Results 81 to 90 of about 16,117 (210)
ChemistryOpen, Volume 15, Issue 4, April 2026.A novel series of 1,5‐dihydro‐[1,2,4]triazolo[4,3‐a]pyrimidines (5a–g) is synthesized and evaluated as potential CDK4 inhibitors. Compounds 5c and 5d exhibit strong cytotoxicity toward HepG2 and MCF‐7 cells with IC50 ≈ 1–2 µM, comparable to doxorubicin.
Tariq Z. Abolibda +7 more
wiley +1 more source
P-glycoprotein inhibitors of natural origin as potential tumor chemo-sensitizers: A re
Journal of Advanced Research, 2015 Resistance of solid tumors to treatment is significantly attributed to pharmacokinetic reasons at both cellular and multi-cellular levels. Anticancer agent must be bio-available at the site of action in a cytotoxic concentration to exert its proposed ...
Hossam M. Abdallah +3 more
doaj +1 more source
Asia-Pacific Journal of Clinical Oncology, Volume 22, Issue 2, Page 186-198, April 2026.Skin adverse events (AEs) frequently accompany all types of anticancer treatments. This publication discusses how recent international guidance on best‐practices use of dermocosmetics can be adapted to the North Asia region (China, Hong Kong, Japan, Republic of Korea, and Taiwan).
Meng Pan +9 more
wiley +1 more source
Establishment and characterization of an etoposide-resistant human small cell lung cancer cell line. [PDF]
, 1992 An etoposide-resistant subline, SBC-3/ETP, from a human small cell lung cancer cell line, SBC-3, was developed by continuous exposure to increasing concentrations of etoposide in culture.
Kimura, Ikuro +4 more
core +1 more source
Ibrain, Volume 12, Issue 1, Page 65-85, Spring 2026.Chemotherapy‐induced peripheral neuropathy (CIPN) remains a major clinical challenge, with central sensitization considered an important pathological mechanism in its occurrence and persistence. This review focuses on spinal astrocytes and microglia, systematically summarizing the pathological mechanisms of spinal glial cells involved in CIPN caused by
Long Gu, Song Cao, Yonghuai Feng
wiley +1 more source
Effective Medicinal Plant in Cancer Treatment, Part 2. [PDF]
, 2017 Cancer is the second cause of death after cardiovascular diseases. With due attention to rapid progress in the phytochemical study of plants, they are becoming popular because of their anticancer effects.
Asadi-Samani, Majid. +6 more
core
Chemotherapy and skin reactions. [PDF]
, 2012 BACKGROUND:New chemotherapic agents and new protocols in oncology have led to an increasing survival rate in patients affected by tumors. However, this increased use has been accompanied by a growth in the incidence of cutaneous side effects and a ...
Bianca D +6 more
core +1 more source
Vincristine induced cortical blindness: An alarming but reversible side effect
Pediatric Hematology Oncology Journal, 2016 Vincristine is one of the commonest chemotherapeutic agents in the practice of pediatric oncology. Although peripheral neuropathy is a dose limiting adverse event, blindness secondary to vincristine is seldom reported.
Sidharth Totadri, Amita Trehan
doaj +1 more source
Combinatory effect of BRCA1 and HERC2 expression on outcome in advanced non-small-cell lung cancer [PDF]
, 2016 BACKGROUND: BRCA1 is a main component of homologous recombination and induces resistance to platinum in preclinical models. It has been studied as a potential predictive marker in lung cancer. Several proteins modulate the function of BRCA1.
Bonanno, Laura +14 more
core +8 more sources
Taimsete produktide roll keemiaravi arengus [PDF]
, 2016 Vaatamata jõudsatele edasiminekutele vähiravis on pahaloomulised kasvajad endiselt üheks olulisemaks surmapõhjuseks kogu maailmas. WHO prognoositud haigestumise jätkuv kiire kasv lähiaastakümneil nõuab ka kemopreventiivsete ja kemoterapeutiliste meetmete
Kasemaa, Kristi, Sak, Katrin
core +2 more sources