Addition of Vindoline to p-Benzoquinone: Regiochemistry, Stereochemistry and Symmetry Considerations
Molecules, 2021 Vindoline and catharanthine are the major alkaloids of Catharanthus roseus and are extracted in large quantities to prepare the pharmaceutically important Vinca type alkaloids vincaleukoblastine, vincristine and navelbine.
Shamsher Ali +3 more
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Integrated metabolomic, network pharmacological, and molecular docking analyses comparing the therapeutic effects of Strobilanthes sarcorrhiza from different origins [PDF]
Scientific ReportsStrobilanthes sarcorrhiza, a characteristic medicinal plant in China, has been traditionally used for nourishing yin and tonifying kidneys through its fleshy roots.
Wenyuan Xie +7 more
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Endophytic bacteria of Catharanthus roseus as an alternative source of Vindoline and application of response surface methodology to enhance its production [PDF]
Archives of Biological Sciences, 2019 The requirement for novel, cost-effective pharmaceutical compounds is growing. We screened endophytic bacteria of Catharanthus roseus for the production of vinca alkaloids.
Anjum Nawed, Chandra Ramesh
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FASEB Journal, 2022 Intestinal inflammation and intestinal barrier damage are important pathological changes in Crohn's disease (CD). Vindoline is a natural monomer with anti‐inflammatory effects.
Zhang Xiaofeng, Jianguo Hu
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Kufa Journal for Agricultural SciencesPeriwinkle Cathranthus roseus is an ornamental plant that produces over 200 alkaloids, including vincristine, vinblastine, and vindoline, which are used to treat various types of cancer.
Zainab Abdulwahid +2 more
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Magnesium Plus Hydrogen Fertilization Enhances Mg Uptake, Growth Performance and Monoterpenoid Indole Alkaloid Biosynthesis in Catharanthus roseus [PDF]
PlantsMagnesium and hydrogen fertilization have been reported to contribute to plant growth and metabolite production. Simultaneous fertilization of magnesium and hydrogen is a promising strategy for plant development and secondary metabolism, but remains ...
Chaoqin Ou +9 more
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Biomedicines, 2019 Cardiovascular diseases (CVDs) and kidney diseases in diabetes are linked to increased mortality and morbidity. The aim of this study was to evaluate the effect of vindoline derived from Catharanthus roseus in diabetes-induced CVDs and kidney disease ...
Oluwafemi Omoniyi Oguntibeju +2 more
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Transcriptomic profiling and oxidative stress responses of Catharanthus roseus under short-term LED light exposure [PDF]
BMC Plant BiologyAs the application of LED light on plants is increasing for development of efficient, sustainable, and innovative agricultural strategies, comprehensive knowledge towards response mechanisms of plants under such artificial light source is less known.
Zhuoheng Zhong +5 more
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Enhancement of vindoline and catharanthine production in Catharanthus roseus by LED light and plasma activated water. [PDF]
PLoS OneThis study aimed to increase the concentrations of vindoline (VDL) and catharanthine (CAT) in Catharanthus roseus plants cultivated in an indoor farming system using artificial lighting and plasma-activated water (PAW).
Quadri A +9 more
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Biomedicine and Pharmacotherapy, 2019 Vindoline, an indole alkaloid present in the leaves of Catharanthus roseus plant, has been recently reported to have insulotropic effects. This present study evaluated the possible hepatoprotective effects of vindoline in a type 2 diabetes mellitus rat ...
Yapo Guillaume Aboua +2 more
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