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Vesicular Stomatitis Virus: From Agricultural Pathogen to Vaccine Vector
Pathogens, 2021 Vesicular stomatitis virus (VSV), which belongs to the Vesiculovirus genus of the family Rhabdoviridae, is a well studied livestock pathogen and prototypic non-segmented, negative-sense RNA virus.
Guodong Liu +6 more
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Vesicular Stomatitis Virus Transmission Dynamics Within Its Endemic Range in Chiapas, Mexico [PDF]
VirusesVesicular stomatitis virus (VSV), comprising vesicular stomatitis New Jersey virus (VSNJV) and vesicular stomatitis Indiana virus (VSIV), emerges from its focus of endemic transmission in Southern Mexico to cause sporadic livestock epizootics in the ...
Lawrence H. Zhou +12 more
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Protective Efficacy of Lyophilized Vesicular Stomatitis Virus–Based Vaccines in Animal Model [PDF]
Emerging Infectious DiseasesWe evaluated the in vitro effects of lyophilization for 2 vesicular stomatitis virus–based vaccines by using 3 stabilizing formulations and demonstrated protective immunity of lyophilized/reconstituted vaccine in guinea pigs.
Abd’jeleel Salawudeen +7 more
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The Antigens of Vesicular Stomatitis Virus [PDF]
The Journal of Immunology, 1966 Summary The infective component of vesicular stomatitis virus was purified by ammonium sulfate precipitation, differential ultracentrifugation and sucrose density gradient centrifugation and then treated with Tween-ether. This treatment reduced the infectivity of the preparation by ca.
F. Brown, B. Cartwright
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TRIM69 Inhibits Vesicular Stomatitis Indiana Virus [PDF]
Journal of Virology, 2019 Vesicular stomatitis Indiana virus (VSIV) is a veterinary pathogen that is also used as a backbone for many oncolytic and vaccine strategies. In natural and therapeutic settings, viral infections like VSIV are sensed by the host, and as a result the host
Suzannah J. Rihn +11 more
semanticscholar +4 more sources
Model for Vesicular Stomatitis Virus [PDF]
Journal of Virology, 1972 Vesicular stomatitis virus contains single-stranded ribonucleic acid of molecular weight 3.6 × 10 6 and three major proteins with molecular weights of 75 × 10 3 , 57 × 10 3 , and 32.5 × 10 3 .
B. Cartwright +3 more
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Fitness Determinations in Vesicular Stomatitis Virus [PDF]
Bio-Protocol, 2014 Fitness is defined as the overall replicative ability. Testing whether a mutation (or combination of mutations) has an effect on fitness often relays on determining virus production as a surrogate measurement. However, viruses do not usually replicate in
Isabel Novella
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Vesicular Stomatitis Virus–Based Vaccines against Lassa and Ebola Viruses
Emerging Infectious Diseases, 2015 We demonstrated that previous vaccination with a vesicular stomatitis virus (VSV)–based Lassa virus vaccine does not alter protective efficacy of subsequent vaccination with a VSV-based Ebola virus vaccine.
Andrea Marzi +4 more
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Surface Structure of Vesicular Stomatitis Virus
Journal of General Virology, 1969 Summary Trypsin (0.1 mg./ml.) reduced the infectivity of vesicular stomatitis virus by 5 log. within 5 min. and destroyed immunizing activity. It also destroyed the complement-fixing activity against antiserum to the virus but the activity against antiserum to host cells was unaffected.
B. Cartwright, C. J. Smale, F. Brown
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Atomic model of vesicular stomatitis virus and mechanism of assembly [PDF]
Nature Communications, 2022 Zhou and Si et al. used cryogenic electron microscopy and tomography to delineate the molecular interactions among genomic RNA, nucleocapsid protein, matrix protein and glycoprotein in vesicular stomatitis virus and suggest a model of assembly.
Kang Zhou +5 more
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