Results 61 to 70 of about 23,388 (157)
Advanced Science, Volume 11, Issue 47, December 18, 2024.The VSVMT‐S2P vaccine candidate, featuring a SARS‐CoV‐2 pre‐fusion state spike protein mutant, is safe in healthy and immunocompromised animals. With only single inoculation via various routes of administration, VSVMT‐S2P can stimulate effective and comprehensive immune responses in vivo, especially via the intramuscular route.
En Zhang +8 more
wiley +1 more source
Using Vesicular Stomatitis Virus as a Platform for Directed Protease Evolution
Current Protocols, Volume 4, Issue 12, December 2024.Abstract Antiviral drugs are essential medications to save the lives of infected people. However, they are under constant threat to become ineffective as viruses evolve quickly. Studying the development of resistance is therefore paramount to understand the impact of mutations on pharmacological treatment and to make informed decisions.
Francesco Costacurta +3 more
wiley +1 more source
A PERSPECTIVE CULTURAL MODEL FOR CONTROL OF BIOLOGICAL ACTIVITY OF HUMAN INTERFERONS
Журнал микробиологии, эпидемиологии и иммунобиологии, 2015 Aim. Study species specificity of human lymphocyte interferon alpha in vitro in cell cultures of swine origin for expansion of cell line spectrum for interferon titration and control of newly created interferons and interferon-like preparations in vivo ...
F. G Nagieva +5 more
doaj
Journal of General Virology, 1986 A full length cDNA copy of the NS mRNA of the Missouri strain (Hazelhurst subtype, New Jersey serotype) of vesicular stomatitis virus (VSV) has been cloned and sequenced. The mRNA is 856 nucleotides long (excluding polyadenylic acid) and encodes a protein of 274 amino acids (mol. wt. 31 000).
B P, Rae, R M, Elliott
openaire +2 more sources
Vesicular Stomatitis Virus as a Platform for Protease Activity Measurements
Current Protocols, Volume 4, Issue 11, November 2024.Abstract Protease inhibitors are among the most powerful antiviral drugs. They have been used successfully against viruses, such as the human immunodeficiency virus (HIV), hepatitis C virus (HCV) and severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2).
Stefanie Rauch +3 more
wiley +1 more source
Vaccine process technology—A decade of progress
Biotechnology and Bioengineering, Volume 121, Issue 9, Page 2604-2635, September 2024.Abstract In the past decade, new approaches to the discovery and development of vaccines have transformed the field. Advances during the COVID‐19 pandemic allowed the production of billions of vaccine doses per year using novel platforms such as messenger RNA and viral vectors.
Barry Buckland +8 more
wiley +1 more source
Xenotransplantation, Volume 31, Issue 3, May/June 2024.Abstract Background The German Xenotransplantation Consortium is in the process to prepare a clinical trial application (CTA) on xenotransplantation of genetically modified pig hearts. In the CTA documents to the central and national regulatory authorities, that is, the European Medicines Agency (EMA) and the Paul Ehrlich Institute (PEI), respectively,
Joachim Denner
wiley +1 more source
International Consensus Statement on Allergy and Rhinology: Sinonasal Tumors
International Forum of Allergy &Rhinology, Volume 14, Issue 2, Page 149-608, February 2024.Abstract Background Sinonasal neoplasms, whether benign and malignant, pose a significant challenge to clinicians and represent a model area for multidisciplinary collaboration in order to optimize patient care. The International Consensus Statement on Allergy and Rhinology: Sinonasal Tumors (ICSNT) aims to summarize the best available evidence and ...
Edward C. Kuan +158 more
wiley +1 more source
Cross-neutralization between vesicular stomatitis virus type Indiana and Chandipura virus.
Acta virologica, 1979 Using highly potent immune sheep sera, it was possible to demonstrate that: (1) Two rhabdoviruses, classified in the Vesiculovirus genus on morphological grounds but previously considered unrelated, viz., the vesicular stomatitis virus type Indiana (VSV), and Chandipura virus (ChV), show a low-level, but distinct cross-neutralization. This was, in most
J, Dragúnová, J, Závada
openaire +1 more source
An Unconventional Case Study of Neoadjuvant Oncolytic Virotherapy for Recurrent Breast Cancer
VaccinesIntratumoural oncolytic virotherapy may have promise as a means to debulk and downstage inoperable tumours in preparation for successful surgery. Here, we describe the unique case of a 50-year-old self-experimenting female virologist with locally ...
Dubravko Forčić +8 more
doaj +1 more source