Results 41 to 50 of about 1,568,281 (351)

Spatial expansions and travelling waves of rabies in vampire bats [PDF]

, 2016
A major obstacle to anticipating the cross-species transmission of zoonotic diseases and developing novel strategies for their control is the scarcity of data informing how these pathogens circulate within natural reservoir populations.
Benavides, Julio A., Streicker, Daniel, Valderrama, William   +2 more
core   +1 more source

Microneedle patch as a new platform to effectively deliver inactivated polio vaccine and inactivated rotavirus vaccine

npj Vaccines, 2022
We recently reported a lack of interference between inactivated rotavirus vaccine (IRV) and inactivated poliovirus vaccine (IPV) and their potential dose sparing when the two vaccines were administered intramuscularly either in combination or standalone ...
Sung-Sil Moon, Marly Richter-Roche, Theresa K. Resch, Yuhuan Wang, Kimberly R. Foytich, Houping Wang, Bernardo A. Mainou, Winston Pewin, Jeongwoo Lee, Sebastien Henry, Devin V. McAllister, Baoming Jiang   +11 more
doaj   +1 more source

Virus and host factors affecting the clinical outcome of bluetongue virus infection [PDF]

, 2014
Bluetongue is a major infectious disease of ruminants caused by bluetongue virus (BTV), an arbovirus transmitted by Culicoides. Here, we assessed virus and host factors influencing the clinical outcome of BTV infection using a single experimental ...
Caporale, Marco, Di Gialleonorado, Luigina, Di Ventura, Mauro, Janowicz, Anna, Mertens, Peter, Palmarini, Massimo, Savini, Giovanni, Shaw, Andrew, Van Rijn, Piet A., Wilkie, Gavin   +9 more
core   +3 more sources

Isolation of a Novel Bat Rhabdovirus with Evidence of Human Exposure in China

mBio, 2022
Bats are well-recognized reservoirs of zoonotic viruses. Several spillover events from bats to humans have been reported, causing severe epidemic or endemic diseases including severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2), SARS-CoV, Middle
Li-Li Li, Ya-Long Xu, Xue-Xin Lu, Hong-Yan Deng, Jin-Song Li, Jing-Dong Song, Xiao-Hua Ma, Wu-Yang Zhu, Jing-Lin Wang, Zhao-Jun Duan   +9 more
doaj   +1 more source

Gut immune dysfunction through impaired innate pattern recognition receptor expression and gut microbiota dysbiosis in chronic SIV infection. [PDF]

, 2016
HIV targets the gut mucosa early in infection, causing immune and epithelial barrier dysfunction and disease progression. However, gut mucosal sensing and innate immune signaling through mucosal pattern recognition receptors (PRRs) during HIV infection ...
Bäumler, AJ, Dandekar, S, Gaulke, CA, Glavan, TW, Goulart, LR, Hirao, LA, Jiang, G, Raffatellu, M, Sankaran-Walters, S, Santos Rocha, C   +9 more
core   +2 more sources

Projections of the healthcare costs and disease burden due to hepatitis C infection under different treatment policies in Malaysia, 2018-2040 [PDF]

, 2018
The World Health Organisation (WHO) has set ambitious goals to reduce the global disease burden associated with, and eventually eliminate, viral ...
A Hill, A Thomas, Adeeba Kamarulzaman, Amirah Azzeri, B Devleesschauwer, CJL Murray, D Lunn, EB Tapper, Fatiha Hana Shabaruddin, GJ Dore, J Iversen, JJ Heidelbaugh, Maznah Dahlui, MC Cheung, ME Stouthard, Ministry of Health Malaysia, P Vemer, Rosmawati Mohamed, SA McDonald, SA McDonald, Scott A. McDonald, Seng Gee Lim, Soek S. Tan, SS Tan, The Kirby Institute, TM Welzel, VJ Wirtz, World Health Organisation, World Health Organisation, World Health Organisation   +29 more
core   +1 more source

Epidemiological characteristics of imported respiratory infectious diseases in China, 2014‒2018

Infectious Diseases of Poverty, 2022
Background With the progress of globalization, international mobility increases, greatly facilitating cross-border transmission of respiratory infectious diseases (RIDs).
Jin-Long Wang, Tao Chen, Le-Le Deng, Ya-Jun Han, Da-Yan Wang, Li-Ping Wang, Guang-Xue He   +6 more
doaj   +1 more source

Infants hospitalized for Bordetella pertussis infection commonly have respiratory viral coinfections [PDF]

, 2017
Background: Whether viral coinfections cause more severe disease than Bordetella pertussis (B. pertussis) alone remains unclear. We compared clinical disease severity and sought clinical and demographic differences between infants with B.
Agricola, Eleonora, Buttinelli, Gabriele, Campagna, Ilaria, Carsetti, R., Concato, C., DI MATTIA, Greta, Fedele, Giorgio, Ferretti, Beatrice, Frassanito, Antonella, Gesualdo, Francesco, Gonfiantini, Michaela Veronika, Marcellini, Valentina, Midulla, Fabio, Nenna, Raffaella, Nicolai, Ambra, Pandolfi, Elisabetta, Pierangeli, Alessandra, Russo, Luisa, Schiavoni, I., Stefanelli, P., Tozzi, A. E., Vennarucci, Valentina Spuri, Villani, Alberto   +22 more
core   +1 more source

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

FEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali, Gloria Giacomello, Michela Vuono, Silvia Gregori   +3 more
wiley   +1 more source

Abnormal upregulation of cardiovascular disease biomarker PLA2G7 induced by proinflammatory macrophages in COVID-19 patients

Scientific Reports, 2021
High rate of cardiovascular disease (CVD) has been reported among patients with coronavirus disease 2019 (COVID-19). Importantly, CVD, as one of the comorbidities, could also increase the risks of the severity of COVID-19.
Yang Li, Yongzhong Jiang, Yi Zhang, Naizhe Li, Qiangling Yin, Linlin Liu, Xin Lv, Yan Liu, Aqian Li, Bin Fang, Jiajia Li, Hengping Ye, Gang Yang, Xiaoxian Cui, Yang Liu, Yuanyuan Qu, Chuan Li, Jiandong Li, Dexin Li, Zhongtao Gai, Shiwen Wang, Faxian Zhan, Mifang Liang   +22 more
doaj   +1 more source