Results 141 to 150 of about 58,013 (257)

Neutralization of the Pandemic Influenza A/H1N1 Virus with Lama glama Humanized Nanobodies (VHH)

Antibodies
Background/Objetives: Nanobodies (VHH) have become an excellent tool for diagnosis, therapy, and research since VHH shows a high capability of recognizing and neutralizing antigens.
Zeila Yazmín Páez-Hernández, Jose Luis Stephano-Hornedo, Jose Alberto Bolaños-Prats, Iván Córdova-Guerrero, Mariana Macías-Alonso, Joaquín G. Marrero, Angel Pulido Capiz, Victor García González   +7 more
doaj   +1 more source

Risk sharing: private insurance markets or redistributive taxes? [PDF]

We explore the welfare consequences of different taxation schemes in an economy where agents are debt-constrained. If agents default on their debt, they are banned from future credit markets, but retain their private endowments which are subject to ...
Dirk Krueger, Fabrizio Perri
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Asymmetric Taxation under Incremental and Sequential Investment [PDF]

This article discusses the effects of an asymmetric tax scheme on incremental and sequential investment strategies. The tax base is equal to the firm’s return, net of an imputation rate.
Paolo Panteghini
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The Existence and Asymptotic Properties of a Backfitting Projection Algorithm Under Weak Conditions [PDF]

We derive the asymptotic distribution of a new backfitting procedure for estimating the closest additive approximation to a nonparametric regression function.
E. Mammen, J. Nielsen, Oliver Linton
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Transdermal Administration of Nanobody Molecules using Hydrogel‐Forming Microarray Patch Technology: A Unique Delivery Approach

Macromolecular Materials and Engineering
Nanobody molecules, derived from heavy‐chain only antibodies in camelids, represent the next generation of biotherapeutics. In addition to low immunogenicity, high stability, and potency, their single‐domain format facilitates the construction of ...
Aaron R. J. Hutton, Melissa Kirkby, Tom Van Bogaert, Peter Casteels, Christelle Nonne, Veronique De Brabandere, Ortwin Van deVyver, Lalit K. Vora, Ismaiel A. Tekko, Helen O. McCarthy, Ryan F. Donnelly   +10 more
doaj   +1 more source

Customer Loyalty and Supplier Strategies for Quality Competition [PDF]

We analyze a model of consumer response to variation in product or service quality. The model, developed in [4], provides closed-form expressions that characterize short-term and long-term measures of customer loyalty to a supplier.
Noah Gans
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Vector-valued Coherent Risk Measures [PDF]

We define a coherent risk measures as set-valued maps satisfying some axioms. We show that this definition is a convenient extension of the real-valued risk measures introduced by Artzner, Delbaen, Eber and Heath (1998).
Elyès Jouini, Moncef Meddeb, Nizar Touzi   +2 more
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Biparatopic anti-PCSK9 antibody enhances the LDL-uptake in HepG2 cells

Scientific Reports
Proprotein convertase subtilisin/kexin type 9 (PCSK9) has emerged as a promising therapeutic target to reduce lipids. In 2020, we reported a chimeric camelid-human heavy chain antibody VHH-B11-Fc targeting PCSK9.
Xinyang Li, Wei Zhang, Yu Shu, Rui Huo, Chengyang Zheng, Qi Qi, Pengfei Fu, Jie Sun, Yuhuan Wang, Yan Wang, Juxu Lu, Xiangjie Zhao, Guoyou Yin, Qingqing Wang, Jun Hong   +14 more
doaj   +1 more source

ALTRUISM VS. EXCHANGE IN INTERGENERATIONAL TRANSFERS: NEW EVIDENCE FROM CHILDREN'S HEALTH CARE [PDF]

We put in perspective two competing hypothesis on the nature of intergenerational transfers: altruism vs. exchange motivation. Unlike previous approaches, we concentrate on non-monetary transfers measured as the effort that parents need to make in order ...
Andrés Romeu, Ignacio Ortuño Ortín
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International and Domestic Collateral Constraints in a Model of Emerging Market Crises [PDF]

We build a model of emerging markets crises which features two types of collateral constraints. Firms in a domestic economy have limited borrowing capacity from international investors. They also have limited borrowing capacity with respect to each other.
Arvind Krishnamurthy, Ricardo Caballero
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