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Multi-Targeted Mechanisms of Phytochemicals in Mitigating Cadmium-Induced Breast Cancer. [PDF]
Medicines (Basel)Fidudusola FF +5 more
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Chemotherapy-induced peripheral neuropathy in breast cancer: a narrative review. [PDF]
Transl Breast Cancer ResBrodsky M, Lalla M, Oh S, Anampa JD.
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Antitumor natural products targeting mitochondrial NADH: ubiquinone oxidoreductase (complex I): a review. [PDF]
Front PharmacolGou J +7 more
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Reduction of Toxicity of a Vinca Alkaloid by an Anti-Vinca Alkaloid Antibody
Cancer Investigation, 1995Inadvertent oncolytic overdoses occur rarely, but can have serious consequences. We have investigated the possibility of using an antibody, 27.8.1A, reactive with vinca alkaloids, as a means of reducing the toxicity associated with overdose situations.
M C, Gutowski +3 more
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2010
The periwinkle plant, Cantharanthus roseus G. Don (Vinca rosea Linn.) is endemic to the island of Madagascar, and has long been ascribed a wide assortment of medicinal properties ranging from the treatment of diabetes to wound healing. Of the over fifty alkaloids present in minute quantities within the plant, only two (vincristine and vinblastine) have
Nicole Coufal, Lauge Farnaes
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The periwinkle plant, Cantharanthus roseus G. Don (Vinca rosea Linn.) is endemic to the island of Madagascar, and has long been ascribed a wide assortment of medicinal properties ranging from the treatment of diabetes to wound healing. Of the over fifty alkaloids present in minute quantities within the plant, only two (vincristine and vinblastine) have
Nicole Coufal, Lauge Farnaes
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1975
The vinca alkaloids are antineoplastic indole derivatives (Fig. 1) that are isolated from the leaves of the periwinkle plant, Vinca rosea L., or more correctly, Catharanthus roseus G. Don. This plant is of Madagascan origin, although its distribution is now pantropical (Stearn, 1975).
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The vinca alkaloids are antineoplastic indole derivatives (Fig. 1) that are isolated from the leaves of the periwinkle plant, Vinca rosea L., or more correctly, Catharanthus roseus G. Don. This plant is of Madagascan origin, although its distribution is now pantropical (Stearn, 1975).
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The Mode of Action of Vinca Alkaloids
Oncology, 2009P388 leukemia-bearing mice were given a single i.p. injection of [14C]-vincristine and the levels of radioactivity in the tumors and host tissues were determined as a function of time. The highest levels of radioactivity were found in the gallbladder followed by the tumor, spleen and liver, respectively.
O, Csuka +3 more
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