Results 51 to 60 of about 80,112 (305)

Evaluating Temperature Sensitivity of Vesicular Stomatitis Virus–Based Vaccines

open access: yesEmerging Infectious Diseases, 2019
Use of the vesicular stomatitis virus (VSV)–based Ebola virus vaccine during outbreaks and the potential use of a similar VSV-based Lassa virus vaccine has raised questions about the vaccines’ stability should the cold chain fail.
Derek R. Stein   +5 more
doaj   +1 more source

Single virus fingerprinting by widefield interferometric defocus-enhanced mid-infrared photothermal microscopy

open access: yesNature Communications, 2023
Clinical identification and fundamental study of viruses rely on the detection of viral proteins or viral nucleic acids. Yet, amplification-based and antigen-based methods are not able to provide precise compositional information of individual virions ...
Qing Xia   +8 more
doaj   +1 more source

Preparation of Class Y Immunoglobulins that Neutralize the Marburg Virus

open access: yesПроблемы особо опасных инфекций, 2021
The aim was to study the possibility of inducing Marburg-neutralizing chicken antibodies (MARV) using various immunogens.Materials and methods. Recombinant vaccinia virus expressing the surface glycoprotein (GP) transgene MARV of Musoke strain and ...
O. A. Polezhaeva   +7 more
doaj   +1 more source

Oncotargeting by Vesicular Stomatitis Virus (VSV): Advances in Cancer Therapy

open access: yesViruses, 2018
Modern oncotherapy approaches are based on inducing controlled apoptosis in tumor cells. Although a number of apoptosis-induction approaches are available, site-specific delivery of therapeutic agents still remain the biggest hurdle in achieving the ...
S. Bishnoi   +4 more
semanticscholar   +1 more source

Inhibition of translation by poliovirus: Inactivation of a specific initiation factor [PDF]

open access: yes, 1978
Translation of vesicular stomatitis virus (VSV) mRNA, like host mRNA translation, is inhibited in cells infected with poliovirus. To study the mechanism of poliovirus-induced inhibition of protein synthesis, we prepared extracts from poliovirus-infected ...
Baltimore, David   +3 more
core   +1 more source

Oncolytic Vesicular Stomatitis Virus as a Viro-Immunotherapy: Defeating Cancer with a “Hammer” and “Anvil”

open access: yesBiomedicines, 2017
Oncolytic viruses have gained much attention in recent years, due, not only to their ability to selectively replicate in and lyse tumor cells, but to their potential to stimulate antitumor immune responses directed against the tumor. Vesicular stomatitis
M. Melzer   +2 more
semanticscholar   +1 more source

A two-step lyssavirus real-time polymerase chain reaction using degenerate primers with superior sensitivity to the fluorescent antigen test [PDF]

open access: yes, 2014
A generic two-step lyssavirus real-time reverse transcriptase polymerase chain reaction (qRT-PCR), based on a nested PCR strategy, was validated for the detection of different lyssavirus species.
De Craeye, Stéphane   +6 more
core   +4 more sources

Safety of Recombinant VSV–Ebola Virus Vaccine Vector in Pigs

open access: yesEmerging Infectious Diseases, 2015
The ongoing Ebola outbreak in West Africa has resulted in fast-track development of vaccine candidates. We tested a vesicular stomatitis virus vector expressing Ebola virus glycoprotein for safety in pigs.
Emmie de Wit   +7 more
doaj   +1 more source

Eradication of Swine Vesicular Disease in Italy

open access: yesViruses, 2020
Swine vesicular disease (SVD) is a contagious viral disease of pigs clinically indistinguishable from other vesicular diseases, such as foot and mouth disease, vesicular stomatitis, vesicular exanthema of swine, and idiopathic vesicular disease. In Italy,
Marco Tamba   +3 more
doaj   +1 more source

Emergency postexposure vaccination with vesicular stomatitis virus-vectored Ebola vaccine after needlestick.

open access: yesJournal of the American Medical Association (JAMA), 2015
IMPORTANCE Safe and effective vaccines and drugs are needed for the prevention and treatment of Ebola virus disease, including following a potentially high-risk exposure such as a needlestick. OBJECTIVE To assess response to postexposure vaccination in
L. Lai   +18 more
semanticscholar   +1 more source

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