Results 51 to 60 of about 83,240 (318)

Oncotargeting by Vesicular Stomatitis Virus (VSV): Advances in Cancer Therapy

Viruses, 2018
Modern oncotherapy approaches are based on inducing controlled apoptosis in tumor cells. Although a number of apoptosis-induction approaches are available, site-specific delivery of therapeutic agents still remain the biggest hurdle in achieving the ...
S. Bishnoi, Ritudhwaj Tiwari, Sharad Gupta, S. Byrareddy, D. Nayak   +4 more
semanticscholar   +1 more source

Safety of Recombinant VSV–Ebola Virus Vaccine Vector in Pigs

Emerging Infectious Diseases, 2015
The ongoing Ebola outbreak in West Africa has resulted in fast-track development of vaccine candidates. We tested a vesicular stomatitis virus vector expressing Ebola virus glycoprotein for safety in pigs.
Emmie de Wit, Andrea Marzi, Trenton Bushmaker, Doug Brining, Dana Scott, Juergen A. Richt, Thomas W. Geisbert, Heinz Feldmann   +7 more
doaj   +1 more source

The nucleocapsid of vesicular stomatitis virus [PDF]

Science China Life Sciences, 2012
The nucleocapsid of vesicular stomatitis virus serves as the genomic template for transcription and replication. The viral genomic RNA is sequestered in the nucleocapsid in every step of the virus replication cycle. The structure of the nucleocapsid and the entire virion revealed how the viral genomic RNA is encapsidated and packaged in the virus.
openaire   +2 more sources

Frequency analysis of cytolytic T lymphocyte precursors (CTL-P) generated in vivo during lethal rabies infection of mice. II. Rabies virus genus specificity of CTL-P [PDF]

, 1984
Cytolytic T lymphocyte precursors (CTL-P) were sensitized in vivo by intraplantar infection of C57BL/6 mice with a lethal dose of rabies virus, strain ERA (ERA).
Aden, Baer, Berke, Cox, Fazekas De, Grimm, Koprowski, Minato, Reddehase, Reddehase, Reddehase, Rosenthal, Rosenthal, Schneider, Sethi, Shope, Shope, Stoker, Taswell, Wiktor, Wiktor, Zinkernagel, Zinkernagel   +22 more
core   +1 more source

Protocol for constructing and characterizing recombinant vectored vaccines for rabies virus

STAR Protocols
Summary: Recombinant vectored vaccines provide economical, rapidly engineered, and tailored immunization strategies. Here, we present a protocol for constructing and characterizing recombinant vectored vaccines for rabies virus (RV).
Manar E. Khalifa, Muhammad Munir
doaj   +1 more source

Eradication of Swine Vesicular Disease in Italy

Viruses, 2020
Swine vesicular disease (SVD) is a contagious viral disease of pigs clinically indistinguishable from other vesicular diseases, such as foot and mouth disease, vesicular stomatitis, vesicular exanthema of swine, and idiopathic vesicular disease. In Italy,
Marco Tamba, Francesco Plasmati, Emiliana Brocchi, Luigi Ruocco   +3 more
doaj   +1 more source

Fusogenic vesicular stomatitis virus combined with natural killer T cell immunotherapy controls metastatic breast cancer. [PDF]

Breast Cancer Res
Nelson A, McMullen N, Gebremeskel S, De Antueno R, Mackenzie D, Duncan R, Johnston B.   +6 more
europepmc   +3 more sources

Vesicular Stomatitis Virus: Mode of Transcription

Journal of General Virology, 1977
Recent studies on the mechanism by which the virion-associated RNA polymerase of vesicular stomatitis virus transcribes RNA have revealed several new biological features of general interest. The mode of synthesis of the 5'-terminal cap structure of the mRNAs, the sequential transcription of the genes and the presence of a transcribed "leader" RNA ...
A D, Banerjee, G, Abraham, R J, Colonno
openaire   +2 more sources

Oncolytic vesicular stomatitis virus expressing interferon-γ has enhanced therapeutic activity

Molecular Therapy: Oncolytics, 2016
Oncolytic viruses are known to stimulate the antitumor immune response by specifically replicating in tumor cells. This is believed to be an important aspect of the durable responses observed in some patients and the field is rapidly moving toward ...
M. Bourgeois-Daigneault, D. Roy, T. Falls, K. Twumasi-Boateng, L. E. St-Germain, M. Marguerie, Vanessa García, M. Selman, V. Jennings, Jessica L Pettigrew, Sally M. Amos, J. Diallo, B. Nelson, J. Bell   +13 more
semanticscholar   +1 more source

Crystal structure of Schmallenberg orthobunyavirus nucleoprotein-RNA complex reveals a novel RNA sequestration mechanism [PDF]

, 2013
Schmallenberg virus (SBV) is a newly emerged orthobunyavirus (family Bunyaviridae) that has caused severe disease in the offspring of farm animals across Europe.
Bottcher, B., Dong, C., Dong, H., Elliott, R., Li, P.   +4 more
core   +1 more source