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Perinuclear mRNA localisation by vimentin 3′-untranslated region requires a 100 nucleotide sequence and intermediate filaments [PDF]
The role of the vimentin 3′-untranslated region (3′-UTR) in mRNA localisation was studied in cells transfected with a reporter sequence linked to subregions of the 3′-UTR.
Giovanna Bermano +2 more
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VIMENTIN INTERMEDIATE FILAMENTS IN CULTURES OF HUMAN MENINGIOMAS
Neuropathology and Applied Neurobiology, 1984Monolayer cultures of six human meningiomas and meningeal cells from a human foetus were examined by indirect immunofluorescence with a human autoantibody to intermediate filaments and with a monoclonal antibody to vimentin intermediate filaments. No difference could be demonstrated in the staining of an intricate fibrillar network in cultures of ...
S J, Lolait +7 more
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Mechanics of vimentin intermediate filaments
2003It is increasingly evident that the cytoskeleton of living cells plays important roles in mechanical and biological functions of the cells. Here we focus on the contribution of intermediate filaments (IFs) to the mechanical behaviors of living cells. Vimentin, a major structural component of IFs in many cell types, is shown to play an important role in
Ning, Wang, Dimitrijie, Stamenovic
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Nanomechanical properties of vimentin intermediate filament dimers
Nanotechnology, 2009The cell's cytoskeleton, providing the cell with structure and shape, consists of a complex array of structural proteins, including microtubules, microfilaments and intermediate filaments. Intermediate filaments play a crucial role in mechanotransduction and in providing mechanical stability to cells, in particular under large deformation. By utilizing
Zhao, Qin +2 more
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The unconventional role of vimentin intermediate filaments
Current Opinion in Cell BiologyVimentin, a type III intermediate filament (IF) protein, is well-recognized for its role at the intersection of structural biology and cellular dynamics, influencing various pathways that determine cell fate and function. While these functions have been extensively characterized, there is still limited understanding of vimentin's broader impact beyond ...
Xinyi Huang +6 more
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Vimentin: the conundrum of the intermediate filament gene family
BioEssays, 1998Intermediate filaments are a major component of the "cytoskeleton" of "higher" eukaryotes. These filaments are composed of a number of different, although structurally related, proteins. Different intermediate filament protein genes are expressed in different tissues.
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Coalignment of vimentin intermediate filaments with microtubules depends on kinesin
Nature, 1991Intermediate filaments in most types of cultured cells coalign with microtubules. Depolymerization of microtubules results in collapse of vimentin and desmin intermediate filaments to the nucleus where they form a perinuclear cap. Collapse can also be induced by microinjection of antibodies against intermediate filament or microtubule proteins.
F K, Gyoeva, V I, Gelfand
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Expression of vimentin intermediate filament in human odontoblast.
Minerva stomatologica, 2000Vimentin (57 Kda) is a cytoskeletal protein. Odontoblasts contain vimentin and it seems that this protein may function to keep the organelles and the nucleus in a definite place. However little is known about vimentin in the cytoskeleton of odontoblast processes.
MARTINEZ G +3 more
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Intermediate vimentin filaments and their role in intracellular organelle distribution
Biochemistry (Moscow), 2008Intermediate filaments (IF) represent one of three main cytoskeletal structures in most animal cells. The human IF protein family includes about 70 members divided into five main groups. The characteristic feature of IF is that in various cells and tissues they are formed by proteins of different groups.
A A, Minin, M V, Moldaver
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Unique Role of Vimentin in the Intermediate Filament Proteins Family
Biochemistry (Moscow)Intermediate filaments (IFs), being traditionally the least studied component of the cytoskeleton, have begun to receive more attention in recent years. IFs are found in different cell types and are specific to them. Accumulated data have shifted the paradigm about the role of IFs as structures that merely provide mechanical strength to the cell.
Irina B, Alieva +5 more
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