Results 21 to 30 of about 80,112 (305)

Integrin Alpha E (CD103) Limits Virus-Induced IFN-I Production in Conventional Dendritic Cells

open access: yesFrontiers in Immunology, 2021
Early and strong production of IFN-I by dendritic cells is important to control vesicular stomatitis virus (VSV), however mechanisms which explain this cell-type specific innate immune activation remain to be defined.
Vikas Duhan   +24 more
doaj   +1 more source

The synthetic futures of vesicular stomatitis virus [PDF]

open access: yesTrends in Biotechnology, 2012
Recent advances in synthetic biology have opened up the possibility of finely engineering viral genomes with the goal to understand and prevent viral diseases [1]. Vesicular stomatitis virus (VSV) is one of the most promising viruses for engineering vaccines and oncolytic therapies [2].
Christopher Overend   +3 more
openaire   +3 more sources

CONSTRUCTION AND STUDY OF Althaea officinalis TRANSGENIC ROOTS CULTURE WITH HUMAN INTERFERON α2B GENE [PDF]

open access: yesBiotechnologia Acta, 2013
The aim of our work was to obtain Althaea officinalis L. «hairy» root culture with human interferon α2b gene (ifn-α2b), to measure fructans content and antiviral activity of extracts from the transgenic roots. Transformation of leaf and root explants was
N. A. Matvieieva   +4 more
doaj   +1 more source

Carbohydrate Composition of Vesicular Stomatitis Virus [PDF]

open access: yesJournal of Virology, 1971
Analysis by gas-liquid chromatography of the trimethylsilylated sugar residues of purified vesicular stomatitis virus grown in L cells or chick embryo cells revealed the presence in the whole virion of four hexoses (glucose, galactose, mannose, and fucose), two hexosamines (glucosamine and galactosamine), and 34 to 40% neuraminic acid.
Robert R. Wagner, James J. McSharry
openaire   +3 more sources

A VSV-based assay quantifies coronavirus Mpro/3CLpro/Nsp5 main protease activity and chemical inhibition

open access: yesCommunications Biology, 2022
A vesicular stomatitis virus (VSV)-based assay enables high-throughput screening for small molecular protease inhibitors that can block viral proteases, like the Mpro/3CLpro/Nsp5 in SARS-CoV-2.
Emmanuel Heilmann   +7 more
doaj   +1 more source

Isolation of the envelope of vesicular stomatitis virus [PDF]

open access: yesJournal of Virology, 1978
Vesicular stomatitis virus was disrupted by a combination of freezing and thawing, osmotic shock, and sonic treatment. Subviral components were separated by isopycnic centrifugation. The low-density, lipid-rich fractions were pooled and shown to contain primarily viral glycoprotein.
S E Taube, L I Rothfield
openaire   +3 more sources

Examination of vesicular stomatitis virus-induced morphology changes in individual Vero cells by QMod microscopy

open access: yesBioTechniques, 2020
Viral infection of cultured cells induces changes in the biophysical characteristics of the affected cells. Advanced microscopic cameras such as Ovizio’s QMod, coupled with the appropriate software, can measure a variety of characteristics on a per-cell ...
Isabel Scholz   +2 more
doaj   +1 more source

The nucleocapsid of vesicular stomatitis virus [PDF]

open access: yesScience China Life Sciences, 2012
The nucleocapsid of vesicular stomatitis virus serves as the genomic template for transcription and replication. The viral genomic RNA is sequestered in the nucleocapsid in every step of the virus replication cycle. The structure of the nucleocapsid and the entire virion revealed how the viral genomic RNA is encapsidated and packaged in the virus.
openaire   +3 more sources

Aptamer-facilitated Protection of Oncolytic Virus from Neutralizing Antibodies

open access: yesMolecular Therapy: Nucleic Acids, 2014
Oncolytic viruses promise to significantly improve current cancer treatments through their tumor-selective replication and multimodal attack against cancer cells.
Darija Muharemagic   +6 more
doaj   +1 more source

Use of recombinant virus replicon particles for vaccination against Mycobacterium ulcerans disease [PDF]

open access: yes, 2015
Buruli ulcer, caused by infection with Mycobacterium ulcerans, is a necrotizing disease of the skin and subcutaneous tissue, which is most prevalent in rural regions of West African countries.
Bolz, Miriam   +3 more
core   +3 more sources

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