Results 51 to 60 of about 16,117 (210)

Associations Between GLP‐1 Receptor Agonists and Alopecia: A Multi‐Centre Retrospective Analysis and Public Interest Trends

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Background There is a growing body of literature suggesting that GLP‐1 receptor agonists (GLP‐1RAs) may be associated with hair loss; however, primary literature is sparse. Additionally, it is not well‐established which types of hair loss may be associated with GLP‐1RA use. Objectives This study aims to assess associations between GLP‐1RAs and
Lauren M. Ching   +2 more
wiley   +1 more source

Cannabigerol reverses mechanical allodynia through α2A‐adrenergic modulation of thalamocortical signaling in chemotherapy‐induced neuropathy

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Chemotherapy‐induced peripheral neuropathy (CIPN) is a prevalent and treatment‐resistant side effect of platinum‐based chemotherapy, characterised by mechanical allodynia. Cannabigerol (CBG), a non‐psychoactive cannabinoid, has shown antinociceptive potential, but its site and mechanism of action remain unclear.
Quinn W. Wade   +7 more
wiley   +1 more source

THE ANTIMICROBIAL EFFECT OF GENUS VINCA ON SOME PATHOGEN MICROORGANISM

open access: yesIranian Journal of Public Health, 1995
Vinca major, minor and rosea are three species of vinca genus and Apocynaceae family. The present work is to investigate antimicrobial effects of these plants against Candida albicans, Pseudomonas aeroginosa and Staphylococus aureus.
S.Mehrab   +2 more
doaj  

Comparison of chemosensitivity tests: clonogenic assay versus MTT assay. [PDF]

open access: yes, 2002
When the development of chemotherapeutic agents reaches the clinical trial stage, it is necessary to perform drug sensitivity tests quickly in order to select the most promising agents for the treatment of cancer.
Harada, Mine   +7 more
core   +1 more source

Cancer pain: current practice and emerging targets

open access: yesBritish Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye   +5 more
wiley   +1 more source

Gas Chromatography-Mass Spectrometry (GC-MS) Analysis of Indole Alkaloids Isolated from Catharanthus roseus (L.) G. Don Cultivated Conventionally and Derived from In vitro Cultures

open access: yesNotulae Botanicae Horti Agrobotanici Cluj-Napoca, 2016
Catharanthus roseus (periwinkle) is a medicinal plant commonly known for its wide biological activity. In many countries different parts of this plant are used for the treatment of diabetes, hypertension and for menstrual regulation.
Aneta WESOŁOWSKA   +3 more
doaj   +1 more source

Protective effects of Vinca herbaceous extract against scopolamine-induced behavioral disturbances and brain oxidative stress in rats

open access: yesHeliyon, 2022
Ethnopharmacological relevance: Alzheimer's disease (AD) as the most common type of dementia, is affecting the life of many senior individuals around the world. Vinca herbacea Waldst. & Kit. (V.
Mir-Jamal Hosseini   +5 more
doaj   +1 more source

A phase II, multicentre, UK study of vinorelbine in advanced breast cancer. [PDF]

open access: yes, 2016
Clinical Trial, Phase IIMulticenter StudyFull text is available as a scanned copy of the original print versionThirty-four evaluable patients were treated with vinorelbine, a novel, semisynthetic vinca alkaloid, as first-line chemotherapy for advanced ...
Canney, P   +7 more
core  

Persistent in vitro nociceptor hyperexcitability and axonal retraction produced by repeated paclitaxel doses

open access: yesThe FEBS Journal, EarlyView.
Repeated paclitaxel exposure causes long‐lasting nociceptor hyperexcitability and axonal retraction in adult sensory neurons. Using a long‐term primary nociceptor culture, we show that hyperexcitability is mediated by sequential upregulation of NaV1.8, TRPV1, TRPA1, and TRPM8 channels.
Angela Lamberti   +3 more
wiley   +1 more source

A randomized, double-blind, placebo controlled, multi-center, phase III clinical trial to evaluate the efficacy of lamotrigine in the management of chemotherapy induced peripheral neuropathy [PDF]

open access: yes, 2015
Σημείωση: διατίθεται συμπληρωματικό υλικό σε ξεχωριστό ...
Τσιμπούρα, Παρασκευή
core   +1 more source

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