Electrospray–Mass Spectrometry-Guided Targeted Isolation of Indole Alkaloids from Leaves of Catharanthus roseus by Using High-Performance Countercurrent Chromatography [PDF]
MoleculesElectrospray mass spectrometry off-line profiling monitored the recovery of targeted indole alkaloids from a fortified crude extract of Catharanthus roseus (790 mg) using semi-preparative high-performance countercurrent chromatography (HPCCC ...
Mahdi Yahyazadeh +2 more
doaj +2 more sources
Dietary Supplement with Milk that Contains Different β-Caseins Influences Gut Microbiota and Serum Metabolites in Mice [PDF]
Food Science of Animal ResourcesThe composition and metabolites of gut microbiota are shaped by dietary protein, consequently affecting host physiology, health, and diseases. This study aimed to elucidate the role of β-caseins in remodeling the composition of colon microbiota and the ...
Xiangzhen Gao +13 more
doaj +2 more sources
A Cotyledon-based Virus-Induced Gene Silencing (Cotyledon-VIGS) approach to study specialized metabolism in medicinal plants [PDF]
Plant MethodsBackground Virus-induced gene silencing (VIGS) is widely used in plant functional genomics. However, the efficiency of VIGS in young plantlets varies across plant species.
Yongliang Liu +5 more
doaj +2 more sources
Comprehensive analysis of SPL gene family and miR156a/SPLs in the regulation of terpenoid indole alkaloid biosynthesis in Catharanthus roseus L [PDF]
BMC Plant BiologyBackground Catharanthus roseus (C. roseus), belongs to the dogbane family Apocynaceae, is the source of various terpenoid indole alkaloids (TIAs) with excellent antitumor properties, including vinblastine, vincristine, ajmalicine, serpentine, vindoline ...
Yaojie Zhang +9 more
doaj +2 more sources
Asymmetric Total Synthesis of Vindoline [PDF]
Journal of the American Chemical Society, 2010 A concise asymmetric total synthesis of (-)-vindoline (1) is detailed based on a tandem intramolecular [4+2]/[3+2] cycloaddition cascade of a 1,3,4-oxadiazole inspired by the natural product structure, in which the tether linking the initiating dienophile and oxadiazole bears a chiral substituent that controls the facial selectivity of the initiating ...
Daisuke, Kato +2 more
openaire +5 more sources
Frontiers in Genetics, 2022 Catharanthus roseus produces terpenoid indole alkaloids (TIAs) of high medicinal importance. The current research focuses on finding an efficient production system such as cell suspension cultures for high TIA concentrations.
Pengfei Zhou, Mingxiang Chen
doaj +1 more source
Total Synthesis of (−)- and ent-(+)-Vindoline [PDF]
Organic Letters, 2005 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Younggi, Choi +5 more
openaire +6 more sources
Attempted Synthesis of Vinca Alkaloids Condensed with Three-Membered Rings
Molecules, 2018 Our successful work for the synthesis of cyclopropanated vinblastine and its derivatives by the Simmons–Smith reaction was followed to build up further three-membered rings into the 14,15-position of the vindoline part of the dimer alkaloid ...
András Keglevich +8 more
doaj +1 more source
Frontiers in Plant Science, 2023 NAC transcription factors (TFs) are crucial to growth and defense responses in plants. Though NACs have been characterized for their role in several plants, comprehensive information regarding their role in Catharanthus roseus, a perennial ornamental ...
Jawad Ahmed +9 more
doaj +1 more source
Isolation, purification and characterization of vindoline from Catharanthus roseus
International Journal of Science and Research Archive, 2023 Catharanthus roseus is a popular medicinal plant available all over the world. Across the globe, different parts of the plant are used to treat diabetes, hypertension, cancer, and menstrual abnormalities.
Raghu Nataraj +3 more
semanticscholar +1 more source