Results 71 to 80 of about 83,539 (199)

Rational Use of Herbal Products in Pediatric Patients Treated With Anticancer Drugs in the European Union

Pediatric Blood &Cancer, Volume 73, Issue 9, September 2026.
ABSTRACT Introduction The use of herbal medical preparation (HMP) is rising among pediatric oncology patients, often to manage treatment‐related symptoms. Their effectiveness remains uncertain, and the risk of herb–drug interactions is underestimated.
Orianne Mahot, Mathieu Corvaisier, Laurence Spiesser‐Robelet, Mylène Duplan, Isabelle Pellier, Delphine Bourneau‐Martin, Séverine Derbré   +6 more
wiley   +1 more source

Isolation and X-ray crystal structure of tetrahydroisoquinoline alkaloids from Calycotome villosa Subsp. intermedias [PDF]

, 2004
Two tetrahydroisoquinoline alkaloids were extracted from the alkaloid fraction of a methanol extract of the seeds of Calycotome Villosa Subsp. intermedia.
Bolte, Michael, El Alami, Rachid, El Bali, Brahim, Messouri, Ibtissam, Bouktaib, Mohamed, Rachid El Alami, Brahim El Bali, Michael Bolte, El Antri, Ali, Mohamed Bouktaib, Ibtissam Messouri, Lachkar, Mohammed, Mohammed Lachkar, Ali El Antri   +13 more
core   +1 more source

STUDIES ON INDOLE-ALKALOIDS: PART I. PHYTOCHEMICAL INVESTIGATION OF CATHARANTHUS LANCEUS (APOCYNACEAE). PART II. CHEMOTAXONOMICAL STUDY OF VINCA LIBANOTICA (APOCYNACEAE).

, 1973
STUDIES ON INDOLE-ALKALOIDS: PART I. PHYTOCHEMICAL INVESTIGATION OF CATHARANTHUS LANCEUS (APOCYNACEAE). PART II. CHEMOTAXONOMICAL STUDY OF VINCA LIBANOTICA (APOCYNACEAE)
GEORGE HAGOP. AYNILIAN (7963448)
core   +6 more sources

DNA Binding Studies of Vinca Alkaloids: Experimental and Computational Evidence

Natural Product Communications, 2012
Fluorescence studies on the indole alkaloids vinblastine sulfate, vincristine sulfate, vincamine and catharanthine have demonstrated the DNA binding ability of these molecules.
Prateek Pandya, Surendra P. Gupta, Kumud Pandav, Ritu Barthwal, B. Jayaram, Surat Kumar   +5 more
doaj   +1 more source

Assessment of the Targeted Therapeutic Potential of Naringenin‐Benzyl Piperazine Derivatives on Hypoxia‐Induced JAK/STAT Pathway in Breast and Ovarian Cancers

Archiv der Pharmazie, Volume 359, Issue 9, September 2026.
The synthesized naringenin‐benzyl piperazine derivatives 3b, 3f, and 3g exhibited potent antiproliferative and cytotoxic activities on breast tumors (MCF7 (ER‐α+), SK‐Br, MDA‐MB‐231) and ovarian cancer cells (NIH‐OVCAR‐3, and SKOV‐3). 3f was found to have the highest apoptotic effect among the other derivatives.
Hafize Özcan, Oğuzhan Doğanlar, Zeynep Banu Doğanlar, Ayşen Şuekinci Yılmaz, Ömer Zaim   +4 more
wiley   +1 more source

Walsh & Hoyt: Vinca Alkaloids

, 2005
The vinca alkaloids, vincristine and vinblastine, are derived from the periwinkle plant. They bind to tubulin, prevent microtubular formation, and arrest cells in metaphase.
Mark L. Moster, MD; Rod Foroozan, MD
core  

Negative-Pressure Cavitation Extraction of Four Main Vinca Alkaloids from <em>Catharanthus </em><em>r</em><em>oseus</em> Leaves

Molecules, 2012
In the present study, an improved method termed negative-pressure cavitation extraction (NPCE) followed by reverse phase high-performance liquid chromatography (RP-HPLC) was developed for the extraction and quantification of vindoline (VDL ...
Yuangang Zu, Xiaorui Guo, Yujie Fu, Meng Luo, Wei Wang, Liuqing Yang, Fansong Mu   +6 more
doaj   +1 more source

Neurofilament light chain as in vitro and clinical biomarker of vincristine‐induced peripheral neuropathy

British Journal of Clinical Pharmacology, Volume 92, Issue 9, Page 3180-3190, September 2026.
Aims Vincristine‐induced peripheral neuropathy (VIPN) is a common side effect in children and adolescents treated with vincristine. Assessing VIPN, especially in young children, is challenging due to a lack of sensitive tools. This limits our understanding of the nature and risk factors of VIPN. This study aimed to investigate neurofilament light chain
Peter Erik Lotko Pontoppidan, Christian Bach Vase, Christina Mortensen, Liv Andres‐Jensen, Dorte Aalund Olsen, Jonna Skov Madsen, Kjeld Schmiegelow, Rene Mathiasen, Tore Bjerregaard Stage   +8 more
wiley   +1 more source

Investigação fitoquímica e biológica da espécie: Esenbeckia leiocarpa Engl. [PDF]

, 2012
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas. Programa de Pós-Graduação em Química.A investigação fitoquímica biomonitorada das cascas da espécie Esenbeckia leiocarpa confirmou a presença de ...
Horst, Heros
core  

The Biological Activity of the Novel Vinca Alkaloids 4-chlorochablastine and 4-chlorochacristine

, 2019
Background: Vinca alkaloids are important cancer drugs belonging to the class of antimitotic agents. The most commonly used substances are vinblastine and vincristine, other compounds are vinorelbine and vinflunine.
Henning Hintzsche, Helga Stopper, Gracia Montag, Quoc Anh Ngo   +3 more
core   +1 more source