led to accelerated efforts to test Ebola vaccine candidates. As part of the World Health Organisation-led VSV Ebola Consortium (VEBCON), we performed a phase I clinical trial investigating rVSV-ZEBOV (a ...
Addo, MM, Becker, S, Biedenkopf, N, Borregaard, S, Dahlke, C, Eickmann, M, Fehling, SK, Jambrecina, A, Kasonta, R, Krähling, V, Lohse, AW, Lunemann, S, Ly, ML, Lütgehetmann, M, Olearo, F, Rechtien, A, Schmiedel, S, Spohn, M, Stahl, F, Strecker, T, Stubbe, HC, VEBCON Consortium, Zinser, ME   +22 more
core   +1 more source

Lentivector Producer Cell Lines with Stably Expressed Vesiculovirus Envelopes

Molecular Therapy: Methods & Clinical Development, 2018
Retroviral and lentiviral vectors often use the envelope G protein from the vesicular stomatitis virus Indiana strain (VSVind.G). However, lentivector producer cell lines that stably express VSVind.G have not been reported, presumably because of its ...
Maha Tijani, Altar M. Munis, Christopher Perry, Khaled Sanber, Marta Ferraresso, Tarit Mukhopadhyay, Michael Themis, Ilaria Nisoli, Giada Mattiuzzo, Mary K. Collins, Yasuhiro Takeuchi   +10 more
doaj   +1 more source

Safety and tolerability of HIV-1 multiantigen pDNA vaccine given with IL-12 plasmid DNA via electroporation, boosted with a recombinant vesicular stomatitis virus HIV Gag vaccine in healthy volunteers in a randomized, controlled clinical trial. [PDF]

PLoS ONE, 2018
BACKGROUND:The addition of plasmid cytokine adjuvants, electroporation, and live attenuated viral vectors may further optimize immune responses to DNA vaccines in heterologous prime-boost combinations.
Marnie L Elizaga, Shuying S Li, Nidhi K Kochar, Gregory J Wilson, Mary A Allen, Hong Van N Tieu, Ian Frank, Magdalena E Sobieszczyk, Kristen W Cohen, Brittany Sanchez, Theresa E Latham, David K Clarke, Michael A Egan, John H Eldridge, Drew Hannaman, Rong Xu, Ayuko Ota-Setlik, M Juliana McElrath, Christine Mhorag Hay, NIAID HIV Vaccine Trials Network (HVTN) 087 Study Team   +19 more
doaj   +1 more source

Quantitative Multiplex Assay for Simultaneous Detection and Identification of Indiana and New Jersey Serotypes of Vesicular Stomatitis Virus [PDF]

Journal of Clinical Microbiology, 2005
ABSTRACT In order to establish a rapid and reliable system for the detection of vesicular stomatitis virus (VSV), we developed a quantitative reverse transcription-PCR assay for the detection, quantification, and differentiation of the major serotypes, VSV Indiana and VSV New Jersey, using a closed-tube multiplex format.
Rasmussen, Thomas B., Uttenthal, Åse, Fernández, Jovita, Storgaard, Torben   +3 more
openaire   +4 more sources

The host-range tdCE phenotype of Chandipura virus is determined by mutations in the polymerase gene [PDF]

The emerging arbovirus Chandipura virus (CV) has been implicated in epidemics of acute encephalitis in India with high mortality rates. The isolation of temperature-dependent host-range (tdCE) mutants, which are impaired in growth at 39 °C in chick ...
Easton, A. J. (Andrew J.), Marriott, Anthony C., Stock, Emily   +2 more
core   +1 more source

Vesicular stomatitis virus enables gene transfer and transsynaptic tracing in a wide range of organisms [PDF]

, 2015
Current limitations in technology have prevented an extensive analysis of the connections among neurons, particularly within nonmammalian organisms. We developed a transsynaptic viral tracer originally for use in mice, and then tested its utility in a ...
Baskerville A, Bussereau F, Cajal SR, Fujii H, Garm A, Güntürkün O, Huang L, Johnson KM, Knipe DM, Long GR, Maaswinkel H, Mead DG, Metcalfe WK, Mey J, Nichol ST, Pol AN, Sebesteny T, Tesh R, Wickersham IR, Wyers F, Yasumura Y, Ye Z   +21 more
core   +2 more sources

Risk of infection of dairy cattle in the EU with highly pathogenic avian influenza virus affecting dairy cows in the United States of America (H5N1, Eurasian lineage goose/Guangdong clade 2.3.4.4b. genotype B3.13)

EFSA Journal, Volume 23, Issue 12, December 2025.
Abstract This opinion assesses the risk of avian influenza H5N1 B3.13 genotype virus infection in EU dairy cattle. Introduction of the virus into EU dairy cattle, poultry or wild birds via trade or migratory birds from the US is assessed as highly unlikely.
EFSA Panel on Animal Health and Welfare (AHAW), Julio Alvarez, Anette Ella Boklund, Sabine Dippel, Fernanda Dórea, Jordi Figuerola, Mette S. Herskin, Virginie Michel, Miguel Ángel Miranda Chueca, Eleonora Nannoni, Søren Saxmose Nielsen, Romolo Nonno, Anja B. Riber, Jan Arend Stegeman, Karl Ståhl, Hans‐Hermann Thulke, Frank Tuyttens, Christoph Winckler, Alessio Bortolami, Mariette Ducatez, Claire Guinat, Elsayed M. Abdelwhab, Laurent Guillier, Maarten Nauta, Photis Papademas, Elisabetta Suffredini, Winy Messens, Alessandro Broglia, Helene Jensen, Kamela Kryemadhi, Andrea Gervelmeyer   +30 more
wiley   +1 more source

Use of Heterologous Vesiculovirus G Proteins Circumvents the Humoral Anti-envelope Immunity in Lentivector-Based In Vivo Gene Delivery

Molecular Therapy: Nucleic Acids, 2019
Vesicular stomatitis virus Indiana strain glycoprotein (VSVind.G) mediates broad tissue tropism and efficient cellular uptake. Lentiviral vectors (LVs) are particularly promising, as they can efficiently transduce non-dividing cells and facilitate stable
Altar M. Munis, Giada Mattiuzzo, Emma M. Bentley, Mary K. Collins, James E. Eyles, Yasuhiro Takeuchi   +5 more
doaj   +1 more source