Functional diversity of 2-oxoglutarate/Fe(II)-dependent dioxygenases in plant metabolism [PDF]
, 2014 Oxidative enzymes catalyze many different reactions in plant metabolism. Among this suite of enzymes are the 2-oxoglutarate/Fe(II)-dependent dioxygenases (2-ODDs). Cytochromes P450 (CYPs) as often considered the most versatile oxidative enzymes in nature,
Peter J. Facchini, Scott C. Farrow
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Catharanthus roseus (L.) G. Don - plant regeneration and alkaloids content
Acta Societatis Botanicorum Poloniae, 2014 We describe here a regeneration of plantlets of Catharanthus roseus (L.) G. Don from shoot tips and axillary buds. Shoot tips were excised from 7-day-old seedlings and were incubated in solid Nitsch and Nitsch (NN) medium supplemented with kinetin ...
Mirosława Furmanowa +3 more
doaj +1 more source
Conversion of Vindoline into 11-Mesyloxytabersonine
CHEMICAL & PHARMACEUTICAL BULLETIN, 2016 Conversion of readily available vindoline to 11-mesyloxytabersonine, a versatile synthetic intermediate for indole alkaloids, has been achieved by a 9-step sequence in 39% overall yield.
Yuki, Han-Ya +4 more
openaire +3 more sources
A microbial supply chain for production of the anti-cancer drug vinblastine [PDF]
, 2022 International audienceAbstract Monoterpene indole alkaloids (MIAs) are a diverse family of complex plant secondary metabolites with many medicinal properties, including the essential anti-cancer therapeutics vinblastine and vincristine 1 .
Adhikari, K. +29 more
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Engineering and Applications of fungal laccases for organic synthesis [PDF]
, 2008 Laccases are multi-copper containing oxidases (EC 1.10.3.2), widely distributed in fungi, higher plants and bacteria. Laccase catalyses the oxidation of phenols, polyphenols and anilines by one-electron abstraction, with the concomitant reduction of ...
Ballesteros Antonio +5 more
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Plant-Based Indole Alkaloids: A Comprehensive Overview from a Pharmacological Perspective
Molecules, 2021 Plant-based indole alkaloids are very rich in pharmacological activities, and the indole nucleus is considered to contribute greatly to these activities.
Faisal Omar +6 more
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Vinorelbine with or without Trastuzumab in Metastatic Breast Cancer: A Retrospective Single Institution Series [PDF]
, 2014 Background. We report our experience with vinorelbine, a widely used chemotherapeutic, in unselected metastatic breast cancer patients treated in clinical routine. Patients and Methods.
Stravodimou, A. +2 more
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Natural Product Communications, 2015 Vincristine and vinblastine were found by Liquid Chromatography-Mass Spectrometry (LC-MS) in Catharanthus roseus cambial meristem cells (CMCs) jointly treated with 0.25 mM vindolineand methyl jasmonate (MeJA), suggesting that C.
Wenjin Zhang +5 more
doaj +1 more source
Comparative study of the hypoglycemic and biochemical effects of Catharanthus roseus (Linn) g. apocynaceae (Madagascar periwinkle) and chlorpropamide (diabenese) on alloxan-induced diabetic rats [PDF]
, 2005 The effect of the aqueous extracts of Catharanthus roseus and chlorpropamide (Diabenese) on the levels of serum cholesterol, total protein, lipid peroxidation, blood glucose and liver enzymes were compared in alloxan-induced diabetic rats.
Iweala, E. E. J., Okeke, C. U.
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Characterisation of two alcohol acyltransferases from kiwifruit (Actinidia spp.) reveals distinct substrate preferences. [PDF]
, 2011 Volatile esters are key compounds of kiwifruit flavour and are formed by alcohol acyltransferases that belong to the BAHD acyltransferase superfamily.
Chervin, Christian +4 more
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