Results 101 to 110 of about 447,313 (350)

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Viral Evolution and Adaptation as a Multivariate Branching Process

, 2013
In the present work we analyze the problem of adaptation and evolution of RNA virus populations, by defining the basic stochastic model as a multivariate branching process in close relation with the branching process advanced by Demetrius, Schuster and ...
Antoneli, Fernando, Bosco, Francisco, Castro, Diogo, Janini, Luiz Mário Ramos, Mondaini, R. P.   +4 more
core   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Characterization of SARS-CoV-2 viral diversity within and across hosts [PDF]

, 2020
Palash Sashittal, Yunan Luo, Jian Peng, Mohammed El-Kebir   +3 more
openalex   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Characterization of multiple human papillomavirus types in the human vagina following ovarian hormonal stimulation

Virology Journal
The objective of study was to characterize HPV in vaginal samples from women being seen at the Center for Reproductive Medicine and Infertility at Weill Cornell Medicine before and following ovarian stimulation. A total of 29 women made samples available
Endrya do Socorro Foro Ramos, Roseane da Silva Couto, Tania Regina Tozetto-Mendoza, Pietro Bortoletto, Erick Matheus Garcia Barbosa, Noely Evangelista Ferreira, Iara M. Linhares, Steven D. Spandorfer, Antonio Charlys da Costa, Elcio Leal, Maria Cassia Mendes-Correa, Steven S. Witkin   +11 more
doaj   +1 more source

How eBSV polymorphism could enlighten BSV and banana evolution story? [PDF]

, 2013
The nuclear genome of banana plants is invaded by numerous viral sequences of banana streak viruses (BSV), a DNA virus belonging to the family Caulimoviridae.
Duroy, Pierre-Olivier, Iskra Caruana, Marie-Line, Jacquemoud-Collet, Jean-Pierre, Laboureau, Nathalie, Perrier, Xavier   +4 more
core  

Virus isolation studies suggest short-term variations in abundance in natural cyanophage populations of the Indian Ocean [PDF]

, 2006
Cyanophage abundance has been shown to fluctuate over long timescales and with depth, but little is known about how it varies over short timescales. Previous short-term studies have relied on counting total virus numbers and therefore the phages which ...
Clokie, Martha R. J., Mann, Nicholas H., Mehta, Jaytry Y., Millard, Andrew D.   +3 more
core   +2 more sources

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Metavirome Insights into the Diversity and Potential Pathogenic Infection of Chlamys farreri in the Coastal Seas of the Republic of Korea

Pathogens
Chlamys farreri is primarily cultivated in Japan, China, and South Korea. Although mass mortality of scallops has been occurring recently, likely caused by high temperatures or infectious diseases, the underlying cause remains unclear.
Ji Woo Shin, Kang Eun Kim, Joon Sang Park, Min-Jeong Kim, Taek-Kyun Lee, Yu Jin Kim, Hyun-Jung Kim, Seon Min Kim, Seung Won Jung   +8 more
doaj   +1 more source