Results 101 to 110 of about 27,363 (202)

Synergistic Antitumor Efficacy Mediated by Liposomal Co-Delivery of Polymeric Micelles of Vinorelbine and Cisplatin in Non-Small Cell Lung Cancer

International Journal of Nanomedicine, 2021
Shuhang Wang,1 Jingxin Gou,2 Yue Wang,1 Xinyi Tan,2 Linxuan Zhao,1 Xiangqun Jin,1 Xing Tang2 1Department of Pharmaceutics, College of Pharmacy Sciences, Jilin University, Changchun, 130021, Jilin, People’s Republic of China; 2Department of ...
Wang S, Gou J, Wang Y, Tan X, Zhao L, Jin X, Tang X   +6 more
doaj  

A phase II, multicentre, UK study of vinorelbine in advanced breast cancer. [PDF]

, 2016
Clinical Trial, Phase IIMulticenter StudyFull text is available as a scanned copy of the original print versionThirty-four evaluable patients were treated with vinorelbine, a novel, semisynthetic vinca alkaloid, as first-line chemotherapy for advanced ...
Canney, P, Coleman, RE, Curnow, Alison, Dobbs, NA, Rubens, RD, Stewart, AL, Twelves, CJ, Tyrrell, CJ   +7 more
core  

Dynamic Evaluation of Vinorelbine-Induced Phlebitis of Dorsalis Pedis Vein in a Rat Model

Shiyan dongwu yu bijiao yixue
ObjectiveTo dynamically observe the clinical symptoms and pathological changes in a rat model of vinorelbine-induced phlebitis via injection into the dorsalis pedis vein.MethodsTwenty-eight 11-week-old male SPF-grade SD rats were randomly divided into a ...
JIANG Meng, HAO Shulan, TONG Liguo, ZHONG Qiming, GAO Zhenfei, WANG Yonghui, WANG Xixing, JI Haijie   +7 more
doaj   +1 more source

Overcoming Breast Cancer Drug Resistance: A Novel Approach Using siRNA-Mediated P-glycoprotein Downregulation to Enhance Vinorelbine Efficacy [PDF]

Advanced Pharmaceutical Bulletin
Purpose: Cancer, the second leading cause of mortality worldwide, represents a global health challenge, primarily due to drug resistance. Vinorelbine is a chemotherapeutic agent that disrupts cancer cell growth by targeting microtubules and inducing ...
Zahra Abbasfard, Abbas Behzad-Behbahani, Banafshe Rastegari, Sirous Naeimi, Mehdi Moghanibashi, Fatemeh Safari   +5 more
doaj   +1 more source

Final results of a phase I/II pilot study of capecitabine with or without vinorelbine after sequential dose-dense epirubicin and paclitaxel in high-risk early breast cancer

BMC Cancer, 2010
Background The integration of the non-cross-resistant chemotherapeutic agents capecitabine and vinorelbine into an intensified dose-dense sequential anthracycline- and taxane-containing regimen in high-risk early breast cancer (EBC) could improve ...
Müller Volkmar, Thomssen Christoph, Schmidt Marcus, Glados Manfred, Jackisch Christian, Heilmann Volker, Hinke Axel, Lehnert Antje, Borowicz Henryk, Möbus Volker   +9 more
doaj   +1 more source

Eficacia de la combinación de Vinorelbine- Trastuzumab en carcinoma de mama metastásico con sobreexpresión de HER2, previamente tratado con Trastuzumab [PDF]

, 2013
L'addició de Trastuzumab a quimioteràpia basada en taxans millora la supervivència de les pacients amb carcinoma de mama metastàtic i sobreexpressió de HER2.
Cortés, Javier, Rodríguez Freixinós, Víctor, Suriñach Caralt, Josep Mª, Universitat Autònoma de Barcelona. Departament de Medicina, Universitat Autònoma de Barcelona. Facultat de Medicina   +4 more
core  

Correlation between radioactivity and chemotherapeutics of the 111In-VNB-liposome in pharmacokinetics and biodistribution in rats

International Journal of Nanomedicine, 2012
Wen-Chuan Lee1,*, Chih-Hsien Chang2,3,*, Chih-Min Huang1, Yu-Tse Wu1, Liang-Cheng Chen2, Chung-Li Ho2, Tsui-Jung Chang2, Te-Wei Lee2, Tung-Hu Tsai1,41Institute of Traditional Medicine, School of Medicine, National Yang-Ming University, Taipei, 2Division ...
Tsai TH, Lee TW, Chang TJ, Ho CL, Chen LC, Wu YT, Huang CM, Chang CH, Lee WC   +8 more
doaj  

Response Rate,Side Effect and Reduction in Tumor Size of Vinorelbine, Gemcitabine and Taxanes as First Line Setting of Advanced Squamous Cell Carcinoma of the Lung

Diyala Journal of Medicine
Background: Squamous-cell carcinoma (SCC) of the lung is a kind of non-small-cell lung carcinoma. Cytotoxic chemotherapy has been found to deliver benefits to patients in advanced disease settings. Objective: To compare response rate and side effects
Shahbaa Ahmed AL Qadasi,, Azhar Sabieh Al Zubaidi   +1 more
doaj   +1 more source

Meta-analysis of stomatitis in clinical studies of everolimus: incidence and relationship with efficacy. [PDF]

, 2016
BackgroundEverolimus, an oral mammalian target of rapamycin (mTOR) inhibitor, is used to treat solid tumors and tuberous sclerosis complex (TSC). Stomatitis, an inflammation of the mucous membranes of the mouth, is a common adverse event associated with ...
Anak, O, Franz, D, Gallo, J, Hortobagyi, GN, Motzer, R, Pavel, M, Ravaud, A, Ringeisen, F, Rouyrre, N, Rugo, HS, Yao, J   +10 more
core  

Predicting drug response of tumors from integrated genomic profiles by deep neural networks

, 2018
The study of high-throughput genomic profiles from a pharmacogenomics viewpoint has provided unprecedented insights into the oncogenic features modulating drug response.
Chen, Hung-I Harry, Chen, Yidong, Chiu, Yu-Chiao, Gorthi, Aparna, Huang, Yufei, Wang, Li-Ju, Zhang, Songyao, Zhang, Tinghe   +7 more
core   +1 more source