Results 11 to 20 of about 15,297 (160)

Oral Chemotherapy for Treatment of Lung Cancer

Frontiers in Oncology, 2020
The global COVID-19 pandemic has disrupted healthcare delivery, particularly for patients with advanced lung cancer. While certain aspects of care can be safely omitted or delayed, systemic therapy plays an important role in survival and quality of life ...
Sushma Jonna, Joshua E. Reuss, Chul Kim, Stephen V. Liu   +3 more
doaj   +1 more source

Efficacy and safety of inetetamab-containing regimens in patients with HER2-positive metastatic breast cancer: a real-world retrospective study in China

Frontiers in Oncology, 2023
BackgroundInetetamab (cipterbin) is an innovative anti-HER2 humanized monoclonal antibody. The efficacy and safety of a combination of inetetamab and vinorelbine in the first-line treatment of human epidermal receptor positive (HER2+) metastatic breast ...
Xiaoyu Liu, Peng Zhang, Chao Li, Xiang Song, Xiang Song, Zhaoyun Liu, Wenna Shao, Sumei Li, Xinzhao Wang, Xinzhao Wang, Zhiyong Yu, Zhiyong Yu   +11 more
doaj   +1 more source

Effects of Pachyman in Combination with Vinorelbine and Cisplatin on Tumor Growth and the Expression of EGFR and K-ras in Mice with Lung Cancer

Digital Chinese Medicine, 2018
: Objective To examine the effects of pachyman in combination with vinorelbine and cisplatin on tumor growth and the expression of epidermal growth factor receptor (EGFR) and K-ras in a mouse model of lung cancer induced using the human lung cancer cell ...
Ke WEI, Jia-Hao ZHOU, Yong-Chao CHEN, Jia-Ming TIAN, Meng-Jin SUN, Xin-Wen DAI, Bai-Hui LI, Ling LI, Fang-Liang ZHOU, Yi NING, Jue HU, Qin XIANG, Bo ZHANG, Fang-Guo LU   +13 more
doaj   +1 more source

Active symptom control with or without oral vinorelbine in patients with relapsed malignant pleural mesothelioma (VIM): A randomised, phase 2 trial

EClinicalMedicine, 2022
Summary: Background: Currently, there is no US Food and Drug Administration approved therapy for patients with pleural mesothelioma who have relapsed following platinum-doublet based chemotherapy. Vinorelbine has demonstrated useful clinical activity in
Dean A. Fennell, Catharine Porter, Jason Lester, Sarah Danson, Paul Taylor, Michael Sheaff, Robin M Rudd, Aarti Gaba, Sara Busacca, Lisette Nixon, Georgina Gardner, Liz Darlison, Charlotte Poile, Cathy Richards, Peter-Wells Jordan, Gareth Griffiths, Angela Casbard   +16 more
doaj   +1 more source

Risk factors for venous irritation in patients receiving vinorelbine: a retrospective study

Journal of Pharmaceutical Health Care and Sciences, 2018
Background Vinorelbine is known to be effective in the treatment of non-small cell lung cancer and breast cancer. However, venous irritation is a common side effect.
Yoshihito Morimoto, Kumika Miyawaki, Reisuke Seki, Kazuhiro Watanabe, Masayoshi Hirohara, Takao Shinohara   +5 more
doaj   +1 more source

Alveolar rhabdomyosarcoma has superior response rates to vinorelbine compared to embryonal rhabdomyosarcoma in patients with relapsed/refractory disease: A meta‐analysis

Cancer Medicine, 2023
Background Patients with alveolar rhabdomyosarcoma (ARMS) have inferior outcomes compared to patients with embryonal rhabdomyosarcoma (ERMS) and more effective chemotherapy options are needed for these patients.
Wendy Allen‐Rhoades, Philip J. Lupo, Michael E. Scheurer, Yueh‐Yun Chi, John F. Kuttesch, Rajkumar Venkatramani, William H. Meyer, Leo Mascarenhas   +7 more
doaj   +1 more source

Comparison between Vinorelbine–Carboplatin and Vinorelbine–Cisplatin in Stage III–IV EGFR Mutations-Negative NSCLC

Asian Journal of Oncology, 2022
Introduction There are a substantial number of lung cancer patients with negative mutations in Indonesia. This type of cancer is deemed to be the major contributor of lung cancer patient’s death.
Laksmi Wulandari, Gatot Soegiarto, Anna Febriani, Farah Fatmawati, Wirya Sastra Amran   +4 more
doaj   +1 more source

Unforeseen cytomegalovirus retinopathy following high dose thiotepa and proton irradiation in a pediatric patient with high-risk medulloblastoma: A case report

Frontiers in Pediatrics, 2023
In immunocompetent individuals, cytomegalovirus (CMV) infection is usually mild but may cause severe complications such as retinitis, pneumonitis, and encephalitis in immunocompromised individuals.
Elisabetta Bigagli, Sara Agostiniani, Alessandra Pugi, Barbara Rombi, Elena Eve Tornaboni, Maria Luigia Censullo, Carlotta Gemma Gori, Rossana Pavone, Iacopo Sardi   +8 more
doaj   +1 more source

Pharmacoeconomic aspects of oral vinorelbine application: a budget impact analysis considering the new registered price

Фармакоэкономика, 2021
Objective: comparative assessment of the economic effect of oral vinorelbine when used as indicated, taking into consideration the new registered price.Material and methods.
D. A. Ivanov, I. N. Dyakov, S. K. Zyryanov   +2 more
doaj   +1 more source

Microtubule disruption reduces metastasis more effectively than primary tumor growth

Breast Cancer Research, 2022
Clinical cancer imaging focuses on tumor growth rather than metastatic phenotypes. The microtubule-depolymerizing drug, Vinorelbine, reduced the metastatic phenotypes of microtentacles, reattachment and tumor cell clustering more than tumor cell ...
Keyata N. Thompson, Julia A. Ju, Eleanor C. Ory, Stephen J. P. Pratt, Rachel M. Lee, Trevor J. Mathias, Katarina T. Chang, Cornell J. Lee, Olga G. Goloubeva, Patrick C. Bailey, Kristi R. Chakrabarti, Christopher M. Jewell, Michele I. Vitolo, Stuart S. Martin   +13 more
doaj   +1 more source