Results 141 to 150 of about 42,252 (217)

The Promise of Single-Domain Antibodies as Ocular Therapeutics: A Narrative Review. [PDF]

Int J Mol Sci
Jakobsen TS, Kaptain K, Pedersen K, Adsersen RL, Aagaard L, Askou AL, Corydon TJ.   +6 more
europepmc   +1 more source

Predicting non-specific binding of VHHs using machine learning models with cluster-aware validation. [PDF]

MAbs
Stanev V, Devalle F, Boroumand M, Pouryahya M, Sermadiras I, Caldwell J, Chen KL, Jo JH, Jain R, Amofah B, Pham T, Hutchinson M, Farzandh S, DiChiara J, Chakiath C, Diethe T, Dippel A, Kaplan G, Croasdale-Wood R.   +18 more
europepmc   +1 more source

Integrating AlphaFold2 with physics-based ensemble docking for high-efficiency nanobody discovery. [PDF]

Chem Sci
Guo Y, Guan R, Jin L, Zhang J, Wu W, Sun R, Li B, Cao R, Jia H, Liu L, Xing W, Ma J, Sun B.   +12 more
europepmc   +1 more source

Functional Suitability Evaluation of Radioimmunoconjugates of Nanobodies against PD-L1 and HER2/neu for Tumor Theranostics. [PDF]

Sovrem Tekhnologii Med
Avrov KO, Shatik SV, Shashkova OA, Pinevich AA, Terekhina LA, Gryazeva IV, Zaitsev VV, Berlina MA, Stanzhevsky AA, Samoylovich MP.   +9 more
europepmc   +1 more source

Entire VHH-MMSI completed

Integration of media analytics components with the VHH Media Management and Search Infrastructure is completed and the entire VHH-MMSI is finalised.
openaire   +1 more source

Predicting antibody self-association with sequence-structure fusion models: the central role of CSI-BLI in early developability screening. [PDF]

MAbs
Ahmed S, Devalle F, Leisen L, Pham T, Amofah B, Lee A, Hutchinson M, Chakiath C, DiChiara J, Farzandh S, Kreitz M, Hinton A, Mody N, Dippel A, Kaplan G, Pouryahya M.   +15 more
europepmc   +1 more source

Artificial intelligence-assisted design of MAGE-A4 ×CD16 T-cell receptor-like natural killer cell engagers. [PDF]

MAbs
Liu Y, Peng H, Fan X, Liu X, Jiao G, Li J, Wang T, Fong SJ, Zhu L, Dai Y, Zhao Q.   +10 more
europepmc   +1 more source

VHHs as therapeutic tools in tauopathy models

Les tauopathies sont un groupe de maladies neurodégénératives hétérogènes ayant pour caractéristique commune une accumulation intracellulaire d'agrégats composés de protéine tau. Dans la maladie d'Alzheimer, la pathologie tau évolue selon une progression stéréotypée, connue sous le nom de stade de Braak. Aujourd’hui ces stades sont considérés comme les
openaire   +2 more sources

Potent neutralization and therapeutic efficacy of bovine rotavirus-specific VHH antibodies in infected calves. [PDF]

Vet Res
Zhao Q, Gao M, Li P, Wang B, Li B, Rile G, Du C, Wang J, Wang H, Mei J, Zhang S, Bao F.   +11 more
europepmc   +1 more source

Parallelised Cloning, Mammalian Cell Expression, and Purification of Nanobodies Identified by Phage Display. [PDF]

Bio Protoc
Campaigne HA, Parker KL, Owens RJ, Eyssen LE.   +3 more
europepmc   +1 more source