Cytostatic and Non-Apoptotic Effects of Vinorelbine-Based Therapy in 3D Endometrial Cancer Spheroids [PDF]
BiologyResistance to apoptosis represents a major therapeutic challenge in advanced and recurrent endometrial cancer. This study investigated whether vinorelbine, alone or in combination with lithium chloride (LiCl) or medroxyprogesterone acetate (MPA ...
Berna Yıldırım +3 more
doaj +2 more sources
Vinorelbine With or Without Thiotepa for HER2‐Negative Metastatic Breast Cancer: A Propensity Score Analysis [PDF]
Cancer MedicineBackground Vinorelbine is commonly used to treat metastatic breast cancer (mBC), while thiotepa is known for its ability to cross the blood–brain barrier.
Aurelia Robert +15 more
doaj +2 more sources
Symptomatic and pathological features in chemical phlebitis rat model by injection vinorelbine via dorsal pedal vein [PDF]
Scientific ReportsIntravenous administration of vesicants or irritants frequently leads to chemical phlebitis. We aimed to establish a chemical phlebitis rat model by injection vinorelbine via dorsal pedal vein and evaluate the general symptoms as well as the pathological
Haijie Ji +10 more
doaj +2 more sources
A Case Report of Advanced Pulmonary Adenocarcinoma in a Dog Managed with Chemotherapy and Cytokine-Based Immunotherapy [PDF]
AnimalsPulmonary adenocarcinoma in dogs, particularly in advanced stages, carries a poor prognosis with limited therapeutic options. Immunotherapeutic approaches that activate natural killer (NK) cells may provide additional clinical benefit.
Kyu-Duk Yeon, Ji-Hyuk Seo, Jung-Hyun Kim
doaj +2 more sources
Case Report of Acute Severe Hyponatremia Induced by Desmopressin Administration During Chemotherapy [PDF]
Clinical Case ReportsPatients undergoing chemotherapy are prone to developing hyponatremia due to insufficient oral intake because of nausea and vomiting, administration of large volumes of intravenous fluids, syndrome of inappropriate antidiuretic hormone secretion induced ...
Koutaro Ono +6 more
doaj +2 more sources
npj Breast Cancer, 2022 While therapies such as chemotherapy combined with immunotherapy, sacituzumab govitecan, and PARP inhibitors are available for metastatic TNBC, on disease progression after these therapies, the mainstay of therapy is chemotherapy.
Dou-Dou Li +6 more
doaj +1 more source
Phase I Study of Oral Vinorelbine in Combination with Erlotinib in Advanced Non-Small Cell Lung Cancer (NSCLC) Using Two Different Schedules. [PDF]
PLoS ONE, 2016 PURPOSE:This study aimed to evaluate the safety, tolerability and pharmacokinetics of the combination of oral vinorelbine with erlotinib using the conventional (CSV) and metronomic (MSV) dosing schedules in patients with advanced non-small cell lung ...
Natalia Sutiman +8 more
doaj +1 more source
Cells, 2023 Metastasis, rather than the growth of the primary tumor, accounts for approximately 90% of breast cancer patient deaths. Microtentacles (McTNs) formation represents an important mechanism of metastasis.
Vasileios Vardas +8 more
doaj +1 more source
Frontiers in Oncology, 2021 IntroductionPyrotinib plus capecitabine has been approved in China for human epidermal growth factor receptor 2 (HER2)-positive metastatic breast cancer (MBC).
Yi Li +9 more
doaj +1 more source
Oral Chemotherapy for Treatment of Lung Cancer
Frontiers in Oncology, 2020 The global COVID-19 pandemic has disrupted healthcare delivery, particularly for patients with advanced lung cancer. While certain aspects of care can be safely omitted or delayed, systemic therapy plays an important role in survival and quality of life ...
Sushma Jonna +3 more
doaj +1 more source