Results 31 to 40 of about 14,898 (265)
Safety profile of oxcarbazepine: results from a prescription-event monitoring study [PDF]
, 2010 Purpose: To monitor safety of oxcarbazepine, prescribed in primary care in England, using prescription-event monitoring (PEM). Methods: Postmarketing surveillance using observational cohort technique of PEM.
Buggy, Y. +3 more
core +1 more source
Optimized Treatment for Infantile Spasms: Vigabatrin versus Prednisolone versus Combination Therapy
Journal of Clinical Medicine, 2019 Hormone therapies and vigabatrin are first-line agents in infantile spasms, but more than one-third of patients fail to respond to these treatments. This was a retrospective study of patients with infantile spasms who were treated between January 2005 ...
J. Hahn +6 more
semanticscholar +1 more source
Visual evoked potentials in succinate semialdehyde dehydrogenase (SSADH) deficiency [PDF]
, 2009 In mammals, increased GABA in the central nervous system has been associated with abnormalities of visual evoked potentials (VEPs), predominantly manifested as increased latency of the major positive component P100.
Blasi, P +7 more
core +1 more source
Infantile spasms (West syndrome): update and resources for pediatricians and providers to share with parents [PDF]
, 2012 Background Infantile spasms (IS; West syndrome) is a severe form of encephalopathy that typically affects infants younger than 2 years old. Pediatricians, pediatric neurologists, and other pediatric health care providers are all potentially key early ...
Gibson, Patricia A. +6 more
core +2 more sources
Does the Swedish Interactive Threshold Algorithm (SITA) accurately map visual field loss attributed to vigabatrin? [PDF]
, 2014 Purpose Vigabatrin (VGB) is an anti-epileptic medication which has been linked to peripheral constriction of the visual field. Documenting the natural history associated with continued VGB exposure is important when making decisions about the risk and
Conway, M. L. +3 more
core +3 more sources
Acute vigabatrin-phenobarbitone-interaction on exploratory behaviour of rats [PDF]
, 1996 Vigabatrin (gamma-vinyl GABA) is an irreversible inh:bitor of the enzyme GABA-transaminase (GABA-T) which is responsible for the catabolism of the major inhibitory neurotransmitter gamma- aminobutyric acid (GABA) in the brain. Vigabatrin causes a several
EI-Hwuegi, Abudalla S. +2 more
core
Epileptic Disorders, EarlyView.Abstract The ILAE Neuroimaging Task Force aims to publish educational case reports that highlight basic aspects of neuroimaging in epilepsy consistent with the ILAE's educational mission. Here, we describe a case series of three neonates with focal cortical dysplasia (FCD)‐related drug‐resistant epilepsy who underwent surgical intervention. The purpose
Nathan T. Cohen +18 more
wiley +1 more source
Neuropathology of vigabatrin. [PDF]
British Journal of Clinical Pharmacology, 1989 1. Neuropathological changes in experimental animals have been observed with vigabatrin treatment in mice, rats and dogs. 2. These changes have comprised intramyelinic oedema which is reversible on cessation of treatment. 3. In human studies so far, no intramyelinic oedema has been noted.
openaire +3 more sources
Epileptic spasms - 175 years on: Trying to teach an old dog new tricks [PDF]
, 2017 PURPOSE: This text provides an overview of how the condition "infantile spasms" has evolved in the last 175 years. METHOD: Key references are summarised to assimilate this review.
Ibekwe, RC +2 more
core +1 more source
Epilepsy syndromes classification
Epilepsia Open, EarlyView.Abstract Epilepsy syndromes are distinct electroclinical entities which have been recently defined by the International League Against Epilepsy Nosology and Definitions Task Force. Each syndrome is associated with “a characteristic cluster of clinical and EEG features, often supported by specific etiologic findings”.
Elaine C. Wirrell +4 more
wiley +1 more source